Abstract：
:This retrospective study was aimed to compare the safety and efficacy of the Direct Flow Medical (DFM) valve with the more established Sapien 3 (S3) valve in transfemoral TAVI in high-risk aortic stenosis (AS) patients. Between February 2014 and August 2016, 99 and 68 patients had the S3 and DFM valves at our center, respectively. The device success rate was statistically similar among the S3 and DFM groups (p = 0.15). The overall post-procedural complication rate was similar between the two groups (p = 0.4). The procedural time was significantly shorter in the S3 group (p < 0.001) and the post-procedure peak pressure gradient (p < 0.001) was significantly higher in the DFM group. However, the frequency of valvular or paravalvular leaks was similar between both valve groups. We found no significant differences in terms of safety between the DFM and S3 valves. This study confirms the safety and efficacy of the DFM valve in high-risk AS patients.
journal_name
J Cardiovasc Transl Resjournal_title
Journal of cardiovascular translational researchauthors
Gamal AS,Akleh S,Zaman A,Das R,Abushouk AI,Edwards Rdoi
10.1007/s12265-019-09948-4subject
Has Abstractpub_date
2020-10-01 00:00:00pages
790-795issue
5eissn
1937-5387issn
1937-5395pii
10.1007/s12265-019-09948-4journal_volume
13pub_type
杂志文章abstract：:Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy with substantial heterogeneity in phenotypic expression and clinical course. Traditionally, two-dimensional echocardiography has been the easiest and most reliable technique for establishing a diagnosis of HCM. However, cardiovascular magnetic...
journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-009-9136-3
更新日期：2009-12-01 00:00:00
abstract：:Non-invasive means of evaluating appropriate cardiac unloading remain to be established. We hypothesized that myocardial deformation assessed by echocardiographic speckle-tracking strain analysis can reliably estimate the degree of left ventricular (LV) unloading under mechanical circulatory support. A total of 24 Yor...
journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
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更新日期：2019-04-01 00:00:00
abstract：:The pathophysiological abnormalities associated with increased arterial stiffness and/or abnormal pressure wave reflection may play crucial roles in increasing the risk of development of cardiovascular events. On the other hand, prehypertension, defined as a systolic blood pressure of 120-139 and/or a diastolic blood ...
journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-011-9345-4
更新日期：2012-06-01 00:00:00
abstract：:The increase in cardiovascular disease and metabolic syndrome incidence following the onset of menopause has highlighted the role of estrogen as a cardiometabolic protective agent. Specifically regarding the heart, estrogen induced an improvement in cardiac function, preserved calcium homeostasis, and inhibited the mi...
journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
doi：10.1007/s12265-016-9675-3
更新日期：2016-02-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 已发布勘误
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更新日期：2020-02-01 00:00:00
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journal_title：Journal of cardiovascular translational research
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
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更新日期：2010-06-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
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更新日期：2017-04-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-010-9203-9
更新日期：2010-10-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
doi：10.1007/s12265-020-10068-7
更新日期：2020-08-28 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-015-9608-6
更新日期：2015-02-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-016-9682-4
更新日期：2016-06-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
doi：10.1007/s12265-020-10054-z
更新日期：2020-06-26 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-012-9368-5
更新日期：2012-08-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-010-9168-8
更新日期：2010-06-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
doi：10.1007/s12265-019-09936-8
更新日期：2020-08-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
doi：10.1007/s12265-017-9783-8
更新日期：2018-02-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-020-10087-4
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,多中心研究
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journal_title：Journal of cardiovascular translational research
pub_type： 历史文章,杂志文章,实务指引,评审
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,多中心研究
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更新日期：2014-08-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
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更新日期：2013-06-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-007-9005-x
更新日期：2008-03-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
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更新日期：2020-06-22 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,随机对照试验
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更新日期：2011-02-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-013-9472-1
更新日期：2013-08-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章,评审
doi：10.1007/s12265-012-9442-z
更新日期：2013-06-01 00:00:00
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journal_title：Journal of cardiovascular translational research
pub_type： 杂志文章
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更新日期：2020-03-24 00:00:00
