Abstract:
Background:The present study aims to investigate the incidence and risk factors associated with postoperative delirium in patients undergoing spine surgery. Methods:PubMed, EMBASE, Cochrane Library, and Science Citation Index were searched up to August 2019 for studies examining postoperative delirium following spine surgery. Incidence and risk factors associated with delirium were extracted. Odds ratios (OR) and 95% confidence intervals (CI) were calculated for outcomes. The Newcastle-Ottawa Scale (NOS) was used for the study quality evaluation. Results:The final analysis includes a total of 40 studies. The pooled analysis reveals that incidence of delirium is 8%, and there are significant differences for developing delirium in age (OR 1.07; 95% CI 1.04-1.09), age more than 65 (OR 4.77; 95% CI 4.37-5.16), age more than 70 (OR 15.87; 95% CI 6.03-41.73), and age more than 80 (OR 1.91; 95% CI 1.78-2.03) years, male (OR 0.81; 95% CI 0.76-0.86), a history of alcohol abuse (OR 2.11; 95% CI 1.67-2.56), anxiety (OR 1.74; 95% CI 1.04-2.44), congestive heart failure (OR 1.4; 95% CI 1.21-1.6), depression (OR 2.5; 95% CI 1.52-3.49), hypertension (OR 1.12; 95% CI 1.04-1.2), kidney disease (OR 1.41; 95% CI 1.16-1.66), neurological disorder (OR 4.66; 95% CI 4.22-5.11), opioid use (OR 1.86; 95% CI 1.18-2.54), psychoses (OR 2.77; 95% CI 2.29-3.25), pulmonary disease (OR 1.81; 95% CI 1.27-2.35), higher mini-mental state examination (OR 0.7; 95% CI 0.5-0.89), preoperative pain (OR 1.88; 95% CI 1.11-2.64), and postoperative urinary tract infection (OR 5.68; 95% CI 2.41-13.39). Conclusions:A comprehensive understanding of incidence and risk factors of delirium can improve prevention, diagnosis, and management. Risk of postoperative delirium can be reduced based upon identifiable risk factors.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Wu X,Sun W,Tan Mdoi
10.1155/2019/2139834subject
Has Abstractpub_date
2019-11-26 00:00:00pages
2139834eissn
2314-6133issn
2314-6141journal_volume
2019pub_type
杂志文章,meta分析abstract::Elevated levels of resistin and epidermal growth factor receptor (EGFR) facilitate the development of breast cancer, although there are no reports of any correlation between these proteins. This study analyzed 392 human breast cancer tissue specimens and 42 samples of adjacent normal tissue. Rates of positive and stro...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8835398
更新日期:2020-11-28 00:00:00
abstract::Although a history of first-trimester recurrent spontaneous abortion (FRSA) is regarded as a risk factor in antenatal care, the characteristic of subsequent pregnancy outcome is not clearly elucidated. Here, a retrospective analysis was performed on the clinical data of 492 singleton pregnant women. 164 of them with t...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
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abstract::Retinal vein occlusion (RVO) is a common vascular disease of retina; however, the pathomechanism leading to RVO is not yet clear. In general, increasing age, hypertension, arteriosclerosis, diabetes mellitus, dyslipidemia, cardiovascular disorder, and cerebral stroke are systemic risk factors of RVO. However, RVO ofte...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2017/4816527
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abstract::Periodontitis is an inflammatory disease involving complex interactions between oral microorganisms and the host immune response. Understanding the structure of the microbiota community associated with periodontitis is essential for improving classifications and diagnoses of various types of periodontal diseases and w...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3130607
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abstract:Background:It is well known that the programmed intermittent epidural bolus (PIEB) technique effectively provides epidural anesthesia in labor. This randomized double-blind trial compared the postoperative analgesic efficacy of PIEB with that of continuous epidural infusion (CEI) in patients undergoing gynecological su...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
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abstract::Pinelliae Rhizoma Praeparatum Cum Alumine (PRPCA) is useful for eliminating dampness and phlegm in clinical settings, targeting the main mechanisms of insomnia as defined in traditional Chinese medicine. However, little is known regarding the sedative and hypnotic effects of PRPCA. In the present study, we examined th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6198067
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abstract:OBJECTIVE:The purpose of this study was to assess the value of ecological momentary assessment in evaluating physical activity among children, adolescents, and adults. It also determines whether ecological momentary assessment fulfills the criteria of validity, reliability, objectivity, norms, and standardization appli...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/915172
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/309307
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/1962181
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2130594
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/680615
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/172646
更新日期:2014-01-01 00:00:00
abstract::Lung cancer is the leading cause of cancer death worldwide. Adenocarcinoma, the most commonly diagnosed histologic type of lung cancer, is associated with smoking. Cigarette smoke promotes inflammation on the airways, which might be mediated by Th17 cells. This inflammatory environment may contribute to tumor developm...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/430943
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/178064
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/648040
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5739247
更新日期:2019-07-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/2912418
更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/4093435
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8823270
更新日期:2020-10-20 00:00:00
abstract::[This corrects the article DOI: 10.1155/2020/5901962.]. ...
journal_title:BioMed research international
pub_type: 杂志文章,已发布勘误
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更新日期:2020-06-22 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/175025
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/423848
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2019/6274719
更新日期:2019-04-11 00:00:00
abstract::Synthetic lethality (SL) is a novel strategy for anticancer therapies, whereby mutations of two genes will kill a cell but mutation of a single gene will not. Therefore, a cancer-specific mutation combined with a drug-induced mutation, if they have SL interactions, will selectively kill cancer cells. While numerous SL...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/196034
更新日期:2014-01-01 00:00:00
abstract::For the induction of robust humoral and cellular immune responses, a strong rationale exists to use vaccine-adjuvant combinations possessing both immune modulatory and enhanced delivery capabilities. Herein, we evaluated the combination of 2 different adjuvants, a TLR9 agonist, composed of synthetic oligodeoxynucleoti...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/636847
更新日期:2013-01-01 00:00:00
abstract:Background:Oxycodone is a widely used opioid analgesic, which is involved in cancer pain and non-cancer pain. This study is intended to understand the publication characteristics of oxycodone research field and assess the quality of pertinent articles from 1998 to 2017. Methods:Oxycodone-related publications from 1998...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9096201
更新日期:2019-10-31 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3845780
更新日期:2019-12-14 00:00:00
abstract::Polymethylmethacrylate (PMMA) bone cement is a popular bone void filler for vertebroplasty. However, the use of PMMA has some drawbacks, including the material's excessive stiffness, exothermic polymerization, and short handling time. This study aimed to create an ideal modified bone cement to solve the above-mentione...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/7901562
更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/386074
更新日期:2013-01-01 00:00:00