Abstract:
OBJECTIVE:To compare clinical outcomes and payments between glioma resections with and without functional mapping. METHODS:The Thomas Reuters MarketScan national longitudinal database was used to identify patients undergoing resection of supratentorial primary malignant glioma with or without functional mapping between 2007 and 2016. Patients were stratified into mapped and unmapped (conventional) groups and subsequently propensity-matched based on demographics, clinical comorbidities, and surgical characteristics (i.e., use of stereotactic navigation, microscope, and intratumoral chemotherapy). Outcomes and charges were compared between matched groups using bivariate analyses. RESULTS:A total of 14,037 patients were identified, of whom 796 (6.0%) received functional mapping. Propensity matching (1:1) resulted in 796 mapped patients and 796 propensity-matched controls. Thirty-day postoperative rates of new-onset seizures, cerebral edema, hemorrhage, and neurologic deficits were significantly lower for the functional mapping group (all P < 0.05). Functional mapping was also associated with shorter hospital length of stay (P = 0.0144), lower 30-day rates of emergency department visits (P = 0.0001), and fewer reoperations (P = 0.0068). Total costs of initial admission were not significantly different between groups. CONCLUSIONS:Intraoperative functional mapping during glioma resection was associated with decreased complications, reoperations, emergency department visits, and shorter lengths of stay. Furthermore, total charges of mapped resections were not significantly different from those of conventional resections. These findings support the usefulness of functional mapping for resection of supratentorial primary malignant gliomas.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Pendharkar AV,Rezaii PG,Ho AL,Sussman ES,Li G,Desai AMdoi
10.1016/j.wneu.2020.01.197subject
Has Abstractpub_date
2020-05-01 00:00:00pages
e328-e335eissn
1878-8750issn
1878-8769pii
S1878-8750(20)30215-1journal_volume
137pub_type
杂志文章abstract:PURPOSE:There is a lack of studies highlighting the outcome by different scores or parameters after surgery for recurrent disc herniations of the lumbar spine at the initial herniation site. This study assessed the quality of life after surgical treatment of recurrent herniations with different standardized validated o...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.02.028
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:Meningeal hemangiopericytoma (HPC) is a rare, aggressive central nervous system tumor that tends to invade locally and to metastasize, and has a high rate of recurrence. METHODS:This study presents a retrospective review of patients managed for intracranial HPC at Rome University Hospital. RESULTS:A total o...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2013.11.009
更新日期:2014-03-01 00:00:00
abstract::A 37-year-old man came to our neurosurgical department with a 2-month history of a progressive invalidating balance disorder. Cerebral magnetic resonance imaging found a T2-weighted hypersignal lesion of the right cerebellopontine angle that severely compressed the brainstem, however the position of cranial nerves was...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.06.182
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Cervical radiculopathy and cervicalgia are commonly managed with spinal epidural steroid injections in the outpatient setting. Although cervical epidural injections are routinely performed, there is potential for significant complications if proper technique and safety measures are not followed. Spinal cord ...
journal_title:World neurosurgery
pub_type:
doi:10.1016/j.wneu.2020.08.090
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Intracranial hemorrhage is a common complication of traumatic brain injury (TBI). The purpose of this study is evaluation of the effect of tranexamic acid (TXA) on hemorrhagic mass growth in TBI patients. PATIENTS AND METHODS:In this randomized, double-blind clinical trial, 149 patients with TBI and any kin...
journal_title:World neurosurgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.wneu.2017.10.075
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To integrate 3-dimensional (3D) intraoperative ultrasound (iUS) data in spinal navigation. METHODS:In 11 patients with intradural spinal tumors, 3D-iUS was performed before and after tumor resection. Intraoperative computed tomography (iCT) was used for automatic patient registration for spinal navigation; f...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.07.188
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The aim of this systematic review was to compare the halo and hard collar in the management of adult odontoid fractures. METHODS:Systematic and independent searches on MEDLINE (PubMed) and the Cochrane Database of Systematic Reviews. Inclusion criteria included studies 1) with clinical outcomes, 2) in adult...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2016.10.035
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:We developed a method for fabricating a three-dimensional hollow and elastic aneurysm model useful for surgical simulation and surgical training. In this article, we explain the hollow elastic model prototyping method and report on the effects of applying it to presurgical simulation and surgical training. M...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2013.10.032
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:There is an increasing trend toward skull base (SB) approaches and retractorless surgery to minimize brain manipulation during surgery. We evaluated the radiographic changes over time after surgical resection of anterior cranial fossa meningiomas with and without both SB approaches and/or fixed retractor syst...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.01.069
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Myoclonic dystonia syndrome (MDS) is a rare inherited movement disorder characterized by the coexistence of myoclonic jerks and dystonia. Deep brain stimulation (DBS) is a promising treatment for patients with MDS that targets the globus pallidus internus or ventral intermediate nucleus (Vim) of the thalamus...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.10.177
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Atherosclerotic stenosis of the extracranial internal carotid artery accounts for 15%-20% of ischemic strokes, depending on the population studied. Carotid endarterectomy (CEA) is the most frequently performed operation to prevent stroke. METHODS:Since the 1990s, several randomized controlled trials have be...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2011.05.037
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Herpes simplex encephalitis (HSE) after neurosurgical procedures is extremely uncommon, and the few published case reports mainly described herpes simplex virus type 1 (HSV-1) as being culpable. We present a rare case of HSV-2 encephalitis after craniotomy and describe its pathophysiology and optimal managem...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2015.11.101
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Sufficient visualization of the operating field is crucial for success in surgery and is important especially concerning minimally invasive and deep approaches in spine surgery. METHODS:The spinal microsurgical approach was imitated using an isolated box that was accessed with different devices. Different l...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.06.013
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:This study was undertaken to evaluate de novo aneurysm formation in the long-term follow-up of patients with clipped aneurysms. METHODS:Of 459 patients who underwent clipping of ruptured cerebral aneurysms at our institution between 1997 and 2008, 119 patients were available in good condition and agreed to u...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2013.06.008
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:In children, decompressive craniectomy is commonly performed in cases of increased intracranial pressure that is not medically managed. Currently, it is standard practice to perform cranioplasty after decompressive craniectomy, although optimal timing for the procedure remains controversial. To date, few stu...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.04.085
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:The concept of enhanced recovery after surgery (ERAS) spread to different surgical specialties to minimize surgical stress response and to reduce length of hospital stay (LOS) and cost. Recently, several studies have reported experience with the ERAS program for spine surgery. The aim of this study is to introd...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.05.139
更新日期:2019-09-01 00:00:00
abstract::Acute lymphoblastic lymphoma is a malignant hematologic disease in childhood but rarely initially involves epidural compartment in adults. A 20-year-old male presented with progressive osphyalgia with constipation. Contrasted magnetic resonance imaging showed multiple vertebrae of hypointense T1 signals and an intrasp...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.09.130
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:The aims of this retrospective cohort study were to 1) identify new alignment risk factors for proximal junctional kyphosis (PJK) in adult spinal deformity (ASD) patients with lower thoracic upper instrumented vertebra (UIV) and 2) determine the effect of junctional tethers on PJK and UIV alignment. METHODS:...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.08.242
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:Application of AO spine injury classification system (AOSICS) to identify the timing of operation for different types of traumatic thoracic/thoracolumbar incomplete spinal cord injury (SCI). METHODS:A single-center prospective cohort study was conducted to enroll patients with thoracic/thoracolumbar incomple...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.05.118
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:Postcraniotomy infections have generally been treated by debridement of infected tissues, disposal of the bone flap, and delayed cranioplasty several months later to repair the resulting skull defect. Debridement followed by retention of the bone flap has also been advocated. Here we propose an alternative op...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2011.02.013
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:To examine the strength and tolerance of the fibrin glue sealant in a situation of extended transsphenoidal surgery. The withstand pressure of fibrin glue sealant was measured using a simple sellar reconstruction model. METHODS:A 15-mm diameter hole at the bottom of a 51-cm high cylinder was covered with a ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2010.04.001
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:To date, no randomized trial has directly addressed the question of whether intravenous (IV) tissue plasminogen activator (tPA) improves outcomes in IV tPA-eligible patients who will eventually undergo endovascular therapy (EVT), or whether a direct EVT strategy is equally effective. We performed a systemati...
journal_title:World neurosurgery
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.wneu.2017.08.040
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to reveal inhibitory effect of gamma knife irradiation on angiogenesis of meningiomas using rat corneal angiogenesis assay. METHODS:A total of 72 rats were divided into three preliminary groups. Each group, consisting of 24 rats, was implanted to World Health Organization (WHO) grade...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2013.06.021
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:After subarachnoid hemorrhage (SAH), headache management is often difficult owing to the need to use multiple analgesic drugs. Fentanyl is an opioid we can use after surgery, and it can decrease pain post SAH. The aim of this study was to investigate the effectiveness and safety of fentanyl for management of...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.10.062
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Hydrogen peroxide (H2O2) solution is commonly used to irrigate wounds because of its hemostatic and antiseptic properties. Previous studies suggest that H2O2 can result in toxicity to keratinocytes and fibroblasts, but complications after H2O2 application, including oxygen embolism, which is one of the most ...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2020.03.035
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Ninety-five percent of the Hong Kong population is Chinese, and no previous epidemiological study has focused on spontaneous subarachnoid hemorrhage (SAH) in Hong Kong. These data would have significant public health implications and can guide future resource allocations and service development in Hong Kong....
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2013.07.128
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:The island sign is a novel imaging predictor for early hematoma growth, implying multifocal active bleeding. The prognostic value of the island sign for long-term outcome in patients with intracranial hemorrhage (ICH) remains unrevealed. The aim of this study is to investigate associations between the island...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.08.056
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Neuroglial cysts are rare intracranial lesions that are believed to originate from the sequestration of neural tube lining during embryogenesis. They can present anywhere within the neuraxis; however, their most common location is the frontal lobe. Cerebellopontine angle (CPA) neuroglial cysts are extremely ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.12.203
更新日期:2019-01-17 00:00:00
abstract:BACKGROUND:Meningiomas are the most common primary intracranial tumor, but the lack of prospective randomized trials has led to different guidelines for their treatment. We proposed a classification of meningiomas that considers surgical removal, histology, and cytogenetic profile, based on a literature review of these...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.05.163
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:Spinal neuronavigation improves accuracy of pedicle screw placement but may increase operative time, and its use in oncologic operations remains relatively unstudied. We compared the use of two-dimensional (2D) fluoroscopy and three-dimensional (3D) spinal neuronavigation relative to operative time in instrum...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.06.016
更新日期:2017-09-01 00:00:00