FAB classification of chronic myelomonocytic leukemia: heterogeneity revealed on the basis of bone marrow findings.

Abstract:

:We report on 12 patients who fulfilled the FAB diagnosis criteria of chronic myelomonocytic leukemia (CMML). Some clinical findings (splenomegaly) as well as biological parameters (WBC count, cellularity of bone marrow sections, presence of dyserythropoiesis in bone marrow smears) were subjected to particular analysis. This allowed the assignment of each patient onto one of three separate hematological syndromes: (1) RA or RAEB with monocytosis, (2) myelomonocytic dysplasia (a novel syndrome) and (3) true CMML. Such separation may have distinct prognostic significance and may, therefore, predict life expectancy.

journal_name

Neoplasma

journal_title

Neoplasma

authors

Yavòrkovsky LL,Solovei DY,Ryauzova LY,Schvidel LM,Zile MA,Sused SG,Teilane IY

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

565-9

issue

5

eissn

0028-2685

issn

1338-4317

journal_volume

35

pub_type

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