Failure of rectal diclofenac to augment opioid analgesia after cholecystectomy.

Abstract:

:The analgesic efficacy of a single 100-mg suppository of diclofenac sodium given after elective cholecystectomy was studied in 30 healthy patients in a double-blind randomised controlled manner. The mean 24-hour postoperative morphine consumption of the placebo group and the diclofenac group was similar (45 mg). Analysis of the cumulative hourly morphine consumption from the patient-controlled analgesia system failed to show any statistically significant differences between the groups. Peak expiratory flow rate, forced expiratory volume at 1 second and forced vital capacity decreased 24 hours after operation to less than 50% of pre-operative values in both groups. Subjective experiences of pain, nausea and drowsiness assessed by linear analogue scoring were similar in both groups.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Colquhoun AD,Fell D

doi

10.1111/j.1365-2044.1989.tb11101.x

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

57-60

issue

1

eissn

0003-2409

issn

1365-2044

journal_volume

44

pub_type

临床试验,杂志文章,随机对照试验
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    更新日期:1997-06-01 00:00:00

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    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

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  • The effect of pre-emptive acupuncture treatment on analgesic requirements after day-case knee arthroscopy.

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    journal_title:Anaesthesia

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    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1986.tb13274.x

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  • Anaesthesia for fetal surgery.

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    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1984.tb06517.x

    authors: Spielman FJ,Seeds JW,Corke BC

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    journal_title:Anaesthesia

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    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1988.tb09062.x

    authors: Sear JW,Shaw I,Wolf A,Kay NH

    更新日期:1988-03-01 00:00:00

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    pub_type: 杂志文章

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    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

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    doi:10.1046/j.1365-2044.2003.02966.x

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    pub_type: 临床试验,杂志文章,随机对照试验

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    更新日期:1996-08-01 00:00:00

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    journal_title:Anaesthesia

    pub_type: 杂志文章

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    更新日期:1976-05-01 00:00:00

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