A pulmonary tuberculosis outbreak in a long-term care facility.

Abstract:

:In long-term care facilities (LTCFs), the elderly are apt to be infected because those with latent tuberculosis infections (LTBIs) are at an increased risk for reactivation and post-primary TB disease. We report an outbreak of TB in staff and residents in a LTCF. An outbreak investigation was conducted after two TB cases were reported from the LTCF. A tuberculin skin test (TST), bacteriological examination and chest radiograph were administered to all facility staff and residents. An outbreak is defined as at least two epidemiologically linked cases that have identical Mycobacterium tuberculosis genotype isolates. This outbreak infected eight residents and one staff member, who were confirmed to have TB in a LTCF between September 2011 and October 2012. Based on the Becker method, the latent and infectious periods were estimated at 223·6 and 55·9 days. Two initial TST-negative resident contacts were diagnosed as TB cases through comprehensive TB screening. Observing elderly people who have a negative TST after TB screening appears to be necessary, given the long latent period for controlling a TB outbreak in a LTCF. It is important to consider providing LTBI treatment for elderly contacts.

journal_name

Epidemiol Infect

authors

Lai CC,Hsieh YC,Yeh YP,Jou RW,Wang JT,Pan SL,Chen HH

doi

10.1017/S0950268815002265

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

1455-62

issue

7

eissn

0950-2688

issn

1469-4409

pii

S0950268815002265

journal_volume

144

pub_type

杂志文章
  • An outbreak of Escherichia coli O157 associated with a children's paddling pool.

    abstract::In May 1992, a small, circumscribed community outbreak of infection due to verotoxin-producing Escherichia coli O157 phage type 49 occurred in a semi-rural area of south-east Scotland. On the basis of stool cultures, six cases were identified, one of whom was asymptomatic. One child developed the haemolytic uraemic sy...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800051141

    authors: Brewster DH,Brown MI,Robertson D,Houghton GL,Bimson J,Sharp JC

    更新日期:1994-06-01 00:00:00

  • Characteristics of within-household varicella transmission events associated with school outbreaks in Shanghai, China, 2009-2018.

    abstract::Transmission of varicella occurs frequently in schools and households. We investigated the characteristics of varicella cases derived from within-household transmission and the modes of varicella transmission between school and household settings in Shanghai, China, from 2009 to 2018. Within-household transmission occ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820000448

    authors: Chen YF,Zhou Q,Liu JY,Gong RJ,Mao SQ,Ye ZJ,Wu QS

    更新日期:2020-02-14 00:00:00

  • Species identification, antibiotic sensitivity and slime production of coagulase-negative staphylococci isolated from clinical specimens.

    abstract::Two hundred and seventy-five consecutive clinical isolates of coagulase-negative staphylococci, including strains associated with disease, contaminants and skin colonizers, were speciated, tested for slime production and for their sensitivity to a range of antibiotics. Staphylococcus epidermidis was the most commonly ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800029265

    authors: Deighton MA,Franklin JC,Spicer WJ,Balkau B

    更新日期:1988-08-01 00:00:00

  • Epidemiological investigations on the potential transmissibility of a rare disease: the case of atypical scrapie in Great Britain.

    abstract::Multiple cases of atypical scrapie in the same holding and co-existence with classical scrapie have been reported in Great Britain. A two-stage simulation tool was developed by combining a sampling algorithm and a hierarchical Bayesian model to simulate the number of positive cases of atypical scrapie from: (i) random...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816000303

    authors: Ortiz-Peláez A,Arnold ME,Vidal-Diez A

    更新日期:2016-07-01 00:00:00

  • Time-course of antibody responses against Coxiella burnetii following acute Q fever.

    abstract::Large outbreaks of Q fever in The Netherlands have provided a unique opportunity for studying longitudinal serum antibody responses in patients. Results are presented of a cohort of 344 patients with acute symptoms of Q fever with three or more serum samples per patient. In all these serum samples IgM and IgG against ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268812000404

    authors: Teunis PF,Schimmer B,Notermans DW,Leenders AC,Wever PC,Kretzschmar ME,Schneeberger PM

    更新日期:2013-01-01 00:00:00

  • The source of Yersinia spp. in pasteurized milk: an investigation at a dairy.

    abstract::Pasteurized bottled milk supplied by a single dairy was frequently found to be contaminated with Yersinia spp. Investigations were carried out at the dairy in an effort to pinpoint the source of these organisms. Viable counts obtained from milk bottle rinses indicated that bottle washing was often unsatisfactory, and ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800047373

    authors: Greenwood MH,Hooper WL,Rodhouse JC

    更新日期:1990-06-01 00:00:00

  • Epidemiology of respiratory syncytial virus in children in Cyprus during three consecutive winter seasons (2010-2013): age distribution, seasonality and association between prevalent genotypes and disease severity.

    abstract::This study reports the epidemiology of respiratory syncytial virus (RSV) in hospitalized children in Cyprus over three successive seasons (2010-2013) and the association between prevalent genotypes and disease severity. RSV infections had a circulation pattern from December to March. Most RSV-positive children (83%) w...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814000028

    authors: Panayiotou C,Richter J,Koliou M,Kalogirou N,Georgiou E,Christodoulou C

    更新日期:2014-11-01 00:00:00

  • Q fever infection in dairy cattle herds: increased risk with high wind speed and low precipitation.

    abstract::Ruminants are considered the main reservoir for transmission of Coxiella burnetii (Cb) to humans. The implementation of effective control measures against Cb in ruminants requires knowledge about potential risk factors. The objectives of this study were (i) to describe the spatial distribution of Q fever-infected dair...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814003926

    authors: Nusinovici S,Frössling J,Widgren S,Beaudeau F,Lindberg A

    更新日期:2015-11-01 00:00:00

  • Time to Rt < 1 for COVID-19 public health lockdown measures.

    abstract::The epidemiological target of lockdowns is to drive down the effective reproduction number (Rt) to less than 1. A key unknown is the duration that lockdowns need to be in place to achieve this and which lockdown measures are effective. Daily number of laboratory confirmed community coronavirus 2019 cases were extracte...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820002964

    authors: Yung CF,Saffari E,Liew C

    更新日期:2020-12-09 00:00:00

  • Community studies on hepatitis B in Rajahmundry town of Andhra Pradesh, India, 1997-8: unnecessary therapeutic injections are a major risk factor.

    abstract::In Rajahmundry town in India, 234 community cases of jaundice were interviewed for risk factors of viral hepatitis B and tested for markers of hepatitis A-E. About 41% and 1.7% of them were positive for anti-HBc and anti-HCV respectively. Of 83 cases who were tested within 3 months of onset of jaundice, 5 (6%), 11 (13...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899003854

    authors: Singh J,Bhatia R,Patnaik SK,Khare S,Bora D,Jain DC,Sokhey J

    更新日期:2000-10-01 00:00:00

  • In99, an In100-related integron, its occurrence and prevalence in clinical Pseudomonas aeruginosa strains from a central region of Portugal.

    abstract::In99, a possible ancestor of In100, is a class 1 integron associated with carbenicillinase (blaPSE) and aminoglycoside resistance genes [aac(6')-Ib and aadA2]. In99 was present in 8 of 81 clinical isolates of Pseudomonas aeruginosa from unrelated patients collected in different years. The strains fell into two clonal ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026880600700X

    authors: Caetano T,Ferreira S,Mondego AP,Correia A,Mendo S

    更新日期:2007-04-01 00:00:00

  • Full-genome sequence analysis of an uncommon norovirus genotype, GII.21, from South Korea.

    abstract::Noroviruses (NoVs) are major causal agents of acute gastroenteritis in humans. NoV GII.4 is the predominant genotype globally. However, uncommon and minor types of NoVs are consistently detected and some have been shown to dominate over GII.4. Therefore, the prevalence of dominant and uncommon NoVs makes the identific...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817001273

    authors: Lee JW,Lee SG,Cho HG,Park YJ,Yun JW,Park CJ,Paik SY

    更新日期:2017-08-01 00:00:00

  • Evaluation of the limiting antigen avidity EIA (LAg) in people who inject drugs in Greece.

    abstract::This analysis assessed the utility of the limiting antigen avidity assay (LAg). Samples of people who inject drugs (PWID) in Greece with documented duration of HIV-1 infection were tested by LAg. A LAg-normalized optical density (ODn) ⩽1·5 corresponds to a recency window period of 130 days. The proportion true recent ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816002417

    authors: Nikolopoulos GK,Katsoulidou A,Kantzanou M,Rokka C,Tsiara C,Sypsa V,Paraskevis D,Psichogiou M,Friedman S,Hatzakis A

    更新日期:2017-01-01 00:00:00

  • Non-specific alert system for dengue epidemic outbreaks in areas of endemic malaria. A hospital-based evaluation in Cayenne (French Guiana).

    abstract::The emergence of dengue haemorrhagic fever is a public health problem in Latin America and the Caribbean. This study, carried out in French Guiana where malaria is endemic, evaluated the value and the limitations of a non-specific alert system including all patients admitted to the emergency department of Cayenne Hosp...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268802007641

    authors: Carme B,Sobesky M,Biard MH,Cotellon P,Aznar C,Fontanella JM

    更新日期:2003-02-01 00:00:00

  • Lack of response of INT-407 cells to the presence of non-culturable Campylobacter jejuni.

    abstract::Many contradictory articles on the infectivity of non-culturable Campylobacter jejuni can be found. We studied the effect of non-culturable C. jejuni in an in vitro assay. To prevent the potential effect of a few culturable bacteria in the non-culturable suspension, INT-407 cells, which mimic the outer cell layer in t...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807000040

    authors: Verhoeff-Bakkenes L,Hazeleger WC,Zwietering MH,De Jonge R

    更新日期:2008-10-01 00:00:00

  • Putative household outbreaks of campylobacteriosis typically comprise single MLST genotypes.

    abstract::During a 15-month period in Scotland a small but important number of human Campylobacter cases (3·2%) arose from 91 putative household outbreaks. Of the 26 outbreaks with known strain composition, 89% were composed of the same MLST which supports the potential use of MLST in public health epidemiology. The number of c...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810001457

    authors: Rotariu O,Smith-Palmer A,Cowden J,Bessell PR,Innocent GT,Reid SW,Matthews L,Dallas J,Ogden ID,Forbes KJ,Strachan NJ

    更新日期:2010-12-01 00:00:00

  • Multi-country outbreak of Salmonella enteritidis infection linked to the international ice hockey tournament.

    abstract::In April 2015, Finnish public health authorities alerted European Union member states of a possible multi-country Salmonella enteritidis outbreak linked to an international youth ice-hockey tournament in Latvia. The European Centre for Disease Prevention and Control (ECDC), Finnish and Latvian authorities initiated an...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817001212

    authors: Pärn T,Dahl V,Lienemann T,Perevosčikovs J,De Jong B

    更新日期:2017-08-01 00:00:00

  • Age-specific vaccine effectiveness of seasonal 2010/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom.

    abstract::An analysis was undertaken to measure age-specific vaccine effectiveness (VE) of 2010/11 trivalent seasonal influenza vaccine (TIV) and monovalent 2009 pandemic influenza vaccine (PIV) administered in 2009/2010. The test-negative case-control study design was employed based on patients consulting primary care. Overall...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268812001148

    authors: Pebody RG,Andrews N,Fleming DM,McMenamin J,Cottrell S,Smyth B,Durnall H,Robertson C,Carman W,Ellis J,Sebastian-Pillai P,Zambon M,Kearns C,Moore C,Thomas DR,Watson JM

    更新日期:2013-03-01 00:00:00

  • Shelter crowding and increased incidence of acute respiratory infection in evacuees following the Great Eastern Japan Earthquake and tsunami.

    abstract::Although outbreaks of acute respiratory infection (ARI) at shelters are hypothesized to be associated with shelter crowding, no studies have examined this relationship. We conducted a retrospective study by reviewing medical records of evacuees presenting to one of the 37 clinics at the shelters in Ishinomaki city, Ja...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815001715

    authors: Kawano T,Tsugawa Y,Nishiyama K,Morita H,Yamamura O,Hasegawa K

    更新日期:2016-03-01 00:00:00

  • A recipe for disaster: outbreaks of campylobacteriosis associated with poultry liver pâté in England and Wales.

    abstract::Despite the frequency of Campylobacter as the principal cause of bacterial gastroenteritis in the UK, outbreaks attributed to this pathogen are rare. One hundred and fourteen general foodborne outbreaks of campylobacteriosis were reported to the Health Protection Agency from 1992 to 2009 with most occurring in food se...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810001974

    authors: Little CL,Gormley FJ,Rawal N,Richardson JF

    更新日期:2010-12-01 00:00:00

  • Detection of HPAI H5N1 viruses in ducks sampled from live bird markets in Vietnam.

    abstract::In Vietnam, highly pathogenic avian influenza (HPAI) H5N1 infections in poultry often occur without concomitant clinical signs and outbreaks are not consistently reported. Live bird markets represent a convenient site for surveillance that does not rely on farmers' notifications. Two H5N1 surveys were conducted at liv...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268812001112

    authors: Phan MQ,Henry W,Bui CB,DO DH,Hoang NV,Thu NT,Nguyen TT,LE TD,Diep TQ,Inui K,Weaver J,Carrique-Mas J

    更新日期:2013-03-01 00:00:00

  • Viral and bacterial co-infection in hospitalised children with refractory Mycoplasma pneumoniae pneumonia.

    abstract::To investigate the impact of viral and bacterial co-infection in hospitalised children with Mycoplasma pneumoniae pneumonia (RMPP). Retrospective analysis of 396 children with RMPP in our hospital admitted between 1 January 2011 and 31 December 2016 was performed. Nasal aspirate samples were collected for pathogen det...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818000778

    authors: Zhang X,Chen Z,Gu W,Ji W,Wang Y,Hao C,He Y,Huang L,Wang M,Shao X,Yan Y

    更新日期:2018-08-01 00:00:00

  • Concomitant leptospirosis-hantavirus co-infection in acute patients hospitalized in Sri Lanka: implications for a potentially worldwide underestimated problem.

    abstract::Two global (re-)emerging zoonoses, leptospirosis and hantavirus infections, are clinically indistinguishable. Thirty-one patients, hospitalized in Sri Lanka for acute severe leptospirosis, were after exclusion of other potentially involved pathogens, prospectively screened with IgM ELISA for both pathogens. Of these, ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814003707

    authors: Sunil-Chandra NP,Clement J,Maes P,DE Silva HJ,VAN Esbroeck M,VAN Ranst M

    更新日期:2015-07-01 00:00:00

  • British Escherichia coli O157 in Cattle Study (BECS): to determine the prevalence of E. coli O157 in herds with cattle destined for the food chain.

    abstract::Escherichia coli O157 are zoonotic bacteria for which cattle are an important reservoir. Prevalence estimates for E. coli O157 in British cattle for human consumption are over 10 years old. A new baseline is needed to inform current human health risk. The British E. coli O157 in Cattle Study (BECS) ran between Septemb...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817002151

    authors: Henry MK,Tongue SC,Evans J,Webster C,McKENDRICK IJ,Morgan M,Willett A,Reeves A,Humphry RW,Gally DL,Gunn GJ,Chase-Topping ME

    更新日期:2017-11-01 00:00:00

  • Improved methods of detection of meningococcal DNA from oropharyngeal swabs from cases and contacts of meningococcal disease.

    abstract::In the UK the increasing use of pre-admission parenteral antibiotic therapy in meningococcal disease has lessened the value of routine cultures as a tool to confirm diagnosis, and laboratory confirmation of invasive meningococcal infection is achieved increasingly by non-culture, nucleic acid amplification methods. Th...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899004367

    authors: Sadler F,Borrow R,Dawson MM,Kaczmarski EB,Cartwright K,Fox AJ

    更新日期:2000-10-01 00:00:00

  • An outbreak of Trichinella spiralis infection in southern Lebanon.

    abstract::An outbreak of trichinosis occurred during January 1995 in a south Lebanese village with a population of 800-1000 persons. The estimated number of persons treated for a Trichinella-like illness was 200. Sixty-three persons sought medical attention at a local infirmary: 44 of them were diagnosed as having trichinosis o...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268897007875

    authors: Haim M,Efrat M,Wilson M,Schantz PM,Cohen D,Shemer J

    更新日期:1997-12-01 00:00:00

  • A community outbreak of haemolytic-uraemic syndrome in children occurring in a large area of northern Italy over a period of several months.

    abstract::From March to October 1993, 15 cases of haemolytic-uraemic syndrome (HUS) in children were detected in a large area of northern Italy, where only 8 cases had occurred in the previous 5 years. Analysis of stool and serum specimens obtained from 14 cases showed evidence of Verotoxin-producing Escherichia coli (VTEC) inf...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800051645

    authors: Tozzi AE,Niccolini A,Caprioli A,Luzzi I,Montini G,Zacchello G,Gianviti A,Principato F,Rizzoni G

    更新日期:1994-10-01 00:00:00

  • Association between Toxoplasma gondii exposure and paediatrics haematological malignancies: a case-control study.

    abstract::The possible association between Toxoplasma gondii infection and paediatric haematological malignancies in a group of patients and control subjects was evaluated in the present study. We performed an age-, gender- and residence frequency-matched case-control study of 101 blood cancer patients under 18 years of age, al...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818002194

    authors: Kalantari N,Rezanejad J,Tamadoni A,Ghaffari S,Alipour J,Bayani M

    更新日期:2018-11-01 00:00:00

  • Comparison of routine field epidemiology and whole genome sequencing to identify tuberculosis transmission in a remote setting.

    abstract::Yukon Territory (YT) is a remote region in northern Canada with ongoing spread of tuberculosis (TB). To explore the utility of whole genome sequencing (WGS) for TB surveillance and monitoring in a setting with detailed contact tracing and interview data, we used a mixed-methods approach. Our analysis included all cult...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820000072

    authors: Guthrie JL,Strudwick L,Roberts B,Allen M,McFadzen J,Roth D,Jorgensen D,Rodrigues M,Tang P,Hanley B,Johnston J,Cook VJ,Gardy JL

    更新日期:2020-02-04 00:00:00

  • Time-series analysis of hepatitis A, B, C and E infections in a large Chinese city: application to prediction analysis.

    abstract::Viral hepatitis is recognized as one of the most frequently reported diseases, and especially in China, acute and chronic liver disease due to viral hepatitis has been a major public health problem. The present study aimed to analyse and predict surveillance data of infections of hepatitis A, B, C and E in Wuhan, Chin...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881200146X

    authors: Sumi A,Luo T,Zhou D,Yu B,Kong D,Kobayashi N

    更新日期:2013-05-01 00:00:00