Abstract:
:The concept of cognitive reserve (CR) was proposed to account for the discrepancy between levels of brain pathologic process or damage and clinical and cognitive function. We provide a detailed review of prospective longitudinal studies that have investigated the interaction between CR and Alzheimer disease (AD) biomarkers on clinical and cognitive outcomes among individuals with normal cognition at baseline. Current evidence is consistent with the view that higher levels of CR are associated with a delay in the onset of symptoms of mild cognitive impairment and that there may be multiple pathways by which CR exerts its protective effects.
journal_name
Clin Geriatr Medjournal_title
Clinics in geriatric medicineauthors
Soldan A,Pettigrew C,Albert Mdoi
10.1016/j.cger.2019.11.006subject
Has Abstractpub_date
2020-05-01 00:00:00pages
247-263issue
2eissn
0749-0690issn
1879-8853pii
S0749-0690(19)30110-7journal_volume
36pub_type
杂志文章,评审abstract::The use of radioactive isotopes in thyroid evaluation and therapy gives important information in the endocrine assessment of the aged. Thyroid uptake imaging can be used to establish a hypothyroid or hyperthyroid state and can determine the functional status of a palpable nodule. Investigational agents, such as T1 201...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
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abstract::This article discusses the usefulness of neuropsychological testing in AD, as an adjunct to the diagnosis, as a means of the evaluation of progression, and response to treatment. Clinical neuropsychological tests that have direct relevance to AD are reviewed, with particular emphasis on recently developed tests of mem...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
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journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
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journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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journal_title:Clinics in geriatric medicine
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