Abstract：
:Neurodegenerative diseases need the drugs to be delivered right inside the brain to maximizing the therapeutic effects. This can be achieved by use of novel targeted delivery systems such as nanoemulsions. Nanoemulsions (NE) are nano-sized emulsions that are manufactured for enhancing the delivery of drugs to the targeted site and minimize adverse effects and toxic reactions. Looking into the advanced pharmaceutical applications of NE, the present review gives an insight to the understanding of the application of NE in NDs like AD, PD and Prion's disease. The review also touches upon the pathophysiology of these ND diseases to have a clear understanding of the molecular aspects of the disease. Finally, the review sets a standpoint of nanoemulsion's significance in the treatment therapy of ND besides the drawbacks associated with the current drug therapy in NDs.
journal_name
Life Scijournal_title
Life sciencesauthors
Nirale P,Paul A,Yadav KSdoi
10.1016/j.lfs.2020.117394subject
Has Abstractpub_date
2020-03-15 00:00:00pages
117394eissn
0024-3205issn
1879-0631pii
S0024-3205(20)30141-7journal_volume
245pub_type
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