Identification and Characterization of a Novel Basic Helix-Loop-Helix Transcription Factor of Phospholipid Synthesis Regulation in Aspergillus niger.

abstract：:Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin American caused by the thermodimorphic fungi of the genus Paracoccidioides spp. Notably, a Th1 immune response is required to control PCM. In this context, dendritic cells (DCs) seem to be essential players in capture, processing and presentation of Paracocci...

journal_title：Frontiers in microbiology

authors： Silva LBR,Taira CL,Dias LS,Souza ACO,Nosanchuk JD,Travassos LR,Taborda CP

更新日期：2019-07-31 00:00:00

abstract：:Fibronectin is a multidomain glycoprotein found ubiquitously in human body fluids and extracellular matrices of a variety of cell types from all human tissues and organs, including intestinal epithelial cells. Fibronectin plays a major role in the regulation of cell migration, tissue repair, and cell adhesion. Importa...

journal_title：Frontiers in microbiology

authors： Hymes JP,Klaenhammer TR

更新日期：2016-09-22 00:00:00

abstract：:Genes belonging to the same operon are transcribed as a single mRNA molecule in all prokaryotes. The genes of the same operon are presumed to be involved in similar metabolic and physiological processes. Hence, computational analysis of constituent proteins could provide important clues to the functional relationships...

journal_title：Frontiers in microbiology

authors： Mushtaq K,Sheikh JA,Amir M,Khan N,Singh B,Agrewala JN

更新日期：2015-04-27 00:00:00

abstract：:A microbe is a microscopic organism which may exists in its single-celled form or in a colony of cells. In recent years, accumulating researchers have been engaged in the field of uncovering microbe-disease associations since microbes are found to be closely related to the prevention, diagnosis, and treatment of many ...

journal_title：Frontiers in microbiology

authors： He BS,Peng LH,Li Z

更新日期：2018-11-01 00:00:00

abstract：:Advances in high-throughput sequencing technologies allow a more complete study of microbial plankton community composition and diversity, especially in the rare microbial biosphere. The DNA extraction of plankton is a key step for such studies; however, little is known about its influences on the abundant or rare mic...

journal_title：Frontiers in microbiology

authors： Liu M,Xue Y,Yang J

更新日期：2019-03-11 00:00:00

abstract：:Chandipura Virus (CHPV) a negative-stranded RNA virus belonging to the Rhabdoviridae family, has been previously reported to bring about neuronal apoptosis by stimulating oxidative stress. Our in silico data suggested the involvement of Angiotensin II in intracellular Ca2+ secretion within CHPV infected cells that fur...

journal_title：Frontiers in microbiology

authors： Verma AK,Ghosh S,Basu A

更新日期：2018-07-06 00:00:00

abstract：:The golden orb-weaver spider Nephila clavipes, known for its sexual size dimorphism, is abundant and widespread in the New World. The first annotated genome of orb-weaver spiders, exploring N. clavipes, has recently been reported. The study, focused primarily on the diversity of silk specific genes, shed light into th...

journal_title：Frontiers in microbiology

authors： Debat HJ

更新日期：2017-10-25 00:00:00

abstract：:Consumption of cucumbers (Cucumis sativus var. sativus) has been linked to several foodborne outbreaks involving Salmonella enterica. The purpose of this work was to investigate the efficiency of colonization and internalization of S. enterica into cucumber plants by various routes of contamination. Produce-associated...

journal_title：Frontiers in microbiology

authors： Burris KP,Simmons OD,Webb HM,Deese LM,Moore RG,Jaykus LA,Zheng J,Reed E,Ferreira CM,Brown EW,Bell RL

更新日期：2020-05-29 00:00:00

abstract：:Desulfotomaculum reducens strain MI-1 is a Gram-positive, sulfate-reducing bacterium also capable of reducing Fe(III). Metal reduction in Gram-positive bacteria is poorly understood. Here, we investigated Fe(III) reduction with lactate, a non-fermentable substrate, as the electron donor. Lactate consumption is concomi...

journal_title：Frontiers in microbiology

authors： Dalla Vecchia E,Shao PP,Suvorova E,Chiappe D,Hamelin R,Bernier-Latmani R

更新日期：2014-08-19 00:00:00

abstract：:Coronavirus (CoV) envelope (E) protein is a small structural protein critical for virion morphogenesis and release. The recently characterized E protein ion channel activity (EIC) has also been implicated in modulating viral pathogenesis. In this study, we used infectious bronchitis coronavirus (IBV) as a model to stu...

journal_title：Frontiers in microbiology

authors： Li S,Yuan L,Dai G,Chen RA,Liu DX,Fung TS

更新日期：2020-01-24 00:00:00

abstract：:Clostridium difficile PCR ribotype (RT) 014 is well-established in both human and porcine populations in Australia, raising the possibility that C. difficile infection (CDI) may have a zoonotic or foodborne etiology. Here, whole genome sequencing and high-resolution core genome phylogenetics were performed on a contem...

journal_title：Frontiers in microbiology

authors： Knight DR,Squire MM,Collins DA,Riley TV

更新日期：2017-01-11 00:00:00

abstract：:Low-dose tolerance using heat-killed mycobacteria has been tested as a means of stopping progression toward active tuberculosis (TB) lesions in a human-like murine model using C3HeB/FeJ mice. In the present study, we studied the effect of different treatment schedules with heat-killed non-tuberculous-mycobacteria (NTM...

journal_title：Frontiers in microbiology

authors： Cardona P,Marzo-Escartín E,Tapia G,Díaz J,García V,Varela I,Vilaplana C,Cardona PJ

更新日期：2016-01-05 00:00:00

abstract：:To date, nuclear localization signals (NLSs) that target proteins to nuclei in oomycetes have not been defined, but have been assumed to be the same as in higher eukaryotes. Here, we use the soybean pathogen Phytophthora sojae as a model to investigate these sequences in oomycetes. By establishing a reliable in vivo N...

journal_title：Frontiers in microbiology

authors： Fang Y,Jang HS,Watson GW,Wellappili DP,Tyler BM

更新日期：2017-02-02 00:00:00

abstract：:Glycerol is one of the most important by-products of alcohol fermentation, and depending on its concentration it can contribute to wine flavor intensity and aroma volatility. Here, we evaluated the potential of utilizing the natural genetic variation of non-coding regions in budding yeast to identify allelic variants ...

journal_title：Frontiers in microbiology

authors： Tapia SM,Cuevas M,Abarca V,Delgado V,Rojas V,García V,Brice C,Martínez C,Salinas F,Larrondo LF,Cubillos FA

更新日期：2018-07-03 00:00:00

abstract：:The study evaluated the in vitro antimicrobial and antibiofilm efficacy of an antimicrobial peptide (AMP), lactoferricin (17-30) [Lfcin (17-30)], against biofilm-forming multi-drug-resistant (MDR) strains of enteroaggregative Escherichia coli (EAEC), and subsequently, the in vivo antimicrobial efficacy was assessed in...

journal_title：Frontiers in microbiology

authors： Vergis J,Malik SS,Pathak R,Kumar M,Ramanjaneya S,Kurkure NV,Barbuddhe SB,Rawool DB

更新日期：2020-09-18 00:00:00

abstract：:Listeria monocytogenes (Lm) is a foodborne zoonotic pathogen that causes listeriosis with a mortality rate of 20-30%. Serovar 4b and 1/2b isolates account for most of listeriosis outbreaks, however, no listeriosis vaccine is available for either prophylactic or therapeutic use. Here, we developed a triple-virulence-ge...

journal_title：Frontiers in microbiology

authors： Meng F,Zhu T,Yao H,Ling Z,Feng Y,Li G,Li J,Sun X,Chen J,Meng C,Jiao X,Yin Y

更新日期：2020-12-11 00:00:00

abstract：:The eastern China marginal seas (ECMS) are prominent examples of river-dominated ocean margins, whose most characteristic feature is the existence of isolated mud patches on sandy sediments. Ammonia-oxidizing prokaryotes play a crucial role in the nitrogen cycles of many marine environments, including marginal seas. H...

journal_title：Frontiers in microbiology

authors： Yu S,Yao P,Liu J,Zhao B,Zhang G,Zhao M,Yu Z,Zhang XH

更新日期：2016-02-12 00:00:00

abstract：:The yeast cell is surrounded by a cell wall conferring protection and resistance to environmental conditions that can be harmful. Identify the molecular cues (genes) which shape the biochemical composition and the nanomechanical properties of the cell wall and the links between these two parameters represent a major i...

journal_title：Frontiers in microbiology

authors： Schiavone M,Déjean S,Sieczkowski N,Castex M,Dague E,François JM

更新日期：2017-09-27 00:00:00

abstract：:Symbioses between chemoautotrophic sulfur-oxidizing (thiotrophic) bacteria and protists or animals are among the most diverse and prevalent in the ocean. They are extremely difficult to maintain in aquaria and no thiotrophic symbiosis involving an animal host has ever been successfully cultivated. In contrast, we have...

journal_title：Frontiers in microbiology

authors： Bright M,Espada-Hinojosa S,Lagkouvardos I,Volland JM

更新日期：2014-04-07 00:00:00

abstract：:Loop-mediated isothermal amplification (LAMP) technology has been applied in a wide range of fields such as detection of foodborne bacteria and clinical pathogens due to its simplicity and efficiency. However, existing LAMP primer designing systems require a conserved gene or a short genome region as input, and they c...

journal_title：Frontiers in microbiology

authors： Jia B,Li X,Liu W,Lu C,Lu X,Ma L,Li YY,Wei C

更新日期：2019-12-13 00:00:00

abstract：:The changes of gastric microbiome across stages of neoplastic progression remain poorly understood, especially for intraepithelial neoplasia (IN) which has been recognized as a phenotypic bridge between atrophic/intestinal metaplastic lesions and invasive cancer. The gastric microbiota was investigated in 30 healthy c...

journal_title：Frontiers in microbiology

authors： Wang Z,Gao X,Zeng R,Wu Q,Sun H,Wu W,Zhang X,Sun G,Yan B,Wu L,Ren R,Guo M,Peng L,Yang Y

更新日期：2020-05-29 00:00:00

abstract：:Heterotrophic bacterioplankton communities play an important role in organic matter processing in the oceans worldwide. In order to investigate the significance of distinct phylogenetic bacterial groups it is not only important to assess their quantitative abundance but also their growth dynamics in relation to the en...

journal_title：Frontiers in microbiology

authors： Bakenhus I,Dlugosch L,Billerbeck S,Giebel HA,Milke F,Simon M

更新日期：2017-09-13 00:00:00

abstract：:The gene pair hgcAB is essential for microbial mercury methylation. Our understanding of its abundance and diversity in nature is rapidly evolving. In this study we developed a new broad-range primer set for hgcAB, plus an expanded hgcAB reference library, and used these to characterize Hg-methylating communities from...

journal_title：Frontiers in microbiology

authors： Gionfriddo CM,Wymore AM,Jones DS,Wilpiszeski RL,Lynes MM,Christensen GA,Soren A,Gilmour CC,Podar M,Elias DA

更新日期：2020-10-06 00:00:00

abstract：:Many Gram-negative bacteria use a type VI secretion system (T6SS) for microbial warfare and/or host manipulation. Acinetobacter baumannii is an important nosocomial pathogen and many A. baumannii strains utilize a T6SS to deliver toxic effector proteins to surrounding bacterial cells. These toxic effectors are usually...

journal_title：Frontiers in microbiology

authors： Lewis JM,Deveson Lucas D,Harper M,Boyce JD

更新日期：2019-10-30 00:00:00

abstract：:Putrescine is widely used in industrial production of bioplastics, pharmaceuticals, agrochemicals, and surfactants. Although engineered Corynebacterium glutamicum has been successfully used to produce high levels of putrescine, the overall cellular physiological and metabolic changes caused by overproduction of putres...

journal_title：Frontiers in microbiology

authors： Li Z,Liu JZ

更新日期：2017-10-17 00:00:00

abstract：:Carbapenem resistance among strains of the nosocomial pathogen Klebsiella pneumoniae is increasing worldwide, causing serious clinical infections and higher mortality rates. Polymyxins are some of the few "last resort" options for treatment of carbapenem-resistant Enterobacteriaceae, including K. pneumoniae, however, ...

journal_title：Frontiers in microbiology

authors： Zhou Y,Wang T,Guo Y,Liu S,Wang J,Shen Y,Tang S,Wang Y,Deng X

更新日期：2018-07-17 00:00:00

abstract：:Plant defensins are active against plant and human pathogenic fungi (such as Candida albicans) and baker's yeast. However, they are non-toxic to human cells, providing a possible source for treatment of fungal infections. In this study, we characterized the mode of action of the antifungal plant defensin HsAFP1 from c...

journal_title：Frontiers in microbiology

authors： Aerts AM,Bammens L,Govaert G,Carmona-Gutierrez D,Madeo F,Cammue BP,Thevissen K

更新日期：2011-03-16 00:00:00

abstract：:DNA polymerase is a ubiquitous enzyme that synthesizes complementary DNA strands according to the template DNA in living cells. Multiple enzymes have been identified from each organism, and the shared functions of these enzymes have been investigated. In addition to their fundamental role in maintaining genome integri...

journal_title：Frontiers in microbiology

authors： Ishino S,Ishino Y

更新日期：2014-08-29 00:00:00

abstract：:Alternaria is an important fungus to study due to their different life style from saprophytes to endophytes and a very successful fungal pathogen that causes diseases to a number of economically important crops. Alternaria species have been well-characterized for the production of different host-specific toxins (HSTs)...

journal_title：Frontiers in microbiology

authors： Meena M,Gupta SK,Swapnil P,Zehra A,Dubey MK,Upadhyay RS

更新日期：2017-08-08 00:00:00

abstract：:Simultaneous use of both heterotrophic and autotrophic metabolism ("mixotrophy") is common among protists. Strombidium rassoulzadegani is a planktonic mixotrophic marine ciliate that saves chloroplasts from its algal food and obtains a nutritional subsidy via photosynthesis. Cultures from the northeast, northwest, and...

journal_title：Frontiers in microbiology

authors： McManus GB,Schoener DM,Haberlandt K

更新日期：2012-09-04 00:00:00