当前位置： SCI文献检索 > JOURNAL OF PEDIATRIC SURGERY期刊下所有文献 > Pancreatectomies for pediatric pancreatic tumors: A single institute experience from 2007 to 2018.

Pancreatectomies for pediatric pancreatic tumors: A single institute experience from 2007 to 2018.

Abstract：

BACKGROUND:To investigate the safety, feasibility, and complications of pancreatectomies for pediatric pancreatic tumors. METHODS:The medical records of pancreatectomy patients from January 2007 to January 2018 were retrospectively analyzed for perioperative factors and complications. Patients were divided into pancreatic head (n = 43), body (n = 18) and tail (n = 43) groups. RESULTS:Seventy-two girls and 32 boys (median age 10 years at diagnosis, range: 0-15 years) were enrolled and had solid pseudopapillary tumors (n = 73), pancreatoblastoma (n = 19), neuroendocrine tumors (n = 9), and others. Primary surgical procedures included pylorus-preserving pancreaticoduodenectomy (n = 10) and distal pancreatectomy with splenectomy (n = 4), and organ-sparing resection procedures included duodenum-preserving pancreas head resection (n = 25), middle segmental pancreatic resection (n = 15), spleen-preserving distal pancreatectomy (n = 37) and local enucleation (n = 13), with a median blood loss of 20 cm3 (range: 10-300 cm3). Short-term complications included pancreatic fistula (35.6%), bile leakage (2.9%), intraabdominal infection (21.2%), delayed gastric emptying (23.1%), and postpancreatectomy hemorrhage (5.8%). After a median follow-up of 38 months (range: 3-143 months), 94 patients (90.4%) were alive without tumor recurrence, 2 were alive after tumor recurrence, 1 pancreatoblastoma patient died from tumor recurrence, and 7 were lost to follow-up. Only 14 patients (14/96, 14.6%) had long-term complications at the outpatient follow-up. CONCLUSIONS:Surgical resection was the main treatment for pancreatic tumors. Organ-sparing resection procedures led to good long-term results for pediatric pancreatic tumors, even if these procedures could cause a relatively high incidence of short-term complications (especially pancreatic fistula and postpancreatectomy hemorrhage). LEVEL OF EVIDENCE:Level IV.

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Cheng H,Yang S,Ren Q,Yang W,Han W,Chang X,Zhu Z,Qin H,Wang H

doi

10.1016/j.jpedsurg.2019.08.051

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

1722-1726

issue

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(19)30591-3

journal_volume

pub_type

杂志文章

在线工具

Pancreatectomies for pediatric pancreatic tumors: A single institute experience from 2007 to 2018.