Abstract:
BACKGROUND:In Turkey, pneumococcal conjugated vaccine (PCV) was introduced to the national immunization program as PCV7 in 2008, and was replaced with PCV13 in 2011. The aims of this study were to investigate the effects of PCV13 on nasopharyngeal pneumococcal carriage (NPC) by determining the serotype distribution, and to identify risk factors for carriage, in healthy Turkish children. METHODS:This prospective study was conducted on 500 healthy children aged 0-13 years between April and November 2014. Nasopharyngeal swab samples were taken, and molecular method for capsular serotyping was performed by multiplex PCR. RESULTS:Of 500 children, 43.4% were unvaccinated with a PCV (7- or 13-valent), 56.6% were vaccinated and The NPC rate was found to be 9.8%. Of 49 positive Streptococcus pneumoniae isolates, 26 (53%) were PCV13 vaccine strains (VSs), and 17 (34.7%) were non-VS. Six isolates (12.2%) were not typeable by the method applied. The most common serotypes detected were serotype 3 (18.3%), serotype 19F (14.2%), serotype 6A/B (8.1%), serotype 11A (8.1%), and serotype 15B (8.1%). The total coverage rate of the PCV13 serotypes was 60.4%. CONCLUSION:A significant decrease in carriage rate was detected within three years after the introduction of PCV13 in Turkey. However, the nasopharyngeal carriage of PCV13 strains was found to be interestingly high.
journal_name
J Infect Public Healthjournal_title
Journal of infection and public healthauthors
Kanık Yüksek S,Tezer H,Gülhan B,Özkaya Parlakay A,Güldemir D,Coskun-Ari FF,Bedir Demirdağ T,Kara Uzun A,Kızılgün M,Solmaz S,Kılıç S,Yalınay Çırak M,Baran Aksakal FNdoi
10.1016/j.jiph.2019.10.009subject
Has Abstractpub_date
2020-02-01 00:00:00pages
266-274issue
2eissn
1876-0341issn
1876-035Xpii
S1876-0341(19)30347-8journal_volume
13pub_type
杂志文章abstract::This paper describes a voluntary anonymous survey to investigate the seroprevalence of Hepatitis C (HCV) in children in Glasgow, UK attending a Dental Hospital and the proportion of HCV positive mothers who have a child who is HCV seropositive. The study was undertaken among children and accompanying parents and house...
journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
pub_type: 杂志文章
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2013.11.006
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journal_title:Journal of infection and public health
pub_type: 杂志文章
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
pub_type: 杂志文章
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
doi:10.1016/j.jiph.2018.05.013
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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doi:10.1016/j.jiph.2019.06.006
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2010.09.007
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journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
doi:10.1016/j.jiph.2018.07.004
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2017.05.004
更新日期:2017-01-01 00:00:00
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2011.11.005
更新日期:2012-04-01 00:00:00
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.10.008
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