Abstract:
:By removing a part of the structure, the tooth preparation provides restorative space, bonding surface, and finish line for various restorations on abutment. Preparation technique plays critical role in achieving the optimal result of tooth preparation. With successful application of microscope in endodontics for >30 years, there is a full expectation of microscopic dentistry. However, as relatively little progress has been made in the application of microscopic dentistry in prosthodontics, the following assumptions have been proposed: Is it suitable to choose the tooth preparation technique under the naked eye in the microscopic vision? Is there a more accurate preparation technology intended for the microscope? To obtain long-term stable therapeutic effects, is it much easier to achieve maximum tooth preservation and retinal protection and maintain periodontal tissue and oral function health under microscopic vision? Whether the microscopic prosthodontics is a gimmick or a breakthrough in obtaining an ideal tooth preparation should be resolved in microscopic tooth preparation. This article attempts to illustrate the concept, core elements, and indications of microscopic minimally invasive tooth preparation, physiological basis of dental pulp, periodontium and functions involved in tool preparation, position ergonomics and visual basis for dentists, comparison of tooth preparation by naked eyes and a microscope, and comparison of different designs of microscopic minimally invasive tooth preparation techniques. Furthermore, a clinical protocol for microscopic minimally invasive tooth preparation based on target restorative space guide plate has been put forward and new insights on the quantity and shape of microscopic minimally invasive tooth preparation has been provided.
journal_name
Int J Oral Scijournal_title
International journal of oral scienceauthors
Yu H,Zhao Y,Li J,Luo T,Gao J,Liu H,Liu W,Liu F,Zhao K,Liu F,Ma C,Setz JM,Liang S,Fan L,Gao S,Zhu Z,Shen J,Wang J,Zhu Z,Zhou Xdoi
10.1038/s41368-019-0057-ysubject
Has Abstractpub_date
2019-10-02 00:00:00pages
31issue
3eissn
1674-2818issn
2049-3169pii
10.1038/s41368-019-0057-yjournal_volume
11pub_type
杂志文章abstract::All-trans retinoic acid (ATRA) inhibits matrix metalloproteinase (MMP)-2 and MMP-9 in synovial fibroblasts, skin fibroblasts, bronchoalveolar lavage cells and cancer cells, but activates MMP-9 in neuroblast and leukemia cells. Very little is known regarding whether ATRA can activate or inhibit MMPs in human dental pul...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2013.63
更新日期:2014-09-01 00:00:00
abstract::Both bone morphogenetic protein 2 (BMP2) and the wingless-type MMTV integration site (WNT)/β-catenin signalling pathway play important roles in odontoblast differentiation and dentinogenesis. Cross-talk between BMP2 and WNT/β-catenin in osteoblast differentiation and bone formation has been identified. However, the ro...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2015.7
更新日期:2015-06-26 00:00:00
abstract::Bone defects caused by trauma, tumour resection, infection and congenital deformities, together with articular cartilage defects and cartilage-subchondral bone complex defects caused by trauma and degenerative diseases, remain great challenges for clinicians. Novel strategies utilising cell sheet technology to enhance...
journal_title:International journal of oral science
pub_type: 杂志文章,评审
doi:10.1038/s41368-019-0050-5
更新日期:2019-05-21 00:00:00
abstract::This in vitro study aims to evaluate the crystal and surface microstructure of dental enamel after cold-light bleaching treatment. Twelve sound human premolars were cross-split into four specimens, namely, mesio-buccal (Group LP), disto-buccal (Group P), mesio-lingual (Group NP) and disto-lingual (Group L) specimens. ...
journal_title:International journal of oral science
pub_type: 杂志文章,随机对照试验
doi:10.1038/ijos.2012.70
更新日期:2012-12-01 00:00:00
abstract::The aim of this study was to evaluate the biological efficacy of a unique perpendicular protrusion of type-I collagen (Col-I) from TiO2 nanotubes (NT-EPF surface). We hypothesized that the NT-EPF surface would play bifunctional roles in stimulating platelet-mediated fibroblast recruitment and anchoring fibroblast-deri...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/s41368-020-00103-3
更新日期:2020-12-30 00:00:00
abstract::Dentin matrix metalloproteinases (MMPs) are a family of host-derived proteolytic enzymes trapped within mineralized dentin matrix, which have the ability to hydrolyze the organic matrix of demineralized dentin. After bonding with resins to dentin there are usually some exposed collagen fibrils at the bottom of the hyb...
journal_title:International journal of oral science
pub_type: 杂志文章,评审
doi:10.4248/IJOS.09044
更新日期:2009-12-01 00:00:00
abstract::Halitosis, bad breath or oral malodour are all synonyms for the same pathology. Halitosis has a large social and economic impact. For the majority of patients suffering from bad breath, it causes embarrassment and affects their social communication and life. Moreover,halitosis can be indicative of underlying diseases....
journal_title:International journal of oral science
pub_type: 杂志文章,评审
doi:10.1038/ijos.2012.39
更新日期:2012-06-01 00:00:00
abstract:AIM:The purpose of this study is to compare the effects of the two clutches on recording the condylar movement. METHODOLOGY:Ten subjects (6 women, 4 men; mean age 25.4 years) participated in the study. The mandibular movement, sagittal condylar inclination angle, and transversal condylar inclination angle of each subj...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.4248/IJOS10071
更新日期:2010-12-01 00:00:00
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journal_title:International journal of oral science
pub_type: 杂志文章,随机对照试验
doi:10.1038/ijos.2013.83
更新日期:2014-03-01 00:00:00
abstract:AIM:To evaluate the effect of single or dual field irradiation (IR) with the same dose on damage to miniature pig parotid glands. METHODOLOGY:Sixteen miniature pigs were divided into two IR groups (n=6) and a control group (n=4). The irradiation groups were subjected to 20 Gy X-radiation to one parotid gland using sin...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.4248/ijos.08001
更新日期:2009-03-01 00:00:00
abstract::A previous study demonstrated that alexidine has greater affinity for the major virulence factors of bacteria than chlorhexidine. The aim of this study was to compare the antimicrobial activity of 1% alexidine with that of 2% chlorhexidine using Enterococcus faecalis-infected dentin blocks. Sixty bovine dentin blocks ...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2013.11
更新日期:2013-03-01 00:00:00
abstract::The aim of the present real time in vivo micro-computed tomography (µCT) and histologic experiment was to assess the efficacy of guided bone regeneration (GBR) around standardized calvarial critical size defects (CSD) using bone marrow-derived mesenchymal stem cells (BMSCs), and collagen membrane (CM) with and without...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2015.34
更新日期:2016-03-30 00:00:00
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journal_title:International journal of oral science
pub_type: 杂志文章,评审
doi:10.1038/s41368-019-0062-1
更新日期:2019-10-01 00:00:00
abstract::This study aimed to compare epithelial cells derived from human embryonic stem cells (hESCs) to human ameloblast-lineage cells (ALCs), as a way to determine their potential use as a cell source for ameloblast regeneration. Induced by various concentrations of bone morphogenetic protein 4 (BMP4), retinoic acid (RA) and...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2013.14
更新日期:2013-03-01 00:00:00
abstract::Secondary caries due to biofilm acids is a primary cause of dental composite restoration failure. To date, there have been no reports of dental composites that can repel protein adsorption and inhibit bacteria attachment. The objectives of this study were to develop a protein-repellent dental composite by incorporatin...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2014.77
更新日期:2015-06-26 00:00:00
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journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2014.49
更新日期:2015-06-26 00:00:00
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journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2017.46
更新日期:2017-12-01 00:00:00
abstract::Bacterial biofilms can be viewed as a specific type of persistent bacterial infection. After initial invasion, microbes can attach to living and non-living surfaces, such as prosthetics and indwelling medical devices, and form a biofilm composed of extracellular polysaccharides, proteins, and other components. In host...
journal_title:International journal of oral science
pub_type: 杂志文章,评审
doi:10.4248/IJOS11022
更新日期:2011-04-01 00:00:00
abstract::Sites of implantation with compromised biology may be unable to achieve the required level of angiogenic and osteogenic regeneration. The specific function and contribution of different cell types to the formation of prevascularized, osteogenic networks in co-culture remains unclear. To determine how bone marrow-deriv...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2016.39
更新日期:2016-12-16 00:00:00
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journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.4248/IJOS11077
更新日期:2011-10-01 00:00:00
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journal_title:International journal of oral science
pub_type: 杂志文章,评审
doi:10.1038/s41368-020-0082-x
更新日期:2020-04-30 00:00:00
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journal_title:International journal of oral science
pub_type: 杂志文章,评审
doi:10.1038/ijos.2017.1
更新日期:2017-03-01 00:00:00
abstract::The aim of the study was a determination of the levels of nitric oxide (NO) and its biological markers such as malonyldialdehyde (MDA) and nitrotyrosine in the serum of patients with squamous cell carcinoma (SCC) of the oral cavity and identification of the relationships between NO and those markers. These studies wer...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2013.59
更新日期:2013-09-01 00:00:00
abstract::The presence of a large palatal or maxillary defect after partial or total maxillectomy for tumor, trauma or congenital deformation poses a challenge to prosthodontists, particularly when the use of an implant cannot be considered. This case report described the use of an air valve in a hollow silicone obturator to ma...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2012.22
更新日期:2012-06-01 00:00:00
abstract::Drug-induced gingival overgrowth (DIGO) is recognized as a side effect of nifedipine (NIF); however, the underlying molecular mechanisms remain unknown. In this study, we found that overexpressed miR-4651 inhibits cell proliferation and induces G0/G1-phase arrest in gingival mesenchymal stem cells (GMSCs) with or with...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/s41368-020-0076-8
更新日期:2020-03-31 00:00:00
abstract::The root is crucial for the physiological function of the tooth, and a healthy root allows an artificial crown to function as required clinically. Tooth crown development has been studied intensively during the last few decades, but root development remains not well understood. Here we review the root development proc...
journal_title:International journal of oral science
pub_type: 杂志文章,评审
doi:10.1038/ijos.2012.61
更新日期:2012-12-01 00:00:00
abstract::Apoptosis or programmed cell death plays an essential role in chemotherapy-induced tumor cell killing, and inducers of apoptosis are commonly used in cancer therapy. Treatment with Zelkova serrata extracts was performed in human gingival fibroblast (HGF), mouth epidermoid carcinoma cell (KB), lower gingival squamous c...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2012.14
更新日期:2012-06-01 00:00:00
abstract::Retention wires permanently bonded to the anterior teeth are used after orthodontic treatment to prevent the teeth from relapsing to pre-treatment positions. A disadvantage of bonded retainers is biofilm accumulation on the wires, which produces a higher incidence of gingival recession, increased pocket depth and blee...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2014.69
更新日期:2015-03-23 00:00:00
abstract::The oral microbial community is widely regarded as a latent reservoir of antibiotic resistance genes. This study assessed the molecular epidemiology, susceptibility profile, and resistance mechanisms of 35 methicillin-resistant Staphylococcus epidermidis (MRSE) strains isolated from the dental plaque of a healthy huma...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/s41368-020-0079-5
更新日期:2020-05-09 00:00:00
abstract::Osteoporosis is a serious public bone metabolic disease. However, the mechanisms underlying bone loss combined with ageing, which is known as senile osteoporosis, remains unknown. Here we show the detailed phenotype of this disease caused by SIRT6 knock out (KO) in mice. To the best of our knowledge, this is the first...
journal_title:International journal of oral science
pub_type: 杂志文章
doi:10.1038/ijos.2015.57
更新日期:2016-06-30 00:00:00