Role of neurotrophic factors in enhancing linear axonal growth of ganglionic sensory neurons in vitro.

abstract：:Acupuncture has been shown to ameliorate cognitive impairment of Alzheimer's disease. Acupoints and stimulation frequency influence the therapeutic effect of electroacupuncture. Rat models of Alzheimer's disease were established by injecting amyloid beta 1-42 (Aβ1-42) into the bilateral lateral ventricles. Electroacup...

journal_title：Neural regeneration research

authors： Yu CC,Wang Y,Shen F,Kong LH,Wang YW,Zhou H,Tang L

更新日期：2018-10-01 00:00:00

abstract：:Our previous studies have histomorphologically confirmed that nanofibrous poly(3-hydroxybutyrate-co-3-hydroxyvalerate) conduit can be used to repair 30-mm-long sciatic nerve defects. However, the repair effects on rat behaviors remain poorly understood. In this study, we used nanofibrous poly(3-hydroxybutyrate-co-3-hy...

journal_title：Neural regeneration research

authors： Biazar E,Keshel SH,Pouya M

更新日期：2013-09-25 00:00:00

abstract：:The present study analyzed the anatomical association between intracranial subarachnoid space and the cervical lymphatic system. X-ray contrast medium and Microfil(®) (Microfil compounds fill and opacify microvascular and other spaces of non-surviving animals and post-mortem tissue under physiological injection pressu...

journal_title：Neural regeneration research

authors： Liu H,Ni Z,Chen Y,Wang D,Qi Y,Zhang Q,Wang S

更新日期：2012-04-05 00:00:00

abstract：:Both matrix biochemistry and neurotrophic factors are known to modulate neurite outgrowth and pathfinding; however, the interplay between these two factors is less studied. While previous work has shown that the biochemical identity of the matrix can alter the outgrowth of neurites in response to neurotrophins, the im...

journal_title：Neural regeneration research

authors： Madl CM,Heilshorn SC

更新日期：2015-04-01 00:00:00

abstract：:Decreased expression of brain-derived neurotrophic factor (BDNF) plays an important role in the pathogenesis of Alzheimer's disease, and a typical pathological change in Alzheimer's disease is neurofibrillary tangles caused by hyperphosphorylation of tau. An in vivo model of Alzheimer's disease was developed by inject...

journal_title：Neural regeneration research

authors： Xu AH,Yang Y,Sun YX,Zhang CD

更新日期：2018-12-01 00:00:00

abstract：:The motor relearning program can significantly improve various functional disturbance induced by ischemic cerebrovascular diseases. However, its mechanism of action remains poorly understood. In injured brain tissues, glial fibrillary acidic protein and neurofilament protein changes can reflect the condition of injure...

journal_title：Neural regeneration research

authors： Yin Y,Gu Z,Pan L,Gan L,Qin D,Yang B,Guo J,Hu X,Wang T,Feng Z

更新日期：2013-06-05 00:00:00

abstract：:Damage to peripheral nerve tissue may cause loss of function in both the nerve and the targeted muscles it innervates. This study compared the repair capability of engineered nerve conduit (ENC), engineered fibroblast conduit (EFC), and autograft in a 10-mm tibial nerve gap. ENCs were fabricated utilizing primary fibr...

journal_title：Neural regeneration research

authors： Adams AM,VanDusen KW,Kostrominova TY,Mertens JP,Larkin LM

更新日期：2017-09-01 00:00:00

abstract：:The sciatic functional index (SFI) is a popular parameter for peripheral nerve evaluation that relies on footprints obtained with ink and paper. Drawbacks include smearing artefacts and a lack of dynamic information during measurement. Modern applications use digitized systems that can deliver results with less analyt...

journal_title：Neural regeneration research

authors： Fricker L,Penna V,Lampert F,Stark GB,Witzel C,Koulaxouzidis G

更新日期：2016-05-01 00:00:00

abstract：:Although Parkinson's disease is the most common neurodegenerative movement disorder, the mechanisms of pathogenesis remain poorly understood. Recent findings have shown that deregulation of the autophagy-lysosome pathway is involved in the pathogenesis of Parkinson's disease. This review summarizes the most recent fin...

journal_title：Neural regeneration research

authors： Zhang L,Dong Y,Xu X,Xu Z

更新日期：2012-01-15 00:00:00

abstract：:The influence of duration of immobilization and postoperative sensory re-education on the final outcome after reconstruction of digital nerves with direct suture or muscle-in-vein conduits was investigated. The final sensory outcome of 35 patients with 41 digital nerve injuries, who either underwent a direct suture (D...

journal_title：Neural regeneration research

authors： Manoli T,Schiefer JL,Schulz L,Fuchsberger T,Schaller HE

更新日期：2016-02-01 00:00:00

abstract：:Acupuncture can induce changes in the brain. However, the majority of studies to date have focused on a single acupoint at a time. In the present study, we observed activity changes in the brains of healthy volunteers before and after acupuncture at Taichong (LR3) and Taixi (KI3) using resting-state functional magneti...

journal_title：Neural regeneration research

authors： Zhang SQ,Wang YJ,Zhang JP,Chen JQ,Wu CX,Li ZP,Chen JR,Ouyang HL,Huang Y,Tang CZ

更新日期：2015-02-01 00:00:00

abstract：:Previous studies demonstrate an accumulation of transferrin and transferrin receptor 1 (TfR1) in regenerating peripheral nerves. However, the expression and function of transferrin and TfR1 in the denervated skeletal muscle remain poorly understood. In this study, a mouse model of denervation was produced by complete ...

journal_title：Neural regeneration research

authors： Li Y,Cheng JX,Yang HH,Chen LP,Liu FJ,Wu Y,Fan M,Wu HT

更新日期：2021-07-01 00:00:00

abstract：:Three-dimensional (3D) histology utilizes tissue clearing techniques to turn intact tissues transparent, allowing rapid interrogation of tissue architecture in three dimensions. In this article, we summarized the available tissue clearing methods and classified them according to their physicochemical principles of ope...

journal_title：Neural regeneration research

authors： Lai HM,Ng HM,Wu W

更新日期：2017-01-01 00:00:00

abstract：:Neonatal hypoxic-ischemic encephalopathy is a serious neurological disease, often resulting in long-term neurodevelopmental disorders among surviving children. However, whether these neurodevelopmental issues can be passed to offspring remains unclear. The right common carotid artery of 7-day-old parental-generation r...

journal_title：Neural regeneration research

authors： Xue LL,Wang F,Niu RZ,Tan YX,Liu J,Jin Y,Ma Z,Zhang ZB,Jiang Y,Chen L,Xia QJ,Chen JJ,Wang TH,Xiong LL

更新日期：2020-09-01 00:00:00

abstract：:Spinal cord injury is a major cause of disability with devastating neurological outcomes and limited therapeutic opportunities, even though there are thousands of publications on spinal cord injury annually. There are two major types of spinal cord injury, transaction of the spinal cord and spinal cord contusion. Both...

journal_title：Neural regeneration research

authors： Ju G,Wang J,Wang Y,Zhao X

更新日期：2014-04-15 00:00:00

abstract：:Anti-inflammatory and anti-oxidant agents can alleviate ischemic cerebral injury. The immunomodulary drug Setarud, which is composed of herbal extracts including Rosa canina, Urtica dioica and Tanacetum vulgare, supplemented with selenium exhibits anti-inflammatory and anti-oxidant properties. Therefore, we hypothesiz...

journal_title：Neural regeneration research

authors： Vafaee F,Zangiabadi N,Pour FM,Dehghanian F,Asadi-Shekaari M,Afshar HK

更新日期：2012-09-25 00:00:00

abstract：:Therapeutic strategies for neurological deficits and for promoting nerve regeneration after peripheral nerve injuries have received much focus in clinical research. Advances in basic research in recent years have increased our understanding of the anatomy of peripheral nerves and the importance of the microenvironment...

journal_title：Neural regeneration research

authors： Liu GY,Jin Y,Zhang Q,Li R

更新日期：2015-06-01 00:00:00

abstract：:A mixture of ibotenic acid and β-amyloid 1-42 was injected into the hippocampus of a rat model of Alzheimer's disease, followed by intragastric administration of a traditional Chinese medicine Buyuan Congnao decoction (main components included radix astragali, radix polygoni multiflori preparata, rhizoma acori talarin...

journal_title：Neural regeneration research

authors： Chen M,Wang J,Ming C

更新日期：2012-03-25 00:00:00

abstract：:Tanshinone IIA, extracted from Salvia miltiorrhiza Bunge, exerts neuroprotective effects through its anti-inflammatory, anti-oxidative and anti-apoptotic properties. This study intravenously injected tanshinone IIA 20 mg/kg into rat models of spinal cord injury for 7 consecutive days. Results showed that tanshinone II...

journal_title：Neural regeneration research

authors： Yang YD,Yu X,Wang XM,Mu XH,He F

更新日期：2017-02-01 00:00:00

abstract：:The present study analyzed changes in Wnt3a expression during differentiation of adipose-derived stem cells into cholinergic neurons. Immunocytochemistry and immunofluorescence revealed significantly increased nestin, neuron-specific enolase, microtubule-associated protein 2, and choline acetyltransferase expression i...

journal_title：Neural regeneration research

authors： Liu B,Deng C,Zhang Y,Zhang J

更新日期：2012-07-05 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in the older population, however, the precise cause of the disease is unknown. The neuropathology is characterized by the presence of aggregates formed by amyloid-β (Aβ) peptide and phosphorylated tau; which is accompanied by progressive impairment of memory...

journal_title：Neural regeneration research

authors： Tapia-Rojas C,Inestrosa NC

更新日期：2018-10-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate post-transcriptional gene expression and contribute to all aspects of cellular function. We previously reported that the activities of several mitochondria-enriched miRNAs regulating inflammation (i.e., miR-142-3p, miR-142-5p, and miR-146a) are altere...

journal_title：Neural regeneration research

authors： Wang WX,Prajapati P,Vekaria HJ,Spry M,Cloud AL,Sullivan PG,Springer JE

更新日期：2021-03-01 00:00:00

abstract：Objective:To evaluate the efficacy and safety of MK-801 and its effect on lesion volume in rat models of acute brain injury. Data Sources:Key terms were "stroke", "brain diseases", "brain injuries", "brain hemorrhage, traumatic", "acute brain injury", "dizocilpine maleate", "dizocilpine", "MK-801", "MK801", "rat", "ra...

journal_title：Neural regeneration research

authors： Yi NX,Zhou LY,Wang XY,Song YJ,Han HH,Zhang TS,Wang YJ,Shi Q,Xu H,Liang QQ,Zhang T

更新日期：2019-11-01 00:00:00

abstract：:Cattle encephalon glycoside and ignotin (CEGI) injection is known as a multi-target neuroprotective drug that contains numerous liposoluble molecules, such as polypeptides, monosialotetrahexosyl ganglioside (GM-1), free amino acids, hypoxanthine and carnosine. CEGI has been approved by the Chinese State Food and Drug ...

journal_title：Neural regeneration research

authors： Zhong J,Li RW,Wang J,Wang Y,Ge HF,Xian JS,Feng H,Tan L

更新日期：2021-02-01 00:00:00

abstract：:Functional recovery after oculomotor nerve injury is very poor. Electrical stimulation has been shown to promote regeneration of injured nerves. We hypothesized that electrical stimulation would improve the functional recovery of injured oculomotor nerves. Oculomotor nerve injury models were created by crushing the ri...

journal_title：Neural regeneration research

authors： Du L,Yang M,Wan L,Wang XH,Li ST

更新日期：2016-10-01 00:00:00

abstract：:Glaucoma has been recently characterized as a member of the group of anoikis-related diseases. Anoikis, a form of apoptosis, can be triggered by the unfastening of adherent junctions present in astrocytes. In those areas of the central nervous system in which the soma of the neurons or their axons and dendrites are me...

journal_title：Neural regeneration research

authors： Carreras FJ

更新日期：2019-06-01 00:00:00

abstract：:Acute brain injury caused by subarachnoid hemorrhage is the major cause of poor prognosis. The pathology of subarachnoid hemorrhage likely involves major morphological changes in the microcirculation. However, previous studies primarily used fixed tissue or delayed injury models. Therefore, in the present study, we us...

journal_title：Neural regeneration research

authors： Yang XM,Chen XH,Lu JF,Zhou CM,Han JY,Chen CH

更新日期：2018-03-01 00:00:00

abstract：:To facilitate gathering information during a psychiatric interview, some psychiatrists advocate augmenting the interview using drugs. Rather than barbiturates, benzodiazepines have been used for drug-assisted interviews. Dissociative amnesia is one of the indications for these interviews. Herein, we present the case o...

journal_title：Neural regeneration research

authors： Seo Y,Shin MH,Kim SG,Kim JH

更新日期：2013-01-15 00:00:00

abstract：:The reconstruction of nerve continuity after traumatic nerve injury is the gold standard in hand surgery. Immediate, tension-free, end-to-end nerve suture ensures the best prognosis. The recovery is mostly promising; however, in a few cases, insufficient outcomes in motor or sensory function are observed. Intra- and e...

journal_title：Neural regeneration research

authors： Krzesniak NE,Sarnowska A,Figiel-Dabrowska A,Osiak K,Domanska-Janik K,Noszczyk BH

更新日期：2021-05-01 00:00:00

abstract：:Central nervous system injury, specifically traumatic brain and spinal cord injury, can have significant long lasting effects. There are no comprehensive treatments to combat the injury and sequalae of events that occurring following a central nervous system trauma. Herein we discuss the potential for the epothilone f...

journal_title：Neural regeneration research

authors： Clark J,Zhu Z,Chuckowree J,Dickson T,Blizzard C

更新日期：2021-04-01 00:00:00