Safety and Efficacy of a New Ultrathin Sirolimus-Eluting Stent with Abluminal Biodegradable Polymer in Real-World Practice.

Abstract:

BACKGROUND AND OBJECTIVES:Recently, Genoss drug-eluting stent (DES)™ stent comprising cobalt-chromium platform with an ultrathin strut thickness, sirolimus, and an abluminal biodegradable polymer was developed. Owing to the lack of substantial evidence for the safety and efficacy of this stent, we report 12-month results of the Genoss DES™ stent. METHODS:We analyzed subjects who were eligible for a 12-month follow-up from the ongoing Genoss DES™ registry, which is a prospective, single-arm, observational, multicenter trial to investigate the clinical outcomes after the successful Genoss DES™ stent implantation among all-comers. The primary endpoint was a device-oriented composite outcome, defined as cardiac death, target vessel-related myocardial infarction, and target lesion revascularization at 12-month follow-up. RESULTS:Among 622 subjects, the mean age of subjects was 66.5±10.4 years, 70.6% were males, 67.5% had hypertension, and 38.3% had diabetes. The implanted stent number, diameter, and length per patient were 1.5±0.8, 3.1±0.4 mm, and 36.0±23.3 mm, respectively. At 12-month clinical follow-up, the primary endpoint occurred only in 4 (0.6%) subjects. CONCLUSIONS:The novel Genoss DES™ stent exhibited excellent safety and efficacy in real-world practice.

journal_name

Korean Circ J

authors

Youn YJ,Yoo SY,Lee JW,Ahn SG,Lee SH,Yoon J,Park JH,Choi WG,Cho S,Lim SW,Jang YS,Kwon KH,Lee NH,Doh JH,Kang WC,Jeon DW,Lee BK,Heo JH,Hong BK,Choi HH

doi

10.4070/kcj.2019.0258

subject

Has Abstract

pub_date

2020-04-01 00:00:00

pages

317-327

issue

4

eissn

1738-5520

issn

1738-5555

pii

50.e34

journal_volume

50

pub_type

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