Incidence and Risk Factors for Postoperative Delirium in Patients Undergoing Spine Surgery: A Systematic Review and Meta-Analysis.

Abstract:

Background:The present study aims to investigate the incidence and risk factors associated with postoperative delirium in patients undergoing spine surgery. Methods:PubMed, EMBASE, Cochrane Library, and Science Citation Index were searched up to August 2019 for studies examining postoperative delirium following spine surgery. Incidence and risk factors associated with delirium were extracted. Odds ratios (OR) and 95% confidence intervals (CI) were calculated for outcomes. The Newcastle-Ottawa Scale (NOS) was used for the study quality evaluation. Results:The final analysis includes a total of 40 studies. The pooled analysis reveals that incidence of delirium is 8%, and there are significant differences for developing delirium in age (OR 1.07; 95% CI 1.04-1.09), age more than 65 (OR 4.77; 95% CI 4.37-5.16), age more than 70 (OR 15.87; 95% CI 6.03-41.73), and age more than 80 (OR 1.91; 95% CI 1.78-2.03) years, male (OR 0.81; 95% CI 0.76-0.86), a history of alcohol abuse (OR 2.11; 95% CI 1.67-2.56), anxiety (OR 1.74; 95% CI 1.04-2.44), congestive heart failure (OR 1.4; 95% CI 1.21-1.6), depression (OR 2.5; 95% CI 1.52-3.49), hypertension (OR 1.12; 95% CI 1.04-1.2), kidney disease (OR 1.41; 95% CI 1.16-1.66), neurological disorder (OR 4.66; 95% CI 4.22-5.11), opioid use (OR 1.86; 95% CI 1.18-2.54), psychoses (OR 2.77; 95% CI 2.29-3.25), pulmonary disease (OR 1.81; 95% CI 1.27-2.35), higher mini-mental state examination (OR 0.7; 95% CI 0.5-0.89), preoperative pain (OR 1.88; 95% CI 1.11-2.64), and postoperative urinary tract infection (OR 5.68; 95% CI 2.41-13.39). Conclusions:A comprehensive understanding of incidence and risk factors of delirium can improve prevention, diagnosis, and management. Risk of postoperative delirium can be reduced based upon identifiable risk factors.

journal_name

Biomed Res Int

authors

Wu X,Sun W,Tan M

doi

10.1155/2019/2139834

subject

Has Abstract

pub_date

2019-11-26 00:00:00

pages

2139834

eissn

2314-6133

issn

2314-6141

journal_volume

2019

pub_type

杂志文章,meta分析
  • Combined High Resistin and EGFR Expression Predicts a Poor Prognosis in Breast Cancer.

    abstract::Elevated levels of resistin and epidermal growth factor receptor (EGFR) facilitate the development of breast cancer, although there are no reports of any correlation between these proteins. This study analyzed 392 human breast cancer tissue specimens and 42 samples of adjacent normal tissue. Rates of positive and stro...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/8835398

    authors: Zeng Y,Tang CH,Wang Y,Lu HJ,Huang BF,Wang Q,Shao JK,Jin LL,Wang CQ,Teng LS

    更新日期:2020-11-28 00:00:00

  • Adverse Pregnancy Outcomes of Patients with History of First-Trimester Recurrent Spontaneous Abortion.

    abstract::Although a history of first-trimester recurrent spontaneous abortion (FRSA) is regarded as a risk factor in antenatal care, the characteristic of subsequent pregnancy outcome is not clearly elucidated. Here, a retrospective analysis was performed on the clinical data of 492 singleton pregnant women. 164 of them with t...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2017/4359424

    authors: Yang J,Wang Y,Wang XY,Zhao YY,Wang J,Zhao YY

    更新日期:2017-01-01 00:00:00

  • Mystery of Retinal Vein Occlusion: Vasoactivity of the Vein and Possible Involvement of Endothelin-1.

    abstract::Retinal vein occlusion (RVO) is a common vascular disease of retina; however, the pathomechanism leading to RVO is not yet clear. In general, increasing age, hypertension, arteriosclerosis, diabetes mellitus, dyslipidemia, cardiovascular disorder, and cerebral stroke are systemic risk factors of RVO. However, RVO ofte...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2017/4816527

    authors: Kida T

    更新日期:2017-01-01 00:00:00

  • Composition Analysis and Feature Selection of the Oral Microbiota Associated with Periodontal Disease.

    abstract::Periodontitis is an inflammatory disease involving complex interactions between oral microorganisms and the host immune response. Understanding the structure of the microbiota community associated with periodontitis is essential for improving classifications and diagnoses of various types of periodontal diseases and w...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/3130607

    authors: Chen WP,Chang SH,Tang CY,Liou ML,Tsai SJ,Lin YL

    更新日期:2018-11-15 00:00:00

  • The Efficacy of Programmed Intermittent Epidural Bolus for Postoperative Analgesia after Open Gynecological Surgery: A Randomized Double-Blinded Study.

    abstract:Background:It is well known that the programmed intermittent epidural bolus (PIEB) technique effectively provides epidural anesthesia in labor. This randomized double-blind trial compared the postoperative analgesic efficacy of PIEB with that of continuous epidural infusion (CEI) in patients undergoing gynecological su...

    journal_title:BioMed research international

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2018/6297247

    authors: Satomi S,Kakuta N,Murakami C,Sakai Y,Tanaka K,Tsutsumi YM

    更新日期:2018-05-15 00:00:00

  • Pinelliae Rhizoma Praeparatum Cum Alumine Extract: Sedative and Hypnotic Effects in Mice and Component Compounds.

    abstract::Pinelliae Rhizoma Praeparatum Cum Alumine (PRPCA) is useful for eliminating dampness and phlegm in clinical settings, targeting the main mechanisms of insomnia as defined in traditional Chinese medicine. However, little is known regarding the sedative and hypnotic effects of PRPCA. In the present study, we examined th...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/6198067

    authors: Lin S,Nie B,Song K,Ye R,Yuan Z

    更新日期:2019-04-28 00:00:00

  • Using ecological momentary assessment to evaluate current physical activity.

    abstract:OBJECTIVE:The purpose of this study was to assess the value of ecological momentary assessment in evaluating physical activity among children, adolescents, and adults. It also determines whether ecological momentary assessment fulfills the criteria of validity, reliability, objectivity, norms, and standardization appli...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/915172

    authors: Marszalek J,Morgulec-Adamowicz N,Rutkowska I,Kosmol A

    更新日期:2014-01-01 00:00:00

  • Development and characterization of new monoclonal antibodies against human recombinant CA XII.

    abstract::Carbonic anhydrases (CAs) are enzymes that catalyse the reversible hydration of CO2 to bicarbonate. CA XII is considered a potential biomarker of tumor cells and a promising target for specific therapies. The aim of the current study was to develop new monoclonal antibodies (MAbs) against human recombinant CA XII and ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/309307

    authors: Dekaminaviciute D,Lasickiene R,Parkkila S,Jogaite V,Matuliene J,Matulis D,Zvirbliene A

    更新日期:2014-01-01 00:00:00

  • A Computer-Aided Analysis Method of SPECT Brain Images for Quantitative Treatment Monitoring: Performance Evaluations and Clinical Applications.

    abstract::The objective and quantitative analysis of longitudinal single photon emission computed tomography (SPECT) images are significant for the treatment monitoring of brain disorders. Therefore, a computer aided analysis (CAA) method is introduced to extract a change-rate map (CRM) as a parametric image for quantifying the...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/1962181

    authors: Zheng X,Wei W,Huang Q,Song S,Wan J,Huang G

    更新日期:2017-01-01 00:00:00

  • Tumor-Selective Cytotoxicity of Nitidine Results from Its Rapid Accumulation into Mitochondria.

    abstract::We identified a nitidine- (NTD-) accumulating organelle and evaluated the net cytotoxicity of accumulated NTD. To evaluate tumor cell selectivity of the drug, we evaluated its selective cytotoxicity against 39 human cancer cell lines (JFCR39 panel), and the profile was compared with those of known anticancer drugs. Or...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/2130594

    authors: Iwasaki H,Inafuku M,Taira N,Saito S,Oku H

    更新日期:2017-01-01 00:00:00

  • Improvement of endurance of DMD animal model using natural polyphenols.

    abstract::Duchenne muscular dystrophy (DMD), the most common form of muscular dystrophy, is characterized by muscular wasting caused by dystrophin deficiency that ultimately ends in force reduction and premature death. In addition to primary genetic defect, several mechanisms contribute to DMD pathogenesis. Recently, antioxidan...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/680615

    authors: Sitzia C,Farini A,Colleoni F,Fortunato F,Razini P,Erratico S,Tavelli A,Fabrizi F,Belicchi M,Meregalli M,Comi G,Torrente Y

    更新日期:2015-01-01 00:00:00

  • Role of 99mTc-ECD SPECT in the management of children with craniosynostosis.

    abstract:PURPOSE OF THE REPORT:There is a paucity of data on correlation of various imaging modalities with clinical findings in craniosynostosis. Moreover, no study has specifically reported the role of (99m)Tc-ECD SPECT in a large number of subjects with craniosynostosis. MATERIALS AND METHODS:We prospectively analyzed a coh...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2014/172646

    authors: Barik M,Bajpai M,Das RR,Malhotra A,Panda SS,Sahoo MK,Dwivedi S

    更新日期:2014-01-01 00:00:00

  • LAP TGF-Beta Subset of CD4(+)CD25(+)CD127(-) Treg Cells is Increased and Overexpresses LAP TGF-Beta in Lung Adenocarcinoma Patients.

    abstract::Lung cancer is the leading cause of cancer death worldwide. Adenocarcinoma, the most commonly diagnosed histologic type of lung cancer, is associated with smoking. Cigarette smoke promotes inflammation on the airways, which might be mediated by Th17 cells. This inflammatory environment may contribute to tumor developm...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/430943

    authors: Islas-Vazquez L,Prado-Garcia H,Aguilar-Cazares D,Meneses-Flores M,Galicia-Velasco M,Romero-Garcia S,Camacho-Mendoza C,Lopez-Gonzalez JS

    更新日期:2015-01-01 00:00:00

  • Characterization of morphology and composition of inorganic fillers in dental alginates.

    abstract::Energy dispersive X-ray spectroscopy microanalysis (EDX), scanning electron microscopy (SEM), and Archimedes' Principle were used to determine the characteristics of inorganic filler particles in five dental alginates, including Cavex ColorChange (C), Hydrogum 5 (H5), Hydrogum (H), Orthoprint (O), and Jeltrate Plus (J...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/178064

    authors: Guiraldo RD,Berger SB,Consani RL,Consani S,de Carvalho RV,Lopes MB,Meneghel LL,da Silva FB,Sinhoreti MA

    更新日期:2014-01-01 00:00:00

  • In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor.

    abstract:PURPOSE:Suppressor of cytokine signaling 7 (SOCS7) is a member of the SOCS family and is known to interact with phospholipase Cγ-1 (PLCγ-1), a key downstream mediator of the hepatocyte growth factor (HGF)/C-MET axis. Here, we report our observations of the effect of knocking down SOCS7 gene on the behaviour of breast c...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/648040

    authors: Sasi W,Ye L,Jiang WG,Sharma AK,Mokbel K

    更新日期:2014-01-01 00:00:00

  • Multidrug-resistant Staphylococcus aureus Colonization in Healthy Adults Is more Common in Bhutanese Refugees in Nepal than Those Resettled in Ohio.

    abstract::Although studies have shown that human migration is one of the risk factors for the spread of drug-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA), surveillance studies examining MRSA among refugee populations in the US are lacking. This study aimed to assess the prevalence and molecular...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/5739247

    authors: Kadariya J,Thapaliya D,Bhatta S,Mahatara RL,Bempah S,Dhakal N,Smith TC

    更新日期:2019-07-01 00:00:00

  • Effect of High Dietary Tryptophan on Intestinal Morphology and Tight Junction Protein of Weaned Pig.

    abstract::Tryptophan (Trp) plays an essential role in pig behavior and growth performances. However, little is known about Trp's effects on tight junction barrier and intestinal health in weaned pigs. In the present study, twenty-four (24) weaned pigs were randomly assigned to one of the three treatments with 8 piglets/treatmen...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/2912418

    authors: Tossou MC,Liu H,Bai M,Chen S,Cai Y,Duraipandiyan V,Liu H,Adebowale TO,Al-Dhabi NA,Long L,Tarique H,Oso AO,Liu G,Yin Y

    更新日期:2016-01-01 00:00:00

  • Distinct Epitopes on CD13 Mediate Opposite Consequences for Cell Adhesion.

    abstract::CD13 is a membrane glycoprotein with aminopeptidase activity, expressed on several cell types, including myeloid cells (dendritic cells, monocytes, macrophages, neutrophils, etc.). CD13 participates in several functions such as proteolytic regulation of bioactive peptides, viral receptor, angiogenesis, and tumor metas...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/4093435

    authors: Garay-Canales CA,Licona-Limón I,Ortega E

    更新日期:2018-03-29 00:00:00

  • Downregulated METTL14 Expression Correlates with Breast Cancer Tumor Grade and Molecular Classification.

    abstract::It is unclear whether the methyltransferase-like 14 (METTL14) protein promotes or suppresses cancer growth. We examined the association between METTL14 expression, cancer progression, and patient prognosis in a total of 398 breast cancer tissue specimens. Significantly fewer cancer tissue specimens compared with norma...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/8823270

    authors: Dong XF,Wang Y,Huang BF,Hu GN,Shao JK,Wang Q,Tang CH,Wang CQ

    更新日期:2020-10-20 00:00:00

  • Corrigendum to "The Epidemiology of Hip Fracture among Subjects with Pyogenic Liver Abscess (PLA): A Nationwide Population-Based Study".

    abstract::[This corrects the article DOI: 10.1155/2020/5901962.]. ...

    journal_title:BioMed research international

    pub_type: 杂志文章,已发布勘误

    doi:10.1155/2020/8401548

    authors: Hsu CC,Ko JY,Lin CL,Hsu HC,Chen HT,Lin CC,Kuo SJ

    更新日期:2020-06-22 00:00:00

  • Prenatal Exposure to Sodium Arsenite Alters Placental Glucose 1, 3, and 4 Transporters in Balb/c Mice.

    abstract::Inorganic arsenic (iAs) exposure induces a decrease in glucose type 4 transporter (GLUT4) expression on the adipocyte membrane, which may be related to premature births and low birth weight infants in women exposed to iAs at reproductive age. The aim of this study was to analyze the effect of sodium arsenite (NaAsO2) ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/175025

    authors: Gutiérrez-Torres DS,González-Horta C,Del Razo LM,Infante-Ramírez R,Ramos-Martínez E,Levario-Carrillo M,Sánchez-Ramírez B

    更新日期:2015-01-01 00:00:00

  • Chronic Hypoxia-Induced Microvessel Proliferation and Basal Membrane Degradation in the Bone Marrow of Rats Regulated through the IL-6/JAK2/STAT3/MMP-9 Pathway.

    abstract::Chronic hypoxia (CH) is characterized by long-term hypoxia that is associated with microvessel proliferation and basal membrane (BM) degradation in tissues. The IL-6/JAK2/STAT3/MMP-9 pathway has been described in a variety of human cancers and plays an essential role in microvessel proliferation and BM degradation. Th...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/9204708

    authors: Zhu M,Yang M,Yang Q,Liu W,Geng H,Pan L,Wang L,Ge R,Ji L,Cui S,Li Z

    更新日期:2020-01-23 00:00:00

  • ACE-I/ARB therapy prior to contrast exposure: what should the clinician do?

    abstract::Contrast-induced nephropathy (CIN) is now one of the three leading causes of acute kidney injury in the world. A lot is known about the risk factors of CIN, yet it remains a major cause of morbidity, end stage renal disease, prolonged hospital stay, and increased costs as well as a high mortality. Many patients underg...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/423848

    authors: Kalyesubula R,Bagasha P,Perazella MA

    更新日期:2014-01-01 00:00:00

  • Light Emitting Diode (LED) Phototherapy versus Conventional Phototherapy in Neonatal Hyperbilirubinemia: A Single Blinded Randomized Control Trial from Coastal India.

    abstract::Neonatal hyperbilirubinemia is a common problem with potentiality to cause irreversible brain damage. Reduction of serum bilirubin level is essential to minimize such damage. Compact fluorescent tubes, halogen bulbs, fiber optic blankets, and LEDs are commonly used light sources for phototherapy with varying efficacie...

    journal_title:BioMed research international

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2019/6274719

    authors: Gutta S,Shenoy J,Kamath SP,Mithra P,Baliga BS,Sarpangala M,Srinivasan M

    更新日期:2019-04-11 00:00:00

  • Syn-lethality: an integrative knowledge base of synthetic lethality towards discovery of selective anticancer therapies.

    abstract::Synthetic lethality (SL) is a novel strategy for anticancer therapies, whereby mutations of two genes will kill a cell but mutation of a single gene will not. Therefore, a cancer-specific mutation combined with a drug-induced mutation, if they have SL interactions, will selectively kill cancer cells. While numerous SL...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/196034

    authors: Li XJ,Mishra SK,Wu M,Zhang F,Zheng J

    更新日期:2014-01-01 00:00:00

  • CpG ODN and ISCOMATRIX adjuvant: a synergistic adjuvant combination inducing strong T-Cell IFN-γ responses.

    abstract::For the induction of robust humoral and cellular immune responses, a strong rationale exists to use vaccine-adjuvant combinations possessing both immune modulatory and enhanced delivery capabilities. Herein, we evaluated the combination of 2 different adjuvants, a TLR9 agonist, composed of synthetic oligodeoxynucleoti...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/636847

    authors: McCluskie MJ,Weeratna RD,Evans DM,Makinen S,Drane D,Davis HL

    更新日期:2013-01-01 00:00:00

  • A Bibliometric Analysis of Publications on Oxycodone from 1998 to 2017.

    abstract:Background:Oxycodone is a widely used opioid analgesic, which is involved in cancer pain and non-cancer pain. This study is intended to understand the publication characteristics of oxycodone research field and assess the quality of pertinent articles from 1998 to 2017. Methods:Oxycodone-related publications from 1998...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/9096201

    authors: Lei F,Ye J,Wang J,Xia Z

    更新日期:2019-10-31 00:00:00

  • Customized Scaffold Design Based on Natural Peripheral Nerve Fascicle Characteristics for Biofabrication in Tissue Regeneration.

    abstract:Objective:The use of a biofabrication nerve scaffold, which mimics the nerve microstructure, as an alternative for autologous nerve transplantation is a promising strategy for treating peripheral nerve defects. This study aimed to design a customized biofabrication scaffold model with the characteristics of human perip...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/3845780

    authors: Yao Z,Yan LW,Qiu S,He FL,Gu FB,Liu XL,Qi J,Zhu QT

    更新日期:2019-12-14 00:00:00

  • Modification of Mechanical Properties, Polymerization Temperature, and Handling Time of Polymethylmethacrylate Cement for Enhancing Applicability in Vertebroplasty.

    abstract::Polymethylmethacrylate (PMMA) bone cement is a popular bone void filler for vertebroplasty. However, the use of PMMA has some drawbacks, including the material's excessive stiffness, exothermic polymerization, and short handling time. This study aimed to create an ideal modified bone cement to solve the above-mentione...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/7901562

    authors: Tai CL,Lai PL,Lin WD,Tsai TT,Lee YC,Liu MY,Chen LH

    更新日期:2016-01-01 00:00:00

  • Pharmacodynamic effect of clopidogrel in patients undergoing transcatheter aortic valve implantation.

    abstract::The aim of this study was to analyze periprocedural and mid-term effect of clopidogrel on platelet function using the VerifyNow P2Y12 point-of-care assay in patients undergoing TAVI. Platelet reactivity was measured at the beginning of the procedure after 300 mg clopidogrel bolus administration and during the follow-u...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/386074

    authors: Tousek P,Kocka V,Sulzenko J,Bednar F,Linkova H,Widimsky P

    更新日期:2013-01-01 00:00:00