Abstract:
:Objective: To analyze the incidence of acute alcoholic pancreatitis and of severe alcoholic liver disease (ALD) and its association with per capita alcohol consumption with identification of both alcoholic cirrhosis (AC) and severe alcoholic hepatitis (AH), in a population-based setting.Methods: A search was undertaken in diagnoses database for diagnostic codes in order to find patients hospitalized with incident acute alcoholic pancreatitis (AP) and alcoholic liver disease in Iceland in 2001-2015. Diagnoses were verified in all patients who were retrospectively reviewed. Those with ALD had either AC or AH. Alcohol sales during the study period were obtained from Statistics Iceland.Results: Overall, 273 patients with acute AP, mean age at diagnosis 50 (14) years, 74% males and 159 patients with ALD, mean age 57 (11) years, 73% males, were identified. Mean per capita alcohol consumption was 6.95 (0.4) liters and increased by 21% over the study period. The annual incidence of AP increased from 4.2 per 100.000 to 9.5 and ALD from 1.6 to 6.1 per 100.000. Trend analysis showed a significant annual increase of 7% (RR 1.07, 95%CI 1.04-1.10) for AP and an annual increase of 10.5% (RR 1.10, 95%CI 1.06-1.15) for ALD. The increase was only significant in males.Conclusions: Increase per capita alcohol consumption over a 15 year study period was associated with an increase in the incidence of severe alcoholic liver disease and alcohol-related acute pancreatitis in males but not in females.
journal_name
Scand J Gastroenteroljournal_title
Scandinavian journal of gastroenterologyauthors
Hauksson K,Arnardottir M,Agustsson AS,Magnusdottir BA,Baldursdottir MB,Lund SH,Kalaitzakis E,Björnsson ESdoi
10.1080/00365521.2020.1751874subject
Has Abstractpub_date
2020-05-01 00:00:00pages
615-620issue
5eissn
0036-5521issn
1502-7708journal_volume
55pub_type
杂志文章abstract:OBJECTIVE:The incidence of inflammatory bowel disease (IBD) in Europe has increased significantly. At least a fourth of patients are children. Mannan-binding lectin (MBL) is believed to be an important component of innate immunity, acting as an opsonin and activator of the lectin pathway (LP) of complement. The data re...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365521.2011.594087
更新日期:2011-10-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365521.2011.615858
更新日期:2011-12-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1080/00365521.2016.1208270
更新日期:2016-12-01 00:00:00
abstract::An experimental model of extrahepatic cholestasis in the rat, using a microsurgical technique, is described. Sixteen days postoperatively all of the animals (n = 10) were alive and had hepatomegaly, splenomegaly, jaundice, and hyperbilirubinemia. The use of this technique prevents the development of hepatic cysts and ...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365529309096038
更新日期:1993-01-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章,随机对照试验
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更新日期:2019-10-01 00:00:00
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doi:10.3109/00365521.2016.1141433
更新日期:2016-07-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365528109181969
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journal_title:Scandinavian journal of gastroenterology
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doi:10.1080/00365520410004433
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journal_title:Scandinavian journal of gastroenterology
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journal_title:Scandinavian journal of gastroenterology
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更新日期:2017-03-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章,多中心研究
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更新日期:2017-12-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
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doi:10.1080/00365520701320687
更新日期:2007-10-01 00:00:00
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doi:10.3109/00365528809090770
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journal_title:Scandinavian journal of gastroenterology
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doi:10.1080/00365520600880989
更新日期:2007-03-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1993-03-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/00365520510023297
更新日期:2005-09-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:
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doi:10.3109/00365528809090195
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journal_title:Scandinavian journal of gastroenterology
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doi:
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1987-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1080/00365520802321170
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journal_title:Scandinavian journal of gastroenterology
pub_type: 临床试验,杂志文章
doi:10.3109/00365528509091658
更新日期:1985-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-03-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2002-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2008-01-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365528309182091
更新日期:1983-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
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