Minimally invasive surgery for abdominal and thoracic neuroblastic tumors: A systematic review by the APSA Cancer committee.

Abstract:

BACKGROUND:Minimally invasive surgery has broad applicability to pediatric diseases, including pediatric cancer resection. Neuroblastic tumors of childhood are highly variable in presentation, and so careful selection of appropriate candidates for minimally invasive resection is paramount to achieving safe and durable surgical and oncological outcomes. METHODS:The American Pediatric Surgical Association Cancer Committee developed questions seeking to better define the role of minimally invasive surgery for neuroblastic tumors. A search using PubMed, Medline, Embase, Web of Science, ProQuest Dissertations, and Clinical Trials was performed for articles published from 1998 to 2018 in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines. RESULTS:The evidence identified is all retrospective in nature. Minimally invasive surgical resection of neuroblastic tumors is safe for carefully selected smaller (4-6 cm) image defined risk factor (IDRF)-negative abdominal tumors when oncologic principles are followed. Size is a less-well defined criterion for thoracic neuroblastic tumors. Open approaches for both abdominal and thoracic tumors may be preferable in the presence of IDRF's. CONCLUSION:Small tumors without IDRF's are reasonable candidates for minimally invasive resection. Surgical oncologic guidelines should be closely followed. The quality of data supporting this systematic review is poor and highlights the need for refinement in the study of such surgical techniques to improve knowledge and outcomes for patients with neuroblastic tumors. TYPE OF STUDY:Systematic Review. LEVEL OF EVIDENCE:Level III and Level IV.

journal_name

J Pediatr Surg

authors

Gurria JP,Malek MM,Heaton TE,Gehred A,Lautz TB,Rhee DS,Tracy ET,Grant CN,Baertshiger RM,Bruny J,Christison-Lagay ER,Rodeberg DA,Ehrlich PF,Dasgupta R,Aldrink JH

doi

10.1016/j.jpedsurg.2020.02.019

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

2260-2272

issue

11

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(20)30120-2

journal_volume

55

pub_type

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