Abstract：
OBJECTIVE:Magnetic resonance imaging-guided focused ultrasound (MRgFUS) is a novel and useful treatment for essential tremor (ET); however, the factors impacting treatment outcome are unknown. The authors conducted this study to determine the factors affecting the outcome of MRgFUS. METHODS:From May 2016 through August 2017, 15 patients with ET were admitted to Ohnishi Neurological Center and treated with MRgFUS. To determine the factors impacting treatment outcome, the authors retrospectively studied correlations between the Clinical Rating Scale for Tremor (CRST) improvement rate and age, disease duration, baseline CRST score, skull density ratio (SDR), skull volume, maximum delivered energy, or maximum temperature. RESULTS:The mean CRST score was 18.5 ± 5.8 at baseline and 4.6 ± 5.7 at 1 year. The rate of improvement in the CRST score was 80% ± 22%. Younger age and lower baseline CRST score were correlated with a higher CRST improvement rate (p = 0.025 and 0.007, respectively). To obtain a CRST improvement rate ≥ 50%, a maximum temperature ≥ 55°C was necessary. There was no correlation between SDR and CRST improvement rate (p = 0.658). A lower SDR and higher skull volume required significantly higher maximum delivered energy (p = 0.014 and 0.016, respectively). A higher maximum temperature was associated with a significantly larger lesion volume (p = 0.026). CONCLUSIONS:Younger age and lower baseline CRST score were favorable outcome factors. It is important to assess predictive factors when applying MRgFUS.
journal_name
J Neurosurgjournal_title
Journal of neurosurgeryauthors
Fukutome K,Kuga Y,Ohnishi H,Hirabayashi H,Nakase Hdoi
10.3171/2020.2.JNS192814subject
Has Abstractpub_date
2020-05-01 00:00:00pages
1-6eissn
0022-3085issn
1933-0693pii
2020.2.JNS192814pub_type
杂志文章abstract：OBJECT:The aim of this study was to target immunotoxin treatment to the high-molecular-weight melanoma-associated antigen (HMW-MAA) and thereby examine any changes in the survival of immunodeficient rats with human glioblastoma multiforme (GBM). METHODS:To target treatment specifically to human glioma cells, Pseudomon...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2004.100.2.0320
更新日期：2004-02-01 00:00:00
abstract：:Chondrolipoangioma is a mesenchymoma primarily composed of cartilage, with adipose tissue and vascular elements present in lesser proportions. Chondrolipoangiomas have been reported to occur in the extremities, chest wall, oral soft tissues, mediastinum, uterus and its round ligament, seminal vesicles, and heart. In t...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/jns.2002.97.5.1226
更新日期：2002-11-01 00:00:00
abstract：:The clinical outcomes are described for 247 consecutive cases of arteriovenous malformation (AVM) treated with the gamma knife between April, 1970, and December 31, 1983. Headache resolved in 65 (66.3%) of the 98 patients presenting with this symptom and improved in an additional nine (9.2%). Of 59 patients admitted w...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1992.77.1.0001
更新日期：1992-07-01 00:00:00
abstract：OBJECT:The authors describe their initial results obtained using a skull-mounted trajectory guide for intraoperative magnetic resonance (MR) imaging-guided brain biopsy sampling. The device was used in conjunction with a new methodology known as prospective stereotaxis for surgical trajectory alignment. METHODS:Betwee...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2001.94.1.0067
更新日期：2001-01-01 00:00:00
abstract：:OBJECTIVE Maximum extent of resection (EOR) for lower-grade and high-grade gliomas can increase survival rates of patients. However, these infiltrative gliomas are often observed near or within eloquent regions of the brain. Awake surgery is of known benefit for the treatment of gliomas associated with eloquent region...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2016.9.JNS16152
更新日期：2017-10-01 00:00:00
abstract：OBJECT:The purpose of this study was to evaluate both replication-competent and replication-restricted recombinant vesicular stomatitis virus (VSV) vectors as therapeutic agents for high-grade gliomas by using an organotypic brain tissue slice-glioma coculture system. METHODS:The coculture system involved growing diff...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2004.100.6.1049
更新日期：2004-06-01 00:00:00
abstract：:Six cases of posterior cervical fusion with rib grafts in children are reported. Four of the children had sustained cervical spine injuries in accidents, and two had congenital absence of the odontoid. Three-level fusions (C1-3) were done in four children, and four-level fusions (C1-4) in two. One child died of unrela...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1976.45.2.0211
更新日期：1976-08-01 00:00:00
abstract：:Intraoperative recordings of conducted bipolar epidural somatosensory evoked potentials (SEP's) generated by unilateral common peroneal nerve stimulation have been obtained in 27 patients. The SEP's were multiphasic, 0.3 to 1.5 microV in amplitude, and recorded in 100% of patients with normal cords or in patients with...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1982.57.3.0349
更新日期：1982-09-01 00:00:00
abstract：:The authors studied 31 comatose head-injured patients to assess the clinical usefulness of laser Doppler flowmetry (LDF) in continuous autoregulation monitoring. The LDF probes were placed on the surface of the cerebral cortex. Data on LDF, intracranial pressure (ICP), and arterial blood pressure (ABP) were recorded a...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1997.86.3.0438
更新日期：1997-03-01 00:00:00
abstract：:Seventy-four consecutive patients who had undergone carotid endarterectomy procedures were examined with intravenous digital subtraction angiography (IV-DSA) and duplex ultrasonography (DUS) at intervals ranging from 1 to 14 months postoperatively. Ninety-one percent of the DUS and 74% of the DSA images were of diagno...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1987.66.1.0088
更新日期：1987-01-01 00:00:00
abstract：:OBJECTIVE Patients with Parkinson disease (PD) who undergo subthalamic nucleus (STN) deep brain stimulation (DBS) often develop a deterioration in speech performance, but there is no clear consensus on the specific effects seen or the mechanism involved and little description of the impact of DBS on conversational spe...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2016.5.JNS16243
更新日期：2017-06-01 00:00:00
abstract：:The authors describe a case of nontraumatic atlantoaxial dislocation secondary to acute rheumatic fever, in which there appeared to be fibrous fusion between the axis and the atlas in the subluxed position. The dislocation was reduced by means of combined traction and steroid therapy. Fibrous fusion occurred in the re...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1982.56.1.0139
更新日期：1982-01-01 00:00:00
abstract：:OBJECTIVE In severe traumatic brain injury (TBI), the effects of decompressive craniectomy (DC) on brain tissue oxygen pressure (PbtO2) and outcome are unclear. The authors aimed to investigate whether changes in PbtO2 after DC could be used as an independent prognostic factor. METHODS The authors conducted a retrospe...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2017.1.JNS161840
更新日期：2018-05-01 00:00:00
abstract：:Fifty-nine cases of vertebral hemangioma were seen at the Mayo Clinic between 1980 and 1990. Vertebral hemangiomas were discovered incidentally in 35 patients, while pain was the presenting complaint in 13 patients. Five patients presented directly with progressive neurological deficit requiring surgery, and six patie...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1993.78.1.0036
更新日期：1993-01-01 00:00:00
abstract：:A 54-year-old female presented with multiple episodes of emesis, intractable headaches, worsening balance, and slowly progressive right facial weakness. Imaging demonstrated a 3-cm mass in the left internal capsule and corona radiata region with associated edema, mass effect, and midline shift concerning for high-grad...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2016.7.JNS1690
更新日期：2017-08-01 00:00:00
abstract：:A patient with glioblastoma multiforme of the brain was treated with both intravenous and oral glycerol as well as intravenous mannitol in an attempt to reduce increased intracranial pressure. After an initial lowering of the cerebrospinal fluid (CSF) pressure to near normal values during continuous glycerol administr...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1975.42.2.0226
更新日期：1975-02-01 00:00:00
abstract：:The purpose of this study was to determine the cause of the loss of endothelium-dependent relaxation observed in chronic cerebral vasospasm. A bioassay system was developed to measure the release of endothelium-derived relaxing factor (EDRF) from canine basilar arteries. Subarachnoid hemorrhage (SAH) was induced in do...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1989.70.1.0108
更新日期：1989-01-01 00:00:00
abstract：:OBJECTIVE Hyperperfusion syndrome (HPS) is a notable complication that causes various neurological symptoms after superficial temporal artery (STA)-middle cerebral artery (MCA) bypass surgery for moyamoya disease (MMD). The authors used intraoperative indocyanine green (ICG) videoangiography to measure the change in m...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2016.11.JNS162403
更新日期：2018-05-01 00:00:00
abstract：:Damage to the olfactory nerve during frontotemporal approach to the basal cisternal region has not previously been investigated in a quantified manner. In this retrospective study of 25 patients operated on for ruptured intracranial aneurysms via the frontotemporal route, 22 patients suffered postoperatively from anos...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1990.72.6.0864
更新日期：1990-06-01 00:00:00
abstract：OBJECT:Cellular density is a major factor for change in the apparent diffusion coefficient (ADC). The authors hypothesized that loss of tumor cells after Gamma Knife surgery (GKS) may alter the ADC value and used diffusion weighted MR imaging (DW imaging) to evaluate cellular changes in brain tumors to detect their tre...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：:Two cases of catecholamine-secreting paragangliomas of the base of the skull are described. The patients presented with uncontrollable hypertension and, after investigation, tumors were discovered in the regions of the glomus jugulare and pterygopalatine ganglion, respectively. After cardiovascular stabilization and t...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1987.66.4.0604
更新日期：1987-04-01 00:00:00
abstract：:OBJECT Approximately 250 million surgical procedures are performed annually worldwide, and data suggest that major complications occur in 3%-17% of them. Many of these complications can be classified as avoidable, and previous studies have demonstrated that preoperative checklists improve operating room teamwork and d...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2015.4.JNS142184
更新日期：2016-06-01 00:00:00
abstract：:The T-13 spinal cord segment of dogs was compressed both acutely and chronically by means of a balloon catheter. The vascular permeability to protein was assessed using Evans blue albumin (EBA), and the dorsal column evoked potential recorded to monitor conduction failure. With acute compression sufficient to cause co...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1975.42.2.0155
更新日期：1975-02-01 00:00:00
abstract：OBJECT:The authors investigated early changes in the cerebral arteries of rats that occur after subarachnoid hemorrhage (SAH). METHODS:Messenger RNA was investigated by performing microarray and quantitative real-time polymerase chain reaction (PCR) analyses, and protein expression was shown by performing immunohistoc...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2006.105.3.438
更新日期：2006-09-01 00:00:00
abstract：OBJECT:The goal of this study was to establish the therapeutic window during which delayed therapy with MgSO4 improves neurological motor outcome in rats that have suffered severe traumatic axonal brain injury. METHODS:Severe brain injury was induced in male Sprague-Dawley rats by using the impact-acceleration model o...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1999.90.3.0504
更新日期：1999-03-01 00:00:00
abstract：OBJECT:The transbasal approach (TBA) is an anterior skull base approach, which provides access to the anterior skull base, sellar-suprasellar region, and clivus. The TBA typically involves a bifrontal craniotomy with orbital bar and/or nasal bone osteotomies performed in 2 separate steps. The authors explored the feasi...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2014.8.JNS132609
更新日期：2014-12-01 00:00:00
abstract：OBJECT:Twenty-nine nonimmunocompromised patients with primary central nervous system (CNS) lymphoma were treated with high-dose methotrexate (MTX) therapy followed by irradiation. The authors investigated the correlation of infusion schedules with MTX penetration into cerebrospinal fluid (CSF), tumor response, and surv...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1999.91.2.0221
更新日期：1999-08-01 00:00:00
abstract：:The author presents a follow-up review of 61 patients with subarachnoid hemorrhage (SAH) and at least two intracranial artery aneurysms in whom only the ruptured aneurysm had been clipped. During a 10-year follow-up period, seven patients bled from a previously unruptured aneurysm; four of the hemorrhages were fatal. ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1981.55.4.0524
更新日期：1981-10-01 00:00:00
abstract：:Intraventricular pressure (IVP) is increased in the early stages of acute hydrocephalus. Pressure falls, however, when compensatory routes for cerebrospinal fluid (CSF) absorption develop. In order to better understand the pathophysiology of acute hydrocephalus, the authors performed ventriculocisternal perfusions on ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1983.59.4.0606
更新日期：1983-10-01 00:00:00
abstract：:OBJECTIVE Stereotactic radiosurgery (SRS) with or without whole-brain radiotherapy can be used to achieve local control (> 90%) for small brain metastases after resection. However, many brain metastases are unsuitable for SRS because of their size or previous treatment, and whole-brain radiotherapy is associated with ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2016.4.JNS152530
更新日期：2017-06-01 00:00:00
