Quantitative analysis of a micro array anode structured target for hard x-ray grating interferometry.

abstract：:The relative stopping power (RSP) uncertainty is the largest contributor to the range uncertainty in proton therapy. The purpose of this work was to develop a systematic method that yields accurate and patient-specific RSPs by combining (1) pre-treatment x-ray CT and (2) daily proton radiography of the patient. The me...

journal_title：Physics in medicine and biology

authors： Collins-Fekete CA,Brousmiche S,Hansen DC,Beaulieu L,Seco J

更新日期：2017-08-03 00:00:00

abstract：:We discuss the use of terahertz time domain spectroscopy for studies of conformational flexibility and conformational change in biomolecules. Protein structural dynamics are vital to biological function with protein flexibility affecting enzymatic reaction rates and sensory transduction cycling times. Conformational m...

journal_title：Physics in medicine and biology

authors： Markelz A,Whitmire S,Hillebrecht J,Birge R

更新日期：2002-11-07 00:00:00

abstract：:Incorrect prediction of skin dose in external beam radiotherapy (EBR) can have normal tissue complication such as acute skin desquamation and skin necrosis. The absorbed dose of skin should be evaluated within basal layer, placed between the epidermis and dermis layers. However, current treatment planning systems (TPS...

journal_title：Physics in medicine and biology

authors： Cheon BW,Yoo DH,Shin WG,Choi HJ,Park HJ,Kim JI,Min CH

更新日期：2019-08-14 00:00:00

abstract：:The interest in positron emission tomography (PET) and particularly in hybrid integrated PET/CT systems has significantly increased in the last few years due to the improved quality of the obtained images. Nevertheless, one of the most important limits of the PET imaging technique is still its poor spatial resolution ...

journal_title：Physics in medicine and biology

authors： Rapisarda E,Bettinardi V,Thielemans K,Gilardi MC

更新日期：2010-07-21 00:00:00

abstract：:A method of computing theoretical X-ray spectra in the range 30-150 kV is presented. The theoretical spectra are compared with constant potential, high resolution spectra from a tungsten target measured with a Ge(Li) detector, for a range of target angles, tube voltage and filtrations. Above 100 kV the spectra were al...

journal_title：Physics in medicine and biology

authors： Birch R,Marshall M

更新日期：1979-05-01 00:00:00

abstract：:4D cone beam computed tomography (4DCBCT) is an emerging image guidance strategy used in radiotherapy where projections acquired during a scan are sorted into respiratory bins based on the respiratory phase or displacement. 4DCBCT reduces the motion blur caused by respiratory motion but increases streaking artefacts d...

journal_title：Physics in medicine and biology

authors： O'Brien RT,Kipritidis J,Shieh CC,Keall PJ

更新日期：2014-10-07 00:00:00

abstract：:We report on a radiographic measurement of an ex vivo human knee using a grating-based phase-contrast imaging setup and a medical x-ray tube at a tube voltage of 70 kV. The measurement has been carried out using a Talbot-Lau setup that is suitable to achieve a high visibility in the energy regime of medical imaging. I...

journal_title：Physics in medicine and biology

authors： Horn F,Gelse K,Jabari S,Hauke C,Kaeppler S,Ludwig V,Meyer P,Michel T,Mohr J,Pelzer G,Rieger J,Riess C,Seifert M,Anton G

更新日期：2017-08-01 00:00:00

abstract：:Computational phantoms are commonly used in internal radiation dosimetry to assess the amount and distribution pattern of energy deposited in various parts of the human body from different internal radiation sources. Radiation dose assessments are commonly performed on predetermined reference computational phantoms wh...

journal_title：Physics in medicine and biology

authors： Xie T,Kuster N,Zaidi H

更新日期：2017-07-13 00:00:00

abstract：:Dynamic PET image reconstruction is a challenging issue due to the low SNR and the large quantity of spatio-temporal data. We propose a robust state-space image reconstruction (SSIR) framework for activity reconstruction in dynamic PET. Unlike statistically-based frame-by-frame methods, tracer kinetic modeling is inco...

journal_title：Physics in medicine and biology

authors： Tong S,Alessio AM,Kinahan PE,Liu H,Shi P

更新日期：2011-04-21 00:00:00

abstract：:Ultrasound may provide a quantitative technique for the characterization of cartilage changes typical of early osteoarthrosis. In this study, specific changes in bovine articular cartilage were induced using collagenase and chondroitinase ABC, enzymes that selectively degrade collagen fibril network and digest proteog...

journal_title：Physics in medicine and biology

authors： Töyräs J,Rieppo J,Nieminen MT,Helminen HJ,Jurvelin JS

更新日期：1999-11-01 00:00:00

abstract：:Reliable treatment planning of highly conformal scanned ion beam therapy demands accurate tools for the determination and characterization of the individual pencil-like beams building up the integral dose delivery and related mixed radiation field. At present, clinically practicable inverse treatment planning systems ...

journal_title：Physics in medicine and biology

authors： Parodi K,Mairani A,Brons S,Hasch BG,Sommerer F,Naumann J,Jäkel O,Haberer T,Debus J

更新日期：2012-06-21 00:00:00

abstract：:This is a review of the relatively recently developed field of intravascular brachytherapy of coronary arteries. It presents a brief overview of the discipline of coronary angioplasty describing the problem of restenosis and discusses the potential for ionizing radiation to overcome this problem. It examines the vario...

journal_title：Physics in medicine and biology

authors： Fox RA

更新日期：2002-02-21 00:00:00

abstract：:Absorption and emission optical projection tomography (OPT), alternatively referred to as optical computed tomography (optical-CT) and optical-emission computed tomography (optical-ECT), are recently developed three-dimensional imaging techniques with value for developmental biology and ex vivo gene expression studies...

journal_title：Physics in medicine and biology

authors： Fumene Feruglio P,Vinegoni C,Gros J,Sbarbati A,Weissleder R

更新日期：2010-09-21 00:00:00

abstract：:We review the application of fluorescence spectroscopy and elastic-scattering spectroscopy, over the ultraviolet-to-visible wavelength range, to minimally invasive medical diagnostics. The promises and hopes, as well as the difficulties, of these developing techniques are discussed. ...

journal_title：Physics in medicine and biology

authors： Bigio IJ,Mourant JR

更新日期：1997-05-01 00:00:00

abstract：:A new method for correcting simultaneously the attenuation, scatter and resolution effects in SPECT has been developed for the case of a homogeneous medium. It is based on an effective model of the scatter process. This model depends on only four parameters which are determined experimentally and remain independent of...

journal_title：Physics in medicine and biology

authors： Walrand SH,van Elmbt LR,Pauwels S

更新日期：1994-04-01 00:00:00

abstract：:The performance of a light sharing and recirculation mechanism that allows the extraction of depth of interaction (DOI) are investigated in this paper, with a particular focus on timing. In parallel, a method to optimize the coincidence time resolution (CTR) of PET detectors by use of the DOI information is proposed a...

journal_title：Physics in medicine and biology

authors： Pizzichemi M,Polesel A,Stringhini G,Gundacker S,Lecoq P,Tavernier S,Paganoni M,Auffray E

更新日期：2019-08-07 00:00:00

abstract：:The artificial urinary sphincter should be long enough to prevent strangulation effects of the urethral tissue and short enough to avoid the improper dissection of the surrounding tissue. To optimize the sphincter length, the empirical three-parameter urethra compression model is proposed based on the mechanical prope...

journal_title：Physics in medicine and biology

authors： Marti F,Leippold T,John H,Blunschi N,Müller B

更新日期：2006-03-07 00:00:00

abstract：:The purpose of this study was the characterization of local magnetic susceptibility deviations by spectral analysis of their induced magnetic field inhomogeneities. Magnetic resonance spectra and related signal decay curves of local susceptibility deviations were simulated for different volume fractions and compositio...

journal_title：Physics in medicine and biology

authors： Seppenwoolde JH,van Zijtveld M,Bakker CJ

更新日期：2005-01-21 00:00:00

abstract：:In this study, an induced electric field in a human body is evaluated for the magnetic field leaked from a wireless power transfer system for charging an electrical vehicle. The magnetic field from the wireless power transfer system is modelled computationally, and its effectiveness is confirmed by comparison with the...

journal_title：Physics in medicine and biology

authors： Laakso I,Hirata A

更新日期：2013-11-07 00:00:00

abstract：:In radiation therapy, a plan is robust if the calculated and the delivered dose are in agreement, even in the case of different uncertainties. The current practice is to use safety margins, expanding the clinical target volume sufficiently enough to account for treatment uncertainties. This, however, might not be idea...

journal_title：Physics in medicine and biology

authors： Albertini F,Hug EB,Lomax AJ

更新日期：2011-07-21 00:00:00

abstract：:This study evaluates the performance of the Bruker positron emission tomograph (PET) insert combined with a BioSpec 70/30 USR magnetic resonance imaging (MRI) scanner using the manufacturer acceptance protocol and the NEMA NU 4-2008 for small animal PET. The PET insert is made of 3 rings of 8 monolithic LYSO crystals ...

journal_title：Physics in medicine and biology

authors： Gsell W,Molinos C,Correcher C,Belderbos S,Wouters J,Junge S,Heidenreich M,Vande Velde G,Rezaei A,Nuyts J,Cawthorne C,Cleeren F,Nannan L,Deroose CM,Himmelreich U,González Martínez AJ

更新日期：2020-06-26 00:00:00

abstract：:The purpose of this study was to improve the performance of a small gamma camera, utilizing a NaI(Tl) plate and a 5" position sensitive PMT. We attempted to build a NaI(Tl) plate crystal system which retained all its advantages, while at the same time integrating some of the advantages inherent in an array-type scinti...

journal_title：Physics in medicine and biology

authors： Jeong MH,Choi Y,Chung YH,Song TY,Jung JH,Hong KJ,Min BJ,Choe YS,Lee KH,Kim BT

更新日期：2004-11-07 00:00:00

abstract：:We implemented a hybrid scatter-correction method for 3D PET that combines two scatter-correction methods in a complementary way. The implemented scheme uses a method based on the discrimination of the energy of events (the estimation of trues method (ETM)) and an auxiliary method (the single scatter simulation method...

journal_title：Physics in medicine and biology

authors： Ferreira NC,Trébossen R,Lartizien C,Brulon V,Merceron P,Bendriem B

更新日期：2002-05-07 00:00:00

abstract：:A novel digital x-ray detector has been assembled. The imaging system is based on a phosphor-coated charge-coupled device (CCD) obtained by direct deposition of a gadolinium oxysulphide scintillator onto the detector surface. The modulation transfer function has been measured along the two directions of the digital co...

journal_title：Physics in medicine and biology

authors： Gambaccini M,Taibi A,Del Guerra A,Marziani M,Tuffanelli A

更新日期：1996-12-01 00:00:00

abstract：:Cone-beam computed tomography (CBCT) has been clinically used to verify patient position and to localize the target of treatment in image-guided radiation therapy (IGRT). However, when the chest and the upper abdomen are scanned, respiratory-induced motion blurring limits the utility of CBCT. In order to mitigate this...

journal_title：Physics in medicine and biology

authors： Leng S,Tang J,Zambelli J,Nett B,Tolakanahalli R,Chen GH

更新日期：2008-10-21 00:00:00

abstract：:A method will be described for determining the centre of rotation of a mechanically scanned reflection ultrasound computed tomography system. It is based on the principle of obtaining opposing images of a test object containing many point targets. The method is automatic in the sense that the centre of rotation is cal...

journal_title：Physics in medicine and biology

authors： Jago JR

更新日期：1994-12-01 00:00:00

abstract：:The characteristics of an Elekta Precise treatment machine with a gating interface were investigated. Three detectors were used: a Farmer ionization chamber, a MatriXX ionization chamber array and an in-house, single pulse-measurement ionization chamber (IVC). Measurements were made of dosimetric accuracy, flatness an...

journal_title：Physics in medicine and biology

authors： Evans PM,Symonds-Tayler JR,Colgan R,Hugo GD,Letts N,Sandin C

更新日期：2010-04-21 00:00:00

abstract：:Magnetic resonance-guided radiation therapy (MR-GRT) offers great potential to improve radiation treatment outcomes by providing more accurate and patient-tailored therapy. Despite superior soft tissue contrast in MRI, one of the challenges towards MRI-only workflows is that the process often requires some sort of 'MR...

journal_title：Physics in medicine and biology

authors： Nosrati R,Paudel M,Ravi A,Pejovic-Milic A,Morton G,Stanisz GJ

更新日期：2019-07-16 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) is a neuromodulation scheme where a small current is delivered to the brain via two electrodes attached to the scalp. The electrode design is an important topic, not only as regards efficacy, but also from a safety perspective, as tDCS may be related to skin lesions that ...

journal_title：Physics in medicine and biology

authors： Gomez-Tames J,Sugiyama Y,Laakso I,Tanaka S,Koyama S,Sadato N,Hirata A

更新日期：2016-12-21 00:00:00

abstract：:It is important to assess the viability of extremity soft tissues, as this component is often the determinant of the final outcome of fracture treatment. Microwave tomography (MWT) and sensing might be able to provide a fast and mobile assessment of such properties. MWT imaging of extremities possesses a complicated, ...

journal_title：Physics in medicine and biology

authors： Semenov S,Kellam J,Althausen P,Williams T,Abubakar A,Bulyshev A,Sizov Y

更新日期：2007-09-21 00:00:00