Oculometric behavior assessed by pupil response is altered in adolescent depression.

abstract：:Hypersensitive pain response is observed in patients with Parkinson's disease (PD). However, the signal pathways leading to hyperalgesia still need to be clarified. Chronic oxidative stress is one of the hallmarks of PD pathophysiology. Since the midbrain periaqueductal gray (PAG) is an important component of the desc...

journal_title：Physiological research

authors： Zhang W,Sun L,Yang X,Wang R,Wang H

更新日期：2020-08-31 00:00:00

abstract：:The effects of inclusion of sesamin / episesamin in Baltic Atlantic salmon (Salmo salar L.) diets based on vegetable oils were studied. The study was designed as a dose response study with two control diets, one diet based on fish oil (FO) and one diet based on a mixture of linseed and sunflower oil (6:4 by vol.) (MO)...

journal_title：Physiological research

authors： Trattner S,Ruyter B,Ostbye TK,Kamal-Eldin A,Moazzami A,Pan J,Gjoen T,Brännäs E,Zlabek V,Pickova J

更新日期：2011-01-01 00:00:00

abstract：:Fibroblast growth factor-21 (FGF-21) has been recently characterized as a new adipokine. The aim of this study was to assess FGF-21 levels in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) and to study the relationship between FGF-21, disease activity and metabolic status. The levels of FGF-21 in seru...

journal_title：Physiological research

authors： Hulejová H,Andrés Cerezo L,Kuklová M,Pecha O,Vondráček T,Pavelka K,Vencovský J,Haluzík M,Senolt L

更新日期：2012-01-01 00:00:00

abstract：:The present study was designed to measure interstitial levels of norepinephrine-regulating lipolysis (NE) in subcutaneous abdominal adipose tissue of anorexia nervosa (AN) patients and control subjects under basal conditions and after the local administration of an inhibitor of NE re-uptake, maprotiline. In vivo micro...

journal_title：Physiological research

authors： Nedvídková J,Dostálová I,Barták V,Papezov H,Pacák K

更新日期：2004-01-01 00:00:00

abstract：:Store-operated calcium entry (SOCE) is one of regulatory mechanisms which regulates Ca2+ cycling in the heart. SOCE alterations in pathological conditions contribute to progression of heart failure and cardiac hypertrophy by multiple signaling pathways such as Cn/NFAT and CaMKII/MEF2. Several components mediating SOCE...

journal_title：Physiological research

authors： Čendula R,Dragún M,Gažová A,Kyselovič J,Hulman M,Máťuš M

更新日期：2019-11-30 00:00:00

abstract：:The aim of the study was to evaluate short-term heart rate variability (HRV) as an index of cardiac autonomic control in rats with lipopolysaccharide (LPS)-induced endotoxemia. Animals were injected intraperitoneally with LPS (100 microg/kg b.w.) and control group with an equivalent volume of saline. ECG recordings we...

journal_title：Physiological research

authors： Zila I,Mokra D,Kopincova J,Kolomaznik M,Javorka M,Calkovska A

更新日期：2015-01-01 00:00:00

abstract：:The aim of the present study was to compare the oscillations of oxygenation in skeletal muscle between early and late phases in prolonged exercise. During prolonged exercise at 60 % of peak oxygen uptake (V(.)o(2)) for 60 min and at rest, oxygenated hemoglobin/myoglobin (Hb/MbO(2)) and total Hb/Mb (THb/Mb) were determ...

journal_title：Physiological research

authors： Yano T,Lian CS,Arimitsu T,Yamanaka R,Afroundeh R,Shirakawa K,Yunoki T

更新日期：2013-01-01 00:00:00

abstract：:The GH4C1 pituitary cell line, an excellent model for a thyroid hormone action study, was used for determination of the relationship between thyroid hormone receptor occupancy and intensity of cell proliferation, prolactin (PRL) production, thyrotropin (TSH) inhibition and 3,5,3,-L-triiodothyronine (T3) receptor down-...

journal_title：Physiological research

authors： Filipcík P,Strbák V,Brtko J

更新日期：1998-01-01 00:00:00

abstract：:Epoxyeicosatrienoic acids (EETs) are also known as epoxyeicosanoids that have renal and cardiovascular actions. These renal and cardiovascular actions can be regulated by soluble epoxide hydrolase (sEH) that degrades and inactivates EETs. Extensive animal hypertension studies have determined that vascular, epithelial ...

journal_title：Physiological research

authors： Imig JD

更新日期：2019-10-25 00:00:00

abstract：:Ferritin and increased iron stores first appeared on the list of cardiovascular risk factors more than 30 years ago and their causal role in the pathogenesis of atherosclerosis has been heavily discussed since the early 1990s. It seems that besides traditional factors such as hyperlipoproteinemia, hypertension, diabet...

journal_title：Physiological research

authors： Kraml P

更新日期：2017-04-05 00:00:00

abstract：:For better understanding of pathophysiological processes leading to increased retention of sodium as a consequence of hyperlipidemia, the properties of renal Na,K-ATPase, a key enzyme involved in maintaining sodium homeostasis in the organism, were studied. Enzyme kinetics of renal Na,K-ATPase were used for characteri...

journal_title：Physiological research

authors： Vrbjar N,Mézešová L,Javorková V,Vlkovičová J,Mitašíková M,Dlugošová K,Okruhlicová L,Tribulová N

更新日期：2011-01-01 00:00:00

abstract：:We studied the psychophysiology of soluble intercellular adhesion molecule-1 (sICAM-1) in 25 apparently healthy middle-aged men who underwent an acute psychosocial stressor three times with one week apart. Measures of the biological stress response were obtained at week one and three. The magnitude of the sICAM-1 stre...

journal_title：Physiological research

authors： von Känel R,Preckel D,Kudielka BM,Fischer JE

更新日期：2007-01-01 00:00:00

abstract：:The paper presents an example of a new type of a structured model containing time delays in parallel branches. This model was selected as optimal to describe mathematically the lymphocyte migration between the venous blood and prescapular lymph in Merino ewes under physiological conditions. The model allowed to identi...

journal_title：Physiological research

authors： Dedík L,Durisová M,Srikusalanukul W,McCullagh P

更新日期：1999-01-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) has an important role in the pathogenesis of retinopathy of prematurity (ROP) and inhibition of VEGF expression in the neovascular phase might prevent destructive neovascularization in ROP. It is suggested that retinoids exert a highly potent antiangiogenic activity by inhibit...

journal_title：Physiological research

authors： Ozkan H,Duman N,Kumral A,Kasap B,Ozer EA,Lebe B,Yaman A,Berk T,Yilmaz O,Ozer E

更新日期：2006-01-01 00:00:00

abstract：:Psychostimulants, including methamphetamine (MA), have neurotoxic effect, especially, if they are targeting CNS during its critical periods of development. The present study was aimed to examine cognitive changes after prenatal and neonatal MA treatment in combination with chronic MA exposure in adulthood of male rats...

journal_title：Physiological research

authors： Hrebíčková I,Ševčíková M,Nohejlová K,Šlamberová R

更新日期：2016-12-22 00:00:00

abstract：:The aim of this study was to determine the effect of chronic crowding on the cardiovascular system of Wistar-Kyoto (WKY) rats. Rats were randomly divided into the control (480 cm(2) per rat) or crowded (200 cm(2) per rat) group for eight weeks. Body weight, blood pressure (BP), heart rate and plasma nitrate/nitrite le...

journal_title：Physiological research

authors： Bernátová I,Púzserová A,Navarová J,Csizmadiová Z,Zeman M

更新日期：2007-01-01 00:00:00

abstract：:It is believed that atherogenesis is a multifactorial process, which could already start in utero. Development of atherosclerosis progresses over decades and leads to the cardiovascular morbidity and mortality in adulthood. At present, we have no exact explanation for all the risk factors acting in the pathogenesis of...

journal_title：Physiological research

authors： Szitányi P,Janda J,Poledne R

更新日期：2003-01-01 00:00:00

abstract：:The aim of the present work was to investigate a new mechanism likely contributing to the toxic action of acetaminophen, especially to explore the possible inhibition of glutathione reductase through an acetaminophen-glutathione conjugate (APAP-SG). APAP-SG conjugate was synthesized by organic synthesis and purified b...

journal_title：Physiological research

authors： Rousar T,Pařík P,Kucera O,Bartos M,Červinková Z

更新日期：2010-01-01 00:00:00

abstract：:Pattern of right ventricular pressure (RVP) fall and its afterload dependence were examined by analyzing ventricular pressure curves and corresponding pressure dP/dt phase planes obtained in both ventricles in the rat heart in situ. Time and value of dP/dt(min), and the time constant tau were measured at baseline and ...

journal_title：Physiological research

authors： Correia-Pinto J,Henriques-Coelho T,Magalhães S,Leite-Moreira AF

更新日期：2004-01-01 00:00:00

abstract：:New knowledge about the neural aspects of cough has revealed a complex network of pathways that initiate cough. The effect of inflammation on cough neural processing occurs at multiple peripheral and central sites within the nervous system. Evidence exists that direct or indirect neuroimmune interaction induces a comp...

journal_title：Physiological research

authors： Kunc P,Fabry J,Lucanska M,Zatko T,Grendar M,Pecova R

更新日期：2020-03-27 00:00:00

abstract：:Continuous normobaric hypoxia (CNH) renders the heart more tolerant to acute ischemia/reperfusion injury. Protein kinase C (PKC) is an important component of the protective signaling pathway, but the contribution of individual PKC isoforms under different hypoxic conditions is poorly understood. The aim of this study ...

journal_title：Physiological research

authors： Holzerová K,Hlaváčková M,Žurmanová J,Borchert G,Neckář J,Kolář F,Novák F,Nováková O

更新日期：2015-01-01 00:00:00

abstract：:The administration of a diet containing 5% of dried oyster mushroom to male Wistar rats fed a cholesterol diet (0.3%) shortly after weaning for 8 weeks reduced cholesterol levels in the serum and liver by 27 and 33%, respectively and increased the fractional turnover rate of 125I-very-low-density lipoproteins (VLDL) b...

journal_title：Physiological research

authors： Bobek P,Ozdín L

更新日期：1994-01-01 00:00:00

abstract：:The oxidative stress plays an important role in the development of cardiovascular diseases (CVD). In CVD progression an aberrant redox regulation was observed. In this regulation levels of reactive oxygen species (ROS) play an important role in cellular signaling, where Nrf2 is the key regulator of redox homeostasis. ...

journal_title：Physiological research

authors： Barančík M,Grešová L,Barteková M,Dovinová I

更新日期：2016-09-19 00:00:00

abstract：:We report that decreased expression of miR-30c in tumor compared to adjacent tissue is sex-dependent in colorectal cancer (CRC) patients. High expression of miR-30c was associated with better survival in the whole cohort. When the cohort was split into male and female subcohorts, decreased miR-30c expression in tumor ...

journal_title：Physiological research

authors： Herichova I,Reis R,Hasakova K,Vician M

更新日期：2020-12-31 00:00:00

abstract：:TGF-beta superfamily members including bone morphogenetic proteins (BMPs) and their receptors (BMPR-1A, -1B and -2) have been shown to be important for reproductive function in both males and females, while information on the role of BMPs in males is limited. Functional studies on select BMPs and BMP receptors have de...

journal_title：Physiological research

authors： Ciller IM,Palanisamy SK,Ciller UA,McFarlane JR

更新日期：2016-11-08 00:00:00

abstract：:The present study was performed to evaluate the role of neuronal nitric oxide synthase (nNOS)-derived nitric oxide (NO) during the developmental phase of hypertension in transgenic rats harboring the mouse Ren-2 renin gene (TGR). The first aim of the present study was to examine nNOS mRNA expression in the renal corte...

journal_title：Physiological research

authors： Cervenka L,Kramer HJ,Malý J,Vanecková I,Bäcker A,Bokemeyer D,Bader M,Ganten D,Mitchell KD

更新日期：2002-01-01 00:00:00

abstract：:The circadian rhythms of many behavioral and physiological functions are regulated by the major circadian pacemaker in the suprachiasmatic nucleus. Long-term opiate addiction and drug withdrawal may affect circadian rhythmicity of various hormones or the sleep/activity pattern of many experimental subjects; however, l...

journal_title：Physiological research

authors： Pačesová D,Novotný J,Bendová Z

更新日期：2016-07-18 00:00:00

abstract：:Parvalbumin (PV) is a calcium-binding protein that is expressed by numerous neuronal subpopulations in the central nervous system. Staining for PV was often used in neuroanatomical studies in the past. Recently, several studies have suggested that PV acts in neurons as a mobile endogenous calcium buffer that affects t...

journal_title：Physiological research

authors： ZACHAROVA G,SOJKA D,PALECEK J

更新日期：2009-01-01 00:00:00

abstract：:Nephrotoxicity of cisplatin (CP) involves renal oxidative stress and inflammation, and sesamin (a major liganin in many plants) has strong antioxidant and antiinflammatory actions. Therefore, we investigated here the possible mitigative action of sesamin on CP nephrotoxicity in rats. Sesamin was given orally (5 mg/kg/...

journal_title：Physiological research

authors： Ali BH,Al Salam S,Al Suleimani Y,Al Za'abi M,Ashique M,Manoj P,Sudhadevi M,Al Tobi M,Nemmar A

更新日期：2020-02-19 00:00:00

abstract：:Graves' disease affects approximately 3 % of women and 0.5 % of men. The first-choice therapy is based on the administration of thyrostatic drugs. However, approximately half of patients relapse within two years of discontinuation. These patients must then decide whether to re-initiate thyrostatics, which may have ser...

journal_title：Physiological research

authors： Vejrazkova D,Vcelak J,Vaclavikova E,Vankova M,Zajickova K,Duskova M,Vrbikova J,Bendlova B

更新日期：2018-11-28 00:00:00