Survival rate of colon and rectum cancer in Iran: A systematic review and meta-analysis.

Abstract:

:Colorectal cancer is one of the deadliest cancers worldwide. Effective screening, surveillance and prevention can decrease its incidence, mortality and burden. This meta-analysis aims to provide a pooled estimation of 5-year survival rate for colorectal cancer based on topography codes and treatment in Iranian population. A systematic search for literature was done in international and national databases up to July 2018. Twenty-seven studies from 4929 articles met the eligible criteria. The overall pooled 5-year survival rates of colorectal cancer, colon, rectal and sigmoid were 56% (95% CI: 49, 63), 53% (95% CI: 41, 65), 52% (95% CI: 41, 62) and 38% (95% CI: 22, 55), respectively. In addition, 5-year survival rate of colorectal cancer after surgery was 64% (95%CI: 50, 78). Subgroup analysis by type of data source showed significantly higher rate of survival in oncology center (29%) than hospital-based (p=0.005). As a conclusion, low survival rate of colorectal cancer in Iran necessitates effective screening and surveillance strategies to find precancerous polyps and detect early-stage cases with lower stage risk of cancer.

journal_name

Neoplasma

journal_title

Neoplasma

authors

Panahi MH,Panahi H,Mahdavi Hezaveh A,Mansournia MA,Bidhendi Yarandi R

doi

10.4149/neo_2019_190131N92

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

988-994

issue

6

eissn

0028-2685

issn

1338-4317

pii

190131N92

journal_volume

66

pub_type

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