Abstract:
BACKGROUND:We are developing an intradural approach to spinal cord stimulation, where the thin electrode array is affixed stably to the underside of the thoracic spinal dura mater without leakage of cerebrospinal fluid. As part of the design and testing process, we sought to evaluate the potential risk of inadvertent contact of the array with the pial surface of the spinal cord during variations in spinal loading. METHODS:As part of the risk assessment process, a 2-part study was undertaken. First, a retrospective review of the imaging studies of 25 patients was done in the supine, 45- and 90-degree positions to measure the positional shift between the T9 and T10 vertebral bodies as a function of spinal angulation. Second, similar measurements were made on a cadaveric model, with and without a prototype intradural stimulator implanted at the T9-T10 position and with and without 13.8 kg (30 lb) of axial spinal loading at the 90-degree orientation. RESULTS:In all cases, the measured relative displacement of the dura mater towards the spinal cord in both the imaging and the cadaveric arms of the study was less than 1 mm. CONCLUSIONS:The implantation method for the thin intradural array of the prototype device will ensure that the anatomic separation between it and the pial surface of the spinal cord will be the same as that of the dura mater. Therefore the risk of inadvertent contact will be no greater than that due to the mass effects of standard epidural stimulator implants.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Seaman SC,Zanaty M,Holland MT,Gillies GT,Howard MA 3rd,Yamaguchi Sdoi
10.1016/j.wneu.2020.02.172subject
Has Abstractpub_date
2020-06-01 00:00:00pages
e557-e563eissn
1878-8750issn
1878-8769pii
S1878-8750(20)30458-7journal_volume
138pub_type
杂志文章abstract:BACKGROUND:A spontaneous persistent primitive trigeminal artery-cavernous sinus fistula (PCF) is extremely rare. Until recently, endovascular treatment for PCF involving transarterial and/or transvenous coil embolization of the cavernous sinus (with/without the persistent trigeminal artery) was commonly performed. Howe...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
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更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:The primary training in any surgical practice starts with tissue handling and effective hemostasis. Neurosurgical procedures start with an incision in the scalp and require summative use of mechanical hemostats and bipolar coagulation to achieve hemostasis. Though Raney clips are the most popular and effectiv...
journal_title:World neurosurgery
pub_type: 杂志文章
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abstract:BACKGROUND:The foramen of Luschka is a natural aperture between the fourth ventricle and the subarachnoid space at the cerebellopontine angle. Membranous closure of this foramen is referred to as primary obstruction. Available information about this variant and its role in the development of the cysts of the posterior ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.01.037
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journal_title:World neurosurgery
pub_type: 杂志文章,评审
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journal_title:World neurosurgery
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journal_title:World neurosurgery
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abstract:BACKGROUND:Quantitative magnetic resonance angiography (qMRA) using noninvasive optimal vessel analysis (NOVA) is a novel noninvasive imaging technique that is being increasingly used to measure blood flow in extracranial and intracranial arteries. By providing important quantitative flow data, NOVA qMRA can facilitate...
journal_title:World neurosurgery
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更新日期:2020-03-01 00:00:00
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journal_title:World neurosurgery
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journal_title:World neurosurgery
pub_type: 杂志文章
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更新日期:2021-01-01 00:00:00
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journal_title:World neurosurgery
pub_type: 历史文章,杂志文章,评审
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更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To report a series of four patients with uterine sarcoma, including one with müllerian adenosarcoma (MA) and three with low-grade endometrial stromal sarcoma (LGESS), who developed intracranial meningiomas while receiving the progesterone agonist megestrol acetate. METHODS:The hospital records, imaging studi...
journal_title:World neurosurgery
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更新日期:2011-11-01 00:00:00
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journal_title:World neurosurgery
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更新日期:2020-02-01 00:00:00
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journal_title:World neurosurgery
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更新日期:2020-06-01 00:00:00
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journal_title:World neurosurgery
pub_type: 杂志文章,多中心研究
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更新日期:2017-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-11-01 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.1016/j.wneu.2016.09.056
更新日期:2017-01-01 00:00:00
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更新日期:2020-07-01 00:00:00
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doi:10.1016/j.wneu.2010.07.042
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journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.04.019
更新日期:2016-07-01 00:00:00
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journal_title:World neurosurgery
pub_type: 杂志文章,评审
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更新日期:2017-05-01 00:00:00
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journal_title:World neurosurgery
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更新日期:2019-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.wneu.2018.05.235
更新日期:2018-09-01 00:00:00
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journal_title:World neurosurgery
pub_type: 杂志文章
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更新日期:2019-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.wneu.2020.11.060
更新日期:2020-11-18 00:00:00
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journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.05.245
更新日期:2019-09-01 00:00:00
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journal_title:World neurosurgery
pub_type: 杂志文章
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更新日期:2016-06-01 00:00:00
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journal_title:World neurosurgery
pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00