Abstract:
:Onychomycosis is a chronic fungal infection of the nail that is recalcitrant to treatment. It is unclear why normally effective antifungal therapy results in low cure rates. Evidence suggests that there may be a plethora of reasons that include the limited immune presence in the nail, reduced circulation, presence of commensal microbes, and fungal influence on immune signaling. Therefore, treatment should be designed to address these possibilities and work synergistically with both the innate and adaptive immune responses.
journal_name
J Am Podiatr Med Assocjournal_title
Journal of the American Podiatric Medical Associationauthors
Gupta AK,Carviel J,Shear NHdoi
10.7547/17-080subject
Has Abstractpub_date
2019-09-01 00:00:00pages
374-378issue
5eissn
8750-7315issn
1930-8264journal_volume
109pub_type
杂志文章,评审abstract:BACKGROUND:Falls are a major clinical problem in the hospital setting. This study examined the prevalence of foot pathology and footwear type likely to increase the risk of falls in two subacute-care hospital wards serving elderly patients. METHODS:Two wards of a subacute aged-care hospital were selected for study. Pa...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0970213
更新日期:2007-05-01 00:00:00
abstract::One hundred thirty-two female basketball players were observed for lower-extremity overuse injury between 1993 and 2004. Athletes studied between 1993 and 1996 did not receive foot orthotic devices and composed the control group. The treatment group comprised athletes studied between 1996 and 2004. Athletes in the tre...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0960408
更新日期:2006-09-01 00:00:00
abstract::The authors illustrated a chronic bilateral plantar foot ulcer of several years' duration that was resistant to all forms of conventional therapy, yet was resolved after 13 1/2 weeks of maggot therapy. The contralateral foot ulcer showed no improvement during the same period, despite continual inpatient conventional d...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-85-4-218
更新日期:1995-04-01 00:00:00
abstract::Clinicians have traditionally assessed range of motion of the first metatarsophalangeal and ankle joints in a static position. It is unclear, however, if these measurements accurately reflect functional sagittal plane limitations of these joints during gait. For 50 patients (100 feet), we assessed available dorsiflexi...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0940535
更新日期:2004-11-01 00:00:00
abstract::The authors report digital pressure changes in normal subjects following the 5-min postocclusive reactive hyperemia test. This test increases the sensitivity of using toe pressures to assess the adequacy of blood flow. ...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-81-2-57
更新日期:1991-02-01 00:00:00
abstract::Traditional methods of diagnosing onychomycosis, such as microscopy, histologic staining, and cultures, may not provide the clinician with documentation before initiating antifungal drug therapy. DNA technology now supplies the tools for increased sensitivity, speed, and accuracy in the diagnostic arena by allowing fo...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章,评审
doi:10.7547/0970134
更新日期:2007-03-01 00:00:00
abstract::A review of 12 cases of bony tumors involving the talus is presented. Giant cell tumor was the most common tumor. Malignant tumors should be treated by surgical ablation followed by chemotherapy. There are good results after excision or curettage and bone grafting in the treatment of benign neoplasms. Giant cell tumor...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-84-8-379
更新日期:1994-08-01 00:00:00
abstract::Simultaneous pancreas-kidney transplant (SPKT) is an accepted approach and the treatment of choice in patients with type 1 diabetes with accompanying end-stage renal disease. Charcot's neuroarthropathy of the foot (CN) is a fairly common and devastating complication found in patients with long-standing, mostly uncontr...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/15-037
更新日期:2016-07-01 00:00:00
abstract::Tendinopathy in the presence of gouty arthropathy is relatively common, yet the clinical suspicion for gout involvement in acute tendon pain remains low. A 49-year-old man presented with an acute, tender, erythematous mass to the right posterior heel. A computed tomographic scan was obtained, which revealed a septated...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/18-129
更新日期:2019-07-01 00:00:00
abstract::The author reflects upon his experiences within podiatric medical education and shares his thoughts about the directions podiatric medical education should take before the end of the century. The author envisions a collaborative effort between the practitioners and educators within the profession in areas such as curr...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-82-6-286
更新日期:1992-06-01 00:00:00
abstract::Articular hyaline cartilage is of interest to both the clinician and the basic scientist because of its unique physical and chemical properties which are a consequence of its biochemical composition. Although it is a tissue which is hypocellular, avascular, and also lacks nerves and lymphatics, it is active in synthes...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-85-5-277
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:We sought to show the biomechanical and morphometric properties of flexor hallucis longus (FHL) and flexor digitorum longus (FDL) tendon grafts harvested by specific surgical approaches and to assess the contribution of FHL slips to the long flexor tendons of the toes. METHODS:Thirteen fresh-frozen amputate...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/17-063
更新日期:2019-07-01 00:00:00
abstract::A rare case of closed complete rupture of the flexor hallucis longus tendon with subsequent longitudinal tear of the flexor digitorum longus tendon is reported in a marathon runner. This is also a first case report of flexor hallucis longus transplant with cadaveric posterior tibial tendon allograft. Two minimal incis...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0003-0538-104.5.508
更新日期:2014-09-01 00:00:00
abstract::Osteomyelitis and osteoarthropathy may appear clinically and radiographically similar. Many retrospective and some prospective studies have shown that magnetic resonance imaging provides valuable information about the pathologic basis of disease, specifically in the differentiation of osteomyelitis from osteoarthropat...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章,评审
doi:10.7547/87507315-86-4-164
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:This study examined the success of an admission screen in identifying applicants who will fail Part I or Part II of the Podiatric Boards on the first attempt. METHODS:A logistic regression model was used to predict failure on the Podiatric Boards. RESULTS:The biology Medical College Admission Test (MCAT) s...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1020485
更新日期:2012-11-01 00:00:00
abstract::A device was constructed to assess two-point discrimination in the plantar skin of younger, middle-aged, and older adults. The device consisted of paired filaments, each delivering a tip force of 4.56 log units (equivalent to 3.63 g), at a fixed distance apart. Statistical analysis showed significant differences in tw...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-89-8-383
更新日期:1999-08-01 00:00:00
abstract::Amputation at the level of the ankle joint is a valuable but underused procedure for a variety of conditions affecting the foot and ankle. The procedure provides a comfortable and durable stump that allows the lower-extremity amputee to function with minimal disability. This article reviews the indications for Syme's ...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-92-4-232
更新日期:2002-04-01 00:00:00
abstract::Abstract BACKGROUND: The relationship between hyperglycemia and adverse outcomes following surgery has been widely documented. Long-term glucose control has been recognized as a risk factor for postoperative complications. In the foot and ankle literature, long-term glycemic control as a potential perioperative risk f...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/13-026.1
更新日期:2014-06-24 00:00:00
abstract:BACKGROUND:Maintaining balance is a complex phenomenon that is influenced by a range of sensorimotor factors. Foot posture and mobility may also influence balance and postural sway. Recently, three-dimensional foot scanners have been used to assess foot posture. This tool allows many individuals to be scanned quickly a...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/14-021
更新日期:2015-09-01 00:00:00
abstract::Despite the plethora of information on human gait analysis, its continued use as a clinical tool remains uncertain. Analysis of gait dysfunction has become integral to podiatric medical practice, and, like many specialized fields, it is rapidly changing to meet the needs of the future. Practice in the 21st century is ...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 历史文章,杂志文章
doi:10.7547/0950130
更新日期:2005-03-01 00:00:00
abstract::Heel pain is a complaint frequently encountered in orthopedic clinics that has peculiar symptoms and may have various etiologic causes. Calcaneal spur fracture is an extremely rare cause of heel pain, and only four cases had previously been reported in the English language literature. We present a 45-year-old woman wh...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/17-111
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:An observational study was conducted to assess the prevalence of onychomycosis in clinically suspected diabetic neuropathic patients and to assess the reliability of the diagnosis. METHODS:One hundred successive type 1 and 2 diabetic patients with diabetic neuropathy were followed. Diabetic neuropathy was d...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0980135
更新日期:2009-03-01 00:00:00
abstract::Ciprofloxacin and other fluoroquinolones are commonly used broad-spectrum antimicrobial agents for treating bacterial infections. This class of antibiotic drugs has uncommon adverse effects that include tendonitis, tendon ruptures, and other tendon abnormalities. We describe a patient with spontaneous bilateral comple...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0003-0538-105.2.185
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Onychomycosis is estimated to occur in approximately 10% of the global population, with most cases caused by Trichophyton rubrum. Some persistent onychomycosis is caused by mixed infections of T rubrum and one or more co-infecting nondermatophyte molds (NDMs). In onychomycosis, T rubrum strain types may natu...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/17-201
更新日期:2020-11-01 00:00:00
abstract::Rickets is a pediatric disorder not commonly encountered by physicians in the US. Nevertheless, the podiatric physician should be aware that it persists and may exist in children who initially present with gait disturbances or failure to thrive. By using routine plain film radiography of the child's foot, the podiatri...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-86-6-266
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND:Older people have multiple foot health problems; therefore, nursing staff need to pay attention to the foot care of older people, especially in long-term care and nursing homes. The aim of this study was to investigate the knowledge of nursing staff (n = 16) regarding foot care, their foot-care activities, a...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1010159
更新日期:2011-03-01 00:00:00
abstract::A case report of a wooden toothpick as a foreign body in the foot was presented. Such lesions are visualized poorly, if at all, on standard radiographs, and localization of the foreign body may not be possible. Computed tomography, with its superior soft tissue imaging capabilities, can detect this otherwise radioluce...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-79-9-458
更新日期:1989-09-01 00:00:00
abstract::The evaluation of ulcer size is normally limited to measuring length, width, and depth, and comparing those figures to previously obtained values. These comparisons are grossly inaccurate, and a more representative technique can be used by treating the ulceration as a three-dimensional object. The author proposes seve...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章,评审
doi:10.7547/87507315-85-2-91
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:We assessed the efficacy of customized foot orthotic therapy by comparing reulceration rates, minor amputation rates, and work and daily living activities before and after therapy. Peak plantar pressures and peak plantar impulses were compared with the patients not wearing and wearing their prescribed footwe...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1030281
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Magnetic resonance imaging (MRI) and ultrasonography are used widely for the diagnosis of Morton's neuroma. The aim of this study was to assess the accuracy of these two modalities as diagnostic tools in Morton's neuroma. METHODS:Fifty feet of 47 consecutive patients (39 women and 8 men; mean age, 46 years;...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1020184
更新日期:2012-05-01 00:00:00