A Stealthy Fungal Attack Requires an Equally Clandestine Approach to Onychomycosis Treatment.

Abstract:

:Onychomycosis is a chronic fungal infection of the nail that is recalcitrant to treatment. It is unclear why normally effective antifungal therapy results in low cure rates. Evidence suggests that there may be a plethora of reasons that include the limited immune presence in the nail, reduced circulation, presence of commensal microbes, and fungal influence on immune signaling. Therefore, treatment should be designed to address these possibilities and work synergistically with both the innate and adaptive immune responses.

journal_name

J Am Podiatr Med Assoc

authors

Gupta AK,Carviel J,Shear NH

doi

10.7547/17-080

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

374-378

issue

5

eissn

8750-7315

issn

1930-8264

journal_volume

109

pub_type

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