Correction to: Measles virus hemagglutinin triggers intracellular signaling in CD150-expressing dendritic cells and inhibits immune response.

abstract：:A classical function of C1q is to bind immune complexes and initiate complement activation producing membrane lytic complexes, opsonins and anaphylatoxins. This classical pathway of complement activation is also elicited when C1q binds some other ligands. Besides complement activation, C1q also regulates cell differen...

journal_title：Cellular & molecular immunology

authors： Lu JH,Teh BK,Wang Ld,Wang YN,Tan YS,Lai MC,Reid KB

更新日期：2008-02-01 00:00:00

abstract：:The human immunodeficiency virus-1 (HIV-1) envelope protein gp120 is the major contributor to the pathogenesis of HIV-associated neurocognitive disorder (HAND). Neuroinflammation plays a pivotal role in gp120-induced neuropathology, but how gp120 triggers neuroinflammatory processes and subsequent neuronal death remai...

journal_title：Cellular & molecular immunology

authors： He X,Yang W,Zeng Z,Wei Y,Gao J,Zhang B,Li L,Liu L,Wan Y,Zeng Q,Gong Z,Liu L,Zhang H,Li Y,Yang S,Hu T,Wu L,Masliah E,Huang S,Cao H

更新日期：2020-03-01 00:00:00

abstract：:The capacity of pluri-potent stem cells to repair the tissues in which stem cells reside holds great promise in development of novel cell replacement therapeutics for treating chronic and degenerative diseases. However, numerous reports show that stem cell therapy, even in an autologous setting, triggers lymphocyte in...

journal_title：Cellular & molecular immunology

authors： Yang XF

更新日期：2007-06-01 00:00:00

abstract：:In human adipose tissue and obesity, miR-99a expression is negatively correlated with inflammation. Therefore, the present study investigated the role of miR-99a in macrophage phenotype activation and adipose tissue inflammation. M2 BMDMs showed a significant increase in miR-99a expression when compared to the M0 and ...

journal_title：Cellular & molecular immunology

authors： Jaiswal A,Reddy SS,Maurya M,Maurya P,Barthwal MK

更新日期：2019-05-01 00:00:00

abstract：:A complex process including both the innate and acquired immune responses results in allograft rejection. Some chemokine receptors and their ligands play essential roles not only for leukocyte migration into the graft but also in facilitating dendritic and T cell trafficking between lymph nodes and the transplant in t...

journal_title：Cellular & molecular immunology

authors： Tan J,Zhou G

更新日期：2005-10-01 00:00:00

abstract：:Previously, we demonstrated that macrophages from thrombospondin 1 (TSP1)-deficient mice have a reduced inflammatory phenotype, suggesting that TSP1 plays a role in macrophage activation. In this study, we determined how TSP1 regulates macrophage function. We found that recombinant or purified platelet human TSP1 trea...

journal_title：Cellular & molecular immunology

authors： Li Y,Qi X,Tong X,Wang S

更新日期：2013-11-01 00:00:00

abstract：:The relationship between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and host immunity is poorly understood. We performed an extensive analysis of immune responses in 32 patients with severe COVID-19, some of whom succumbed. A control population of healthy subjects was included. Patients with COVID-19...

journal_title：Cellular & molecular immunology

authors： Varchetta S,Mele D,Oliviero B,Mantovani S,Ludovisi S,Cerino A,Bruno R,Castelli A,Mosconi M,Vecchia M,Roda S,Sachs M,Klersy C,Mondelli MU

更新日期：2020-10-15 00:00:00

abstract：:MiR-122 is one of the non-coding RNAs which showed its effects on the lipo-metablism, virus infection and HCC forming through regulation of liver gene expression. Its eukaryotic expression vector was constructed by using pSuper which was widely applied in the siRNA expression. The precursor of human miR-122 gene was a...

journal_title：Cellular & molecular immunology

authors： Chen S,Ni M,Yu B,Lv T,Lu M,Gong F

更新日期：2007-12-01 00:00:00

abstract：:Appropriate in vivo control of plasmacytoid dendritic cell (pDC) recruitment and activation is a fundamental requirement for defense against viral infection. During this process, a pivotal event that influences the outcome of viral infection is the production of high levels of type I interferon by pDCs. In particular,...

journal_title：Cellular & molecular immunology

authors： Zhang Z,Wang FS

更新日期：2005-12-01 00:00:00

abstract：:Induction of osteopontin (OPN), a well-known pro-inflammatory molecule, has been observed in acetaminophen (APAP)-induced hepatotoxicity. However, the precise cell source for OPN induction and its role during APAP-induced hepatotoxicity has not been fully explored. By employing a hepatotoxic mouse model induced by APA...

journal_title：Cellular & molecular immunology

authors： Wen Y,Wang C,Gu J,Yu C,Wang K,Sun X,Sun Y,Wu H,Tong Y,Xia Q,Kong X

更新日期：2019-05-01 00:00:00

abstract：:Transplantable experimental tumor models were constructed to study the activities of recombinant human interleukin-15 (rhIL-15) against tumor recurrence and metastasis. The results showed that tumor nodule formation was retarded and tumor growth was inhibited in the subcutaneous tumor model of LA795 lung adenocarcinom...

journal_title：Cellular & molecular immunology

authors： Tang F,Zhao LT,Jiang Y,Ba de N,Cui LX,He W

更新日期：2008-06-01 00:00:00

abstract：:Psoriasis is a chronic inflammatory skin condition that has a fairly wide range of clinical presentations. Plaque psoriasis, which is the most common manifestation of psoriasis, is located on one end of the spectrum, dominated by adaptive immune responses, whereas the rarer pustular psoriasis lies on the opposite end,...

journal_title：Cellular & molecular immunology

authors： Uppala R,Tsoi LC,Harms PW,Wang B,Billi AC,Maverakis E,Michelle Kahlenberg J,Ward NL,Gudjonsson JE

更新日期：2021-02-01 00:00:00

abstract：:Potential crosslinks between inflammation and leukaemia have been discussed for some time, but experimental evidence to support this dogma is scarce. In particular, it is important to understand the mechanisms responsible for potential upregulation of proto-oncogenic growth factor expressions by inflammatory mediators...

journal_title：Cellular & molecular immunology

authors： Wyszynski RW,Gibbs BF,Varani L,Iannotta D,Sumbayev VV

更新日期：2016-01-01 00:00:00

abstract：:Hypoxia is a major characteristic of the tumor microenvironment, and its effects on immune cells are proposed to be important factors for the process of tumor immune escape. It has been reported that hypoxia affects the function of dendritic cells and the antitumor function of T cells. Here we discuss the effects of h...

journal_title：Cellular & molecular immunology

authors： Sun J,Zhang Y,Yang M,Zhang Y,Xie Q,Li Z,Dong Z,Yang Y,Deng B,Feng A,Hu W,Mao H,Qu X

更新日期：2010-01-01 00:00:00

abstract：:The failure of a massive influx of tumor-infiltrating T lymphocytes to eradicate tumor cells in the tumor microenvironment is mainly due to the dysfunction of T cells hyporesponsive to tumors. T-cell exhaustion and senescence induced by malignant tumors are two important dysfunctional states that coexist in cancer pat...

journal_title：Cellular & molecular immunology

authors： Zhao Y,Shao Q,Peng G

更新日期：2020-01-01 00:00:00

abstract：:Interleukin-22 (IL-22) is a recently identified T cell-derived cytokine whose biological significance remains obscure. Previously, we have shown that IL-22 plays a protective role in T cell-mediated hepatitis induced by Concanavalin A (Con A), acting as a survival factor for hepatocytes. In the present paper, we demon...

journal_title：Cellular & molecular immunology

authors： Pan H,Hong F,Radaeva S,Gao B

更新日期：2004-02-01 00:00:00

abstract：:Organ transplantation is an effective therapeutic tool for treating many terminal diseases. However, one of the biggest challenges of transplantation is determining how to achieve the long-term survival of the allogeneic or xenogeneic transplant by, for example, preventing transplant rejection. In the current study, C...

journal_title：Cellular & molecular immunology

authors： Zhao X,Zhang K,Daniel P,Wisbrun N,Fuchs H,Fan H

更新日期：2019-06-01 00:00:00

abstract：:To elucidate the structures of SLA-DR (swine leukocyte antigen DR) genes of three Chinese pig strains (Gz, Bm and Yn), the SLA-DRA and SLA-DRB cDNA were amplified by RT-PCR and subjected to determine the sequences. The whole structures of SLA-DRA alleles are identical among three strains, consisting of 759 nucleotides...

journal_title：Cellular & molecular immunology

authors： Chen F,Xie J,Zhou Y,Li N,Chou KY

更新日期：2004-06-01 00:00:00

abstract：:Using a newly generated monoclonal antibody (2E6) against human B7-H3, we explored the expression of the molecule on dendritic cells derived from monocytes (Mo-DCs). Its expression was examined by means of immunostaining and flow cytometric (FCM) analysis. The results showed that B7-H3 was expressed in the course of M...

journal_title：Cellular & molecular immunology

authors： Zhang G,Dong Q,Xu Y,Yu G,Zhang X

更新日期：2005-08-01 00:00:00

abstract：:Viral encephalitis is a devastating disease with high mortality, and survivors often suffer from severe neurological complications. Microglia are innate immune cells of the central nervous system (CNS) parenchyma whose turnover is reliant on local proliferation. Microglia express a diverse range of proteins, which all...

journal_title：Cellular & molecular immunology

authors： Chhatbar C,Prinz M

更新日期：2021-02-01 00:00:00

abstract：:Vγ2Vδ2 T (also known as Vγ9Vδ2 T) cells exist only in primates, and in humans represent a major γδ T-cell sub-population in the total population of circulating γδ T cells. Results from recent studies suggest that while (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP) phosphoantigen from Mycobacterium tuberculos...

journal_title：Cellular & molecular immunology

authors： Chen ZW

更新日期：2013-01-01 00:00:00

abstract：:Epigenetic modifications to histones dictate the differentiation of naïve CD4+ T cells into different subsets of effector T helper (TH) cells. The histone methyltransferase enhancer of zeste homolog 2 (EZH2) has been implicated in the mechanism regulating the differentiation of TH1, TH2 and regulatory T (Treg) cells. ...

journal_title：Cellular & molecular immunology

authors： Chen X,Cao G,Wu J,Wang X,Pan Z,Gao J,Tian Q,Xu L,Li Z,Hao Y,Huang Q,Wang P,Xiao M,Xie L,Tang S,Liu Z,Hu L,Tang J,He R,Wang L,Zhou X,Wu Y,Chen M,Sun B,Zhu B,Huang J,Ye L

更新日期：2020-03-01 00:00:00

abstract：:Immunoglobulins (Igs) are known to be synthesized and secreted only by B lymphocytes. Class switch recombination (CSR) is a key event that enables B cells to express Igs, and one of the crucial steps for CSR initiation is the germline transcription of Ig genes. Surprisingly, recent studies have demonstrated that the I...

journal_title：Cellular & molecular immunology

authors： Duan Z,Zheng H,Xu S,Jiang Y,Liu H,Li M,Hu D,Li W,Bode AM,Dong Z,Cao Y

更新日期：2014-03-01 00:00:00

abstract：:Neonates are at increased risk of viral encephalopathies that can result in neurological dysfunction, seizures, permanent disability and even death. The neurological damage results from the combined effect of the virus and the immune response it elicits, thus finding tools to facilitate viral clearance from central ne...

journal_title：Cellular & molecular immunology

authors： Ireland DD,Tami C,Pedras-Vasconcelos J,Verthelyi D

更新日期：2017-01-01 00:00:00

abstract：:Circulating monocyte subsets with distinct functions play important roles in hepatitis C virus (HCV) infection. However, the mechanisms have not been well studied. In this study, we analyzed the distributions and phenotypic characteristics of three circulating monocyte subsets-CD14(++)CD16(-), CD14(++)CD16(+) and CD14...

journal_title：Cellular & molecular immunology

authors： Zheng J,Liang H,Xu C,Xu Q,Zhang T,Shen T,Lu F

更新日期：2014-05-01 00:00:00

abstract：:Inflammasomes are important for maintaining intestinal homeostasis, and dysbiosis contributes to the pathology of inflammatory bowel disease (IBD) and increases the risk for colorectal cancer. Inflammasome defects contribute to chronic intestinal inflammation and increase the susceptibility to colitis in mice. However...

journal_title：Cellular & molecular immunology

authors： Ratsimandresy RA,Indramohan M,Dorfleutner A,Stehlik C

更新日期：2017-01-01 00:00:00

abstract：:The unmethylated CpG DNA can prevent spontaneous apoptosis of B cells. However, the precise mechanisms by which CpG DNA blocks apoptosis remain unclear. In this study, we showed B cell apoptosis was significantly inhibited by addition of CpG DNA. Treatment of CpG DNA could reduce the expression of caspase 3, increase ...

journal_title：Cellular & molecular immunology

authors： Zhou Y,Zhen H,Mei Y,Wang Y,Feng J,Xu S,Fu X

更新日期：2009-06-01 00:00:00

abstract：:Despite impressive results obtained in animal models, the clinical use of Fas ligand (FasL) as an anticancer drug is limited by severe toxicity. Systemic toxicity of death ligands may be prevented by using genes encoding membrane-bound death ligands and by targeted transgene expression through either targeted transduc...

journal_title：Cellular & molecular immunology

authors： Liu Z,Wang J,Yin P,Qiu J,Liu R,Li W,Fan X,Cheng X,Chen C,Zhang J,Zhuang G

更新日期：2009-08-01 00:00:00

abstract：:Efficient immune responses against invading pathogens often involve coordination between cells from both the innate and adaptive immune systems. For multiple decades, it has been believed that CD8+ memory T cells and natural killer (NK) cells constantly and uniformly recirculate. Only recently was the existence of non...

journal_title：Cellular & molecular immunology

authors： Sun H,Sun C,Xiao W,Sun R

更新日期：2019-03-01 00:00:00

abstract：:Previous studies have shown that the CC chemokine receptor CCR5 is downregulated on monocyte/macrophage (MO/Mphi) surfaces in head and neck squamous cell carcinoma (HNSCC) patients (stage IIIB). Ligands (RANTES, MIP-1alpha and MIP-1beta) of this chemokine receptor were also secreted in lesser quantity from MO/Mphi of ...

journal_title：Cellular & molecular immunology

authors： Chakraborty K,Bose A,Chakraborty T,Sarkar K,Goswami S,Pal S,Baral R

更新日期：2010-09-01 00:00:00