Sarcopenic obesity: research advances in pathogenesis and diagnostic criteria.

abstract：AIMS:The objective of this study was to examine baseline frailty status (including cognitive deficits) and important clinical outcomes, to inform shared decision-making in older adults receiving transcatheter aortic valve implantation (TAVI). METHODS AND RESULTS:We conducted a prospective, observational study of 82 TA...

journal_title：Aging clinical and experimental research

authors： Skaar E,Øksnes A,Eide LSP,Norekvål TM,Ranhoff AH,Nordrehaug JE,Forman DE,Schoenenberger AW,Hufthammer KO,Kuiper KK,Bleie Ø,Packer EJS,Langørgen J,Haaverstad R,Schaufel MA

更新日期：2020-03-19 00:00:00

abstract：:Senescence of the brain seems to be related to increased levels of free oxygen radical (FOR). FOR may damage macromolecular compounds such as: proteins, lipids, and DNA. In the aging brain, increased FOR levels damage DNA, mitochondrial DNA (mtDNA), and nuclear DNA (nDNA). In DNA they damage single and double strands,...

journal_title：Aging clinical and experimental research

authors： Dorszewska J

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Researchers and policy-makers have recognized that quality of life assessments are essential to better understand the benefits of rehabilitation intervention. The purpose of the study was to examine associations between functional status and satisfaction with community participation for persons with...

journal_title：Aging clinical and experimental research

authors： Ostir GV,Smith PM,Smith D,Ottenbacher KJ

更新日期：2005-02-01 00:00:00

abstract：:Prevention is an important but neglected issue in geriatric medicine. Vaccination plays a major role in prevention of infectious diseases, but its implementation in clinical practice is far from perfect. To improve practice, a group of French experts composed of geriatricians and infectious disease specialists prepare...

journal_title：Aging clinical and experimental research

authors： Belmin J,Bourée P,Camus D,Guiso N,Jeandel C,Trivalle C,Veyssier P

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The palliative prognostic index (PPI) is a commonly used tool to predict the life expectancy in palliative care patients. However, there is no universal cutoff, and the accuracy of different cutoffs varies. Therefore, we conducted this meta-analysis to explore the validity and accuracy of different PPI score...

journal_title：Aging clinical and experimental research

authors： Liu Y,Su L,Wang Y,Liu S,Dong B

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Fragility fracture significantly increases risk of future fracture. The fragility fracture cycle should be disrupted. The secondary fracture prevention is important for the patients with fragility hip fracture. The pharmacotherapy for osteoporosis is important for prevention of new fracture. However, many pa...

journal_title：Aging clinical and experimental research

authors： Wang P,Li Y,Zhuang H,Yu H,Cai S,Xu H,Chen Z,Lin J,Yao X

更新日期：2019-10-01 00:00:00

abstract：:Antioxidative/oxidative balance is one of the important factors for homeostasis. Antioxidative systems which protect from peroxidative damage are supposed to be under the influence of steroid hormones. The implications of this influence are age and gender as well as tissue dependent alterations in antioxidative enzyme...

journal_title：Aging clinical and experimental research

authors： Giergiel M,Lopucki M,Stachowicz N,Kankofer M

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Patient navigation improves outcomes in various clinical contexts, but has not been evaluated in secondary fracture prevention. METHODS:We retrospectively reviewed charts of patients, age 50 + from April to October, 2016 hospitalized with fragility fracture contacted by a patient navigator. Patients were ...

journal_title：Aging clinical and experimental research

authors： Jia KQ,Southerland L,Phieffer L,Stephens JA,Ing SW

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Despite the use of the new generation P2Y12 inhibitors (Ticagrelor and Prasugrel) with aspirin is the recommended therapy in acute NSTE-ACS patients, their current use in clinical practice remains quite low and might be related, among several variables, with increased comorbidity burden. We aimed to assess...

journal_title：Aging clinical and experimental research

authors： Aboal J,Llaó I,García García C,Sans-Roselló J,Sambola A,Andrea R,Tomás C,Bonet G,Ariza-Solé A,Viñas D,Oliveras Vilà T,Montero S,Cantalapiedra J,Pujol-López M,Hernández I,Pérez-Rodriguez M,Loma-Osorio P,Sánchez-Salado JC

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Advances such as passive monitoring technology (PMT), which provides holistic supervision of chronically ill and elderly patients, enable and support improved monitoring and observation, thus empowering the growing population of older adults to live more independently while lowering health care expenses. AI...

journal_title：Aging clinical and experimental research

authors： Schneider JE,Cooper J,Scheibling C,Parikh A

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Assessment of physical frailty is important among elderly with severe aortic stenosis (AS) when considering treatment. AIMS:We aimed to: (1) investigate the prevalence of physical frailty in older people with severe AS and (2) examine factors related to physical frailty. METHODS:A total of 125 consecutive ...

journal_title：Aging clinical and experimental research

authors： Fukui S,Kawakami M,Otaka Y,Ishikawa A,Mizuno K,Tsuji T,Hayashida K,Inohara T,Yashima F,Liu M

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To describe the effect of testosterone replacement therapy (TRT) on the brain activity of two demented, hypogonadal male patients with early and late-stage Alzheimer's disease (AD), respectively. METHODS:We describe the clinical and positron emission tomography (PET) findings for two individuals, one with ea...

journal_title：Aging clinical and experimental research

authors： Tan RS

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Higher age is associated with reduced physical capability in the general population. The role of age and gender for physical performance in older adults who exercises regularly is, however, not clear, and there is also a lack of recommendations for outcomes to address physical performance for this population...

journal_title：Aging clinical and experimental research

authors： Tangen GG,Robinson HS

更新日期：2020-02-01 00:00:00

abstract：:Physical frailty (PF) and sarcopenia are major health issues in geriatric populations, given their high prevalence and association with several adverse outcomes. Nevertheless, the lack of an univocal operational definition for the two conditions has so far hampered their clinical implementation. Existing definitional ...

journal_title：Aging clinical and experimental research

authors： Calvani R,Marini F,Cesari M,Tosato M,Picca A,Anker SD,von Haehling S,Miller RR,Bernabei R,Landi F,Marzetti E,SPRINTT Consortium.

更新日期：2017-02-01 00:00:00

abstract：INTRODUCTION:Endogenous brain-derived neurotrophic factor (BDNF) is thought to be protective against the neurodegeneration seen in Parkinson's disease (PD), and is thought to increase during exercise. This has been proposed as a possible mechanism by which exercise improves outcomes for people with PD. We conducted a p...

journal_title：Aging clinical and experimental research

authors： O'Callaghan A,Harvey M,Houghton D,Gray WK,Weston KL,Oates LL,Romano B,Walker RW

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of nutrition combined physical exercise interventions on age-related cognitive decline by a systematic review and meta-analysis. METHODS:We searched 9 databases, including PubMed, EMbase, The Cochrane Library, Web of Science, Science Direct, China National Knowledge Infrastructure (CNK...

journal_title：Aging clinical and experimental research

authors： Liu T,Li N,Hou Z,Liu L,Gao L,Wang L,Tan J

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND AND AIMS:Osteoporosis and fall fractures are increasing problems amongst the elderly. The aim of this study was to explore whether combined population-based and individual interventions directed at risk factors for osteoporosis and falls result in behavioral changes in an elderly population. METHODS:A quasi...

journal_title：Aging clinical and experimental research

authors： Grahn Kronhed AC,Blomberg C,Löfman O,Timpka T,Möller M

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND AIMS:In Italy there is a paucity of empirical data on practices concerning end-of-life decisions (ELDs) in geriatrics. We aimed to investigate the frequency and characteristics of ELDs made by Italian physicians and nurses in the geriatric setting. METHODS:In 2009, an anonymous questionnaire was sent to...

journal_title：Aging clinical and experimental research

authors： Giantin V,Siviero P,Simonato M,Iasevoli M,Pengo V,Andrigo M,Storti M,Valentini E,Pegoraro R,Maggi S,Crepaldi G,Manzato E

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:In addition to the normal process of ageing, frailty, defined as a geriatric syndrome, is becoming more prevalent. Around 10% of people over 65 years and 25-50% of those aged over 85 years are frail. Frail elderly are more vulnerable to external stressors and have an increased risk of adverse health outcomes...

journal_title：Aging clinical and experimental research

authors： Windhaber T,Koula ML,Ntzani E,Velivasi A,Rizos E,Doumas MT,Pappas EE,Onder G,Vetrano DL,Roudriguez Laso A,Roudriguez Manjas L,Illario M,Roller-Wirnsberger RE,ADVANTAGE JA WP8 group.

更新日期：2018-12-01 00:00:00

abstract：:Uncountable health care organizations, clinicians, and individuals are striving to prevent obesity and the many chronic medical conditions linked to it by advocating a healthy lifestyle that includes measures such as reducing dietary calorie intake (i.e., calorie restriction = CR and intermittent fasting = IF) or limi...

journal_title：Aging clinical and experimental research

authors： Veronese N,Reginster JY

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Identification of predictive factors on institutionalization provides the basis for the development and application of preadmission assessment. There is a lack of evidence for predictors of institutionalization for older people. AIMS:To examine the effect of predictive factors on institutionalization in hom...

journal_title：Aging clinical and experimental research

authors： Salminen M,Vire J,Viikari L,Vahlberg T,Isoaho H,Lehtonen A,Viitanen M,Arve S,Eloranta S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Cognitive impairment is common among stroke survivors. However, there is controversy on the role of the stroke itself or the associated subcortical damage in post-stroke cognitive decline. AIM:To assess the independent contribution and the interaction of age, the stroke itself and diffuse subcortical damage...

journal_title：Aging clinical and experimental research

authors： Del Brutto OH,Mera RM,Zambrano M,Lama J

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Although nutritional status plays an important part in the physical performance and disability of older people, this relationship has been little studied in developing countries. AIMS:A study on the effects of nutritional status on the physical performance and functional status of elderly people living in r...

journal_title：Aging clinical and experimental research

authors： Tramontano A,Veronese N,Giantin V,Manzato E,Rodriguez-Hurtado D,Trevisan C,De Zaiacomo F,Sergi G

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND AIMS:An accurate diagnosis of sarcopenia is required. The aim of this study is to correlate the results of two methods to define sarcopenia using cross sectional body composition data, with actual loss of fat free mass. METHODS:Healthy older subjects (926 females and 381 males aged 70 years or more) and...

journal_title：Aging clinical and experimental research

authors： Bunout D,de la Maza MP,Barrera G,Leiva L,Gattas V,Hirsch S

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Squamous cell carcinoma (SCC) of the oral tongue is one of the most frequent head and neck cancers. The over-70-year age group is the fastest growing segment of the population. Age, however, is not considered a prognostic factor in oral tongue SCC. This study investigated the clinical and histopatho...

journal_title：Aging clinical and experimental research

authors： Soudry E,Preis M,Hod R,Hamzany Y,Hadar T,Bahar G,Sternov Y,Shpitzer T

更新日期：2011-06-01 00:00:00

abstract：:We present a 61-year-old man with marked peripheral blood eosinophilia, feature of hypereosinophilic syndrome, that later evolved into acute lymphocytic leukemia (ALL-L2). Initially the patient suffered from significant complications related to eosinophilic toxicity, including large urticarial hyperpigmented plaques, ...

journal_title：Aging clinical and experimental research

authors： Song G,Liu H,Sun F,Gu L,Wang S

更新日期：2012-10-01 00:00:00

abstract：:The purpose of this study was to evaluate the relationship between 3 eNOS gene polymorphisms and training status (TS) in affecting plasma nitrite concentration (NO2) in normotensive adults over 50 years old. Resting blood pressure (BP) was measured in all participants (n = 101). Plasma was taken to analyze: lipid prof...

journal_title：Aging clinical and experimental research

authors： da Silva RF,Sertório JT,Lacchini R,Trapé AA,Tanus-Santos JE,Rush JW,Amaral SL,Zago AS

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Influence of cognitive intervention programs on brain activity has not been enough explored. AIMS:The aims of the present study were to clarify changes in brain activity from a cognitive intervention program utilizing the board game "Go" and to examine the relationship between brain activity and the acquisi...

journal_title：Aging clinical and experimental research

authors： Iizuka A,Ishii K,Wagatsuma K,Ishibashi K,Onishi A,Tanaka M,Suzuki H,Awata S,Fujiwara Y

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Oxidative stress has been considered one of the causes of aging. For this reason, treatments based on antioxidants or those capable of increasing endogenous antioxidant activity have been taken into consideration to delay aging or age-related disease progression. AIM:In this paper, we determine if resveratr...

journal_title：Aging clinical and experimental research

authors： Tung BT,Rodriguez-Bies E,Thanh HN,Le-Thi-Thu H,Navas P,Sanchez VM,López-Lluch G

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Falls among the elderly are often associated with walking on uneven ground. Obstacle negotiation requires both postural reaction strategies and anticipatory strategies which may be impaired with age. Anticipatory strategies are necessary in many daily living situations such as crossing the street and negotia...

journal_title：Aging clinical and experimental research

authors： Laessoe U,Voigt M

更新日期：2013-06-01 00:00:00