Abstract:
:To improve the deconstruction of biomass, the most abundant terrestrial source of carbon polymers, en route to renewable fuels, chemicals, and materials more knowledge is needed into the mechanistic interplay between thermochemical pretreatment and enzymatic hydrolysis. In this review we highlight recent progress in advanced imaging techniques that have been used to elucidate the effects of thermochemical pretreatment on plant cell walls across a range of spatial scales and the relationship between the substrate structure and the function of various glycoside hydrolase components. The details of substrate and enzyme interactions are not yet fully understood and the challenges of characterizing plant cell wall architecture, how it dictates recalcitrance, and how it relates to enzyme-substrate interactions is the focus for many research groups in the field. Better understanding of how to match pretreatments with improved enzyme mixtures will lead to lower costs for industrial biorefining.
journal_name
Curr Opin Chem Bioljournal_title
Current opinion in chemical biologyauthors
Donohoe BS,Resch MGdoi
10.1016/j.cbpa.2015.08.014subject
Has Abstractpub_date
2015-12-01 00:00:00pages
100-7eissn
1367-5931issn
1879-0402pii
S1367-5931(15)00102-7journal_volume
29pub_type
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