Fronto-thalamic structural and effective connectivity and delusions in schizophrenia: a combined DTI/DCM study.

abstract：:Some experiments, reported in detail elsewhere, on the effects of mother-infant separation in rhesus monkeys are here reviewed and compared. They involved 4 groups--one in which mothers were removed for 13 days leaving the infant in the social group; one in which infants were removed; one in which mothers and infants ...

journal_title：Psychological medicine

authors： Hinde RA,Mcginnis L

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Excessive worry is required by DSM-IV, but not ICD-10, for a diagnosis of generalized anxiety disorder (GAD). No large-scale epidemiological study has ever examined the implications of this requirement for estimates of prevalence, severity, or correlates of GAD. METHOD:Data were analyzed from the US Nationa...

journal_title：Psychological medicine

authors： Ruscio AM,Lane M,Roy-Byrne P,Stang PE,Stein DJ,Wittchen HU,Kessler RC

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Attention deficit hyperactivity disorder (ADHD) often, but not always, persists into adulthood. Investigations of the associations between clinical and biological markers of persistence can shed light on causal pathways. It has been proposed that compensatory improvements in executive neuropsychological func...

journal_title：Psychological medicine

authors： Coghill DR,Hayward D,Rhodes SM,Grimmer C,Matthews K

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Results of previous research examining long-term residual effects of marijuana use on cognition are conflicting. A major methodological limitation of prior studies is the inability to determine whether differences between users and non-users are due to differences in genetic vulnerability preceding drug use ...

journal_title：Psychological medicine

authors： Lyons MJ,Bar JL,Panizzon MS,Toomey R,Eisen S,Xian H,Tsuang MT

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Early Intervention in Psychosis Services (EIS) for young people in England experiencing first-episode psychosis (FEP) were commissioned in 2002, based on an expected incidence of 15 cases per 100 000 person-years, as reported by schizophrenia epidemiology in highly urban settings. Unconfirmed reports from EI...

journal_title：Psychological medicine

authors： Cheng F,Kirkbride JB,Lennox BR,Perez J,Masson K,Lawrence K,Hill K,Feeley L,Painter M,Murray GK,Gallagher O,Bullmore ET,Jones PB

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Neuroticism has been shown to increase the risk of depression whereas extraversion is associated with a reduction of risk. These personality traits play a central role in aetiological theories of affective disorder but their role in schizophrenia is unclear. In this study, the risk for schizophrenia associat...

journal_title：Psychological medicine

authors： Van Os J,Jones PB

更新日期：2001-08-01 00:00:00

abstract：:A survey over 2 years of all Police Referrals (Section 136 of the Mental Health Act 1983) in an inner-city health district identified 163 cases, with a core group of repeat referrals. Previous psychiatric admissions, a diagnosis of schizophrenia, social deprivation, and a bias towards young men of Afro-Caribbean ethni...

journal_title：Psychological medicine

authors： Turner TH,Ness MN,Imison CT

更新日期：1992-08-01 00:00:00

abstract：:Diffuse loss of cortical volume and ventricular enlargement have been demonstrated in schizophrenia using imaging. In addition, histological studies have provided evidence that the number of neurons in the medial temporal lobe structures is reduced and that the cytoarchitecture is abnormal. In an attempt to correlate ...

journal_title：Psychological medicine

authors： Maier M,Ron MA,Barker GJ,Tofts PS

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Prosocial emotions related to self-blame are important in guiding human altruistic decisions. These emotions are elevated in major depressive disorder (MDD), such that MDD has been associated with guilt-driven pathological hyper-altruism. However, the impact of such emotional impairments in MDD on different ...

journal_title：Psychological medicine

authors： Pulcu E,Thomas EJ,Trotter PD,McFarquhar M,Juhasz G,Sahakian BJ,Deakin JF,Anderson IM,Zahn R,Elliott R

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Patients may present with cognitive impairment in the euthymic phase of affective disorder, but it is unclear whether the impairment is prevalent before onset of the illness. The aim of the present study was to examine the hypothesis that genetic liability to affective disorder is associated with cognitive i...

journal_title：Psychological medicine

authors： Christensen MV,Kyvik KO,Kessing LV

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The phenotypic stability of avoidant personality disorder (AVPD) and obsessive-compulsive personality disorder (OCPD) has previously been found to be moderate. However, little is known about the longitudinal structure of genetic and environmental factors for these disorders separately and jointly, and to wha...

journal_title：Psychological medicine

authors： Gjerde LC,Czajkowski N,Røysamb E,Ystrom E,Tambs K,Aggen SH,Ørstavik RE,Kendler KS,Reichborn-Kjennerud T,Knudsen GP

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The Psychiatric Genomics Consortium (PGC) has made major advances in the molecular etiology of MDD, confirming that MDD is highly polygenic. Pathway enrichment results from PGC meta-analyses can also be used to help inform molecular drug targets. Prior to any knowledge of molecular biomarkers for MDD, drugs ...

journal_title：Psychological medicine

authors： Docherty AR,Moscati A,Bigdeli TB,Edwards AC,Peterson RE,Adkins DE,Anderson JS,Flint J,Kendler KS,Bacanu SA

更新日期：2020-04-01 00:00:00

abstract：:Principal component analysis was applied to data relating to depressive experiences collected from a general population sample. The structure of depression found in the general population showed strong similarities to that found in the psychiatric population. There were, however, important differences. Four substantia...

journal_title：Psychological medicine

authors： Cooke DJ

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:Objective binge eating (OBE) and self-induced vomiting (SIV) occur and co-occur across a range of eating disorders but the extent to which the risk factors for these two behaviours overlap is unclear. Examination of this overlap was the focus of the current report. METHOD:A population of female Australian t...

journal_title：Psychological medicine

authors： Wade TD,Treloar S,Martin NG

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Genetic studies of single gene variants have been criticized as providing a simplistic characterization of the genetic basis of illness risk that ignores the effects of other variants within the same biological pathways. Of candidate biological pathways for schizophrenia (SZ), the cell adhesion molecule (CAM...

journal_title：Psychological medicine

authors： Hargreaves A,Anney R,O'Dushlaine C,Nicodemus KK,Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ).,Wellcome Trust Case Control Consortium 2.,Gill M,Corvin A,Morris D,Donohoe G

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Although impaired recognition of affective facial expressions has been conclusively linked to antisocial behavior, little is known about the modifiability of this deficit. This study investigated whether and under which circumstances the proposed perceptual insensitivity can be addressed with a brief implici...

journal_title：Psychological medicine

authors： Schönenberg M,Christian S,Gaußer AK,Mayer SV,Hautzinger M,Jusyte A

更新日期：2014-04-01 00:00:00

abstract：:Clinical psychiatric and medical assessments were carried out on a randomly selected sample of Australian prisoners of war captured by the Japanese in 1942 and a sample of combatants from Pacific theatres of war who were not captured. Prisoners of war had significantly more anxiety and depressive 'neuroses' and more m...

journal_title：Psychological medicine

authors： Tennant C,Goulston K,Dent O

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:The National Psychiatric Morbidity Survey (NPMS) programme was partly designed to monitor trends in mental disorders, including depression, with comparable data spanning 1993 to 2007. Findings already published from this programme suggest that concerns about increasing prevalence of common mental disorders (...

journal_title：Psychological medicine

authors： Spiers N,Brugha TS,Bebbington P,McManus S,Jenkins R,Meltzer H

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Most studies underline the contribution of heritable factors for psychiatric disorders. However, heritability estimates depend on the population under study, diagnostic instruments, and study designs that each has its inherent assumptions, strengths, and biases. We aim to test the homogeneity in heritability...

journal_title：Psychological medicine

authors： Pettersson E,Lichtenstein P,Larsson H,Song J,Attention Deficit\/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Oral contraceptive use has been previously associated with an increased risk of suicidal behavior in some, but not all, samples. The use of large, representative, longitudinally-assessed samples may clarify the nature of this potential association. METHODS:We used Swedish national registries to identify wom...

journal_title：Psychological medicine

authors： Edwards AC,Lönn SL,Crump C,Mościcki EK,Sundquist J,Kendler KS,Sundquist K

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:The effects of antidepressants for treating depressive disorders have been overestimated because of selective publication of positive trials. Reanalyses that include unpublished trials have yielded reduced effect sizes. This in turn has led to claims that antidepressants have clinically insignificant advanta...

journal_title：Psychological medicine

authors： Cuijpers P,Turner EH,Mohr DC,Hofmann SG,Andersson G,Berking M,Coyne J

更新日期：2014-03-01 00:00:00

abstract：:This paper presents the results of a study of unemployment among British Asians living in the north of England. The sample comprises 139 employed and unemployed men. Using standardized psychological questionnaires with a semi-structured interview schedule, the psychological consequences of unemployment are examined in...

journal_title：Psychological medicine

authors： Shams M,Jackson PR

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:The Met allele of the catechol-O-methyltransferase (COMT) valine-to-methionine (Val158Met) polymorphism is known to affect dopamine-dependent affective regulation within amygdala-prefrontal cortical (PFC) networks. It is also thought to increase the risk of a number of disorders characterized by affective mo...

journal_title：Psychological medicine

authors： Lelli-Chiesa G,Kempton MJ,Jogia J,Tatarelli R,Girardi P,Powell J,Collier DA,Frangou S

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Men sexually interested in children of a specific combination of maturity and sex tend to show some lesser interest in other categories of persons. Patterns of men's sexual interest across erotic targets' categories of maturity and sex have both clinical and basic scientific implications. METHOD:We examined...

journal_title：Psychological medicine

authors： Bailey JM,Blanchard R,Hsu KJ,Revelle W

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Studies investigating neurocognitive impairment in subjects with eating disorders (EDs) have reported heterogeneous patterns of impairment and, in some instances, no dysfunction. The present study aimed to define the pattern of neurocognitive impairment in a large sample of bulimia nervosa (BN) patients and ...

journal_title：Psychological medicine

authors： Galderisi S,Bucci P,Mucci A,Bellodi L,Cassano GB,Santonastaso P,Erzegovesi S,Favaro A,Mauri M,Monteleone P,Maj M

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Obsessive-compulsive disorder (OCD) is a chronic, relapsing mental illness. Selective serotonin reuptake inhibitors block serotonin transporters (SERTs) and are the mainstay of treatment for OCD. SERT abnormalities are reported in drug-free patients with OCD, but it is not known what happens to SERT levels d...

journal_title：Psychological medicine

authors： Kim E,Howes OD,Park JW,Kim SN,Shin SA,Kim BH,Turkheimer FE,Lee YS,Kwon JS

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Previous research suggests that genetic influences on disordered eating may be greater in pubertal than pre-pubertal girls. Although these findings are consistent with pubertal activation of genetic influences on disordered eating, earlier studies were unable to directly test this hypothesis. The purpose of ...

journal_title：Psychological medicine

authors： Klump KL,Perkins PS,Alexandra Burt S,McGue M,Iacono WG

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:We examined the prevalence of self-perceived respiratory symptoms (SRS) in the absence of any objective findings of respiratory pathology, and the association of such prevalence with psychological factors and healthcare use in the general population. METHODS:The study was conducted among a nationally repres...

journal_title：Psychological medicine

authors： Selinheimo S,Vasankari T,Jokela M,Kanervisto M,Pirkola S,Suvisaari J,Paunio T

更新日期：2019-01-01 00:00:00

abstract：:Previously employed techniques for the measurement of body image are briefly described, with a short consideration of methodological or procedural limitations associated with each technique. A new procedure is described which employs a simple modification to a standard video camera to produce an image which appears fr...

journal_title：Psychological medicine

authors： Freeman RJ,Thomas CD,Solyom L,Hunter MA

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Excessive worry is a defining feature of generalized anxiety disorder and is present in a wide range of other psychiatric conditions. Therefore, individualized predictions of worry propensity could be highly relevant in clinical practice, with respect to the assessment of worry symptom severity at the indivi...

journal_title：Psychological medicine

authors： Feng C,Cui Z,Cheng D,Xu R,Gu R

更新日期：2019-09-01 00:00:00