Abstract:
:BACKGROUND: Although the understanding of hypobaric hypoxia is increasing, it remains a hazard in aviation medicine. This study examined the feasibility of detecting voice markers sensitive to acute hypobaric hypoxia in an early presymptomatic (PRE-SYMP) stage.METHOD: Eight subjects qualified with hypobaric training completed a series of standardized speech tests in a hypobaric chamber at 20,000 ft and 25,000 ft (6096 and 7620 m) of altitude. Voice response patterns were analyzed in terms of fundamental frequency (F0), F0 range, and voice onset time (VOT). We hypothesized a PRE-SYMP compensatory stage in voice reactivity.RESULTS: There was a different dose-response reactivity course at 20,000 ft vs. 25,000 ft, nonlinear to altitude. At 20,000 ft, our hypothesis was confirmed. In comparison to sea level, a PRE-SYMP compensatory stage could be distinguished, characterized by a decreased F0 range, decreased VOT, and increased F0. During a transitional (TRANS) stage, in comparison with sea level, the F0-range reset, VOT decreased, and F0 increased. During a symptomatic (SYMP) stage, F0 increased, F0 range increased, and VOT decreased. At 25,000 ft, in comparison to sea level, voice reactivity showed increased F0 and F0 range and decreased VOT in a PRE-SYMP stage and increased F0 and F0 range in the SYMP stage.DISCUSSION: The compensatory PRE-SYMP stage is suggested to be the expression of ongoing bottom-up and top-down regulatory mechanisms, whereas the 25,000-ft results are interpreted as a combination of tonic and phasic voice reactivity. This tonic component needs to be foreseen in sea level baseline measures.Van Puyvelde M, Neyt X, Vanderlinden W, Van den Bossche M, Bucovaz T, De Winne T, Pattyn N. Voice reactivity as a response to acute hypobaric hypoxia at high altitude. Aerosp Med Hum Perform. 2020; 91(6):471-478.
journal_name
Aerosp Med Hum Performjournal_title
Aerospace medicine and human performanceauthors
Van Puyvelde M,Neyt X,Vanderlinden W,Van den Bossche M,Bucovaz T,De Winne T,Pattyn Ndoi
10.3357/AMHP.5390.2020subject
Has Abstractpub_date
2020-06-01 00:00:00pages
471-478issue
6eissn
2375-6314issn
2375-6322journal_volume
91pub_type
杂志文章abstract::BACKGROUND: Although oropharyngeal squamous cell papilloma (OSCP) is not uncommon in the general population, reports of OSCP in aviators are rare. This case report serves as a call for flight surgeons to consider all oropharyngeal pathology as a potential source of airway compromise during flight, and highlights regio...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5429.2019
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION:There is good evidence that long term exposure to ultraviolet (UV) radiation increases the risk of cataracts. The 'blue light hazard' is considered a risk factor for retinal changes similar to those seen in macular degeneration. Previous studies ascertaining the prevalence of radiation related ocular disea...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4357.2015
更新日期:2015-11-01 00:00:00
abstract::BACKGROUND: Human fatigue is an important factor within aviation, leading organizations to develop strategies to assess and mitigate associated risks. The U.S. Air Force's Air Mobility Command (AMC) conducted the current pilot study to assess fatigue-related risks and issues in mobility operations. Specifically, we ex...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5396.2020
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Shoulder injuries due to working inside the space suit are some of the most serious and debilitating injuries astronauts encounter. Space suit injuries occur primarily in the Neutral Buoyancy Laboratory (NBL) underwater training facility due to accumulated musculoskeletal stress. We quantitatively explored...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4220.2015
更新日期:2015-07-01 00:00:00
abstract::INTRODUCTION: We examined aircrew fatigue during the following flight duty periods (FDPs) mentioned in the European Union (EU) Flight Time Limitations (FTLs): night FDPs longer than 10 h and FDPs typical of disruptive schedules (early starts, late finishes, and nights). An alternative way of classifying night FDPs was...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5561.2020
更新日期:2020-08-01 00:00:00
abstract::INTRODUCTION: The use of systemic corticosteroids for upper respiratory tract infections has become increasingly common, but remains controversial. Given their purported ability to decrease duration of illness and hasten recovery, systemic corticosteroids offer an attractive treatment modality for flight surgeons desi...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5548.2020
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Mild hypercapnia combined with a cephalad fluid shift [e.g., that occurring during spaceflight or laparoscopic surgery with head-down tilt (HDT)] might affect cerebral autoregulation. However, no reports have described the effects of the combination on dynamic cerebral autoregulation. Therefore, we tested th...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4870.2017
更新日期:2017-09-01 00:00:00
abstract::BACKGROUND: Motion sickness is a problem for many; however, it is especially pressing for military personnel who need to operate in life and death environments. The current study investigated the underlying cause of motion sickness by testing postural instability theory.METHODS: Subjects experienced realistic motion p...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5539.2020
更新日期:2020-09-01 00:00:00
abstract:INTRODUCTION:The greater sensitivity of extended high-frequency audiometry (EHFA) than conventional audiometry (CA) for identifying early changes in hearing has been well documented in previous literature. However, no studies about EHFA were conducted on civilian pilots. The aim of this study was to investigate the use...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5029.2018
更新日期:2018-07-01 00:00:00
abstract::INTRODUCTION: Despite the clear need for understanding how pilot sleep affects performance during long-range (LR; 12-16h) and ultra-long-range (ULR; 16+h) flights, the scientific literature on the effects of sleep loss and circadian desynchronization on pilots' sleep in commercial aviation is sparse.METHODS: We assess...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5117.2019
更新日期:2019-02-01 00:00:00
abstract::BACKGROUND: Frequent migraine headaches are disabling and aeromedically disqualifying. Four new monoclonal antibody medications, targeting calcitonin gene-related peptide (CGRP), have been approved by the U.S. Food and Drug Administration (FDA) since 2018, with more expected in the coming years. These medications pres...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5688.2020
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Cartilage tissue engineering is a growing field due to the lack of regenerative capacity of native tissue. The use of bioreactors for cartilage tissue engineering is common, but the results are controversial. Some studies suggest that microgravity bioreactors are ideal for chondrogenesis, while others show t...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4743.2017
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Artificial hypergravity has been proposed to prevent or treat various forms of physiological deconditioning experienced during spaceflight. We have previously reported that cerebral blood flow decreased at 15-21 min of +1.5-Gz centrifugation without decreases in arterial pressure at heart level. We reanalyze...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5106.2018
更新日期:2018-09-01 00:00:00
abstract::BACKGROUND: High-altitude decompression sickness (HADCS) is a rare condition that has been associated with aircraft accidents. To the best of our knowledge, the present paper is the first case report of a patient treated for severe HADCS using recompression therapy and veno-venous extracorporeal oxygenation (VV-ECMO) ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5457.2020
更新日期:2020-02-01 00:00:00
abstract::Martin BR. You're the flight surgeon: West Nile virus neuroinvasive disease. Aerosp Med Hum Perform. 2016; 87(11):976-979. ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4715.2016
更新日期:2016-01-01 00:00:00
abstract::On ISS missions and explorer class missions, unexpected medical and surgical emergencies could be disastrous. Lack of ability to rapidly assess and make critical decisions affects mission capability. Current imaging modalities on ISS consist only of ultrasound. There are many acute diagnoses which ultrasound alone can...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4110.2015
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Laser devices are ubiquitous in everyday operations. These devices pose a hazard to the eye and numerous injuries have been documented. However, there lies a misunderstanding in the propensity to damage aircrews' eyes during an exposure. Patient encounters and article review is presented in hopes to raise aw...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4889.2017
更新日期:2017-11-01 00:00:00
abstract::INTRODUCTION: This study explores the safety risk due to delayed detection of hazardous health conditions that would result from increasing the duration of U.S. first-class aeromedical certificates from 6 mo to 12 mo for pilots ages 40 yr old through 60 yr old.METHODS: All pilots who submitted a U.S. first-class appli...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5268.2019
更新日期:2019-05-01 00:00:00
abstract:INTRODUCTION:This study explores the U.S. experience with waivers for insulin treatment for third-class medical certificates. From 1997 through 2014, the Federal Aviation Administration (FAA) approved an estimated 1500 waivers for insulin-treated diabetes with a total of 450 active waivers as of December 31, 2014. Thes...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4726.2017
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:This paper discusses a special kind of a sensory illusion-the Giant Hand illusion-that was experienced during an exercise on a flight simulator equipped with a VR headset. In the first part we describe spatial disorientation and the function of the vestibular apparatus during flight and its consequences. In ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5008.2018
更新日期:2018-06-01 00:00:00
abstract::Wolf SJ. You're the flight surgeon: lateral epicondylitis. Aerosp Med Hum Perform. 2015; 86(12):1077-1080. ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4312.2015
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:This study aimed to investigate the feasibility of determining the physiological parameters associated with the ability to complete simulated exploration type tasks at metabolic rates which might be expected for lunar and Martian ambulation. METHODS:Running V̇O2max and gas exchange threshold (GET) were meas...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4399.2016
更新日期:2016-04-01 00:00:00
abstract:INTRODUCTION:To ensure flight safety military aircrew undergo regular clinical and occupational assessment. Coronary artery calcium scoring (CACS) has been established as an imaging modality to noninvasively assess coronary artery disease (CAD). CT coronary angiography (CTCA) potentially offers a more accurate assessme...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4636.2017
更新日期:2017-02-01 00:00:00
abstract::OBJECTIVE: The goal of this study was to estimate noise exposure and hearing impairments in Swedish military pilots. It also aimed to analyze possible relations between noise exposure and hearing impairments.METHODS: The study group was an open cohort of 337 male pilots. They were longitudinally followed with pure ton...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5353.2019
更新日期:2019-09-01 00:00:00
abstract:INTRODUCTION:Recent physiological incidents involving pilots of high performance fighter aircraft have raised the question of whether inadvertent, short bursts of significantly reduced oxygen could negatively impact real-time performance. This study evaluated normobaric, real-time performance in the setting of transien...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4041.2015
更新日期:2015-02-01 00:00:00
abstract:INTRODUCTION:Although there are numerous studies that demonstrate that color vision deficient (CVD) individuals perform less well than color vision normal (CVN) individuals in tasks that require discrimination or identification of colored stimuli, there remains a need to quantify the relationship between the type and s...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4630.2016
更新日期:2016-01-01 00:00:00
abstract::BACKGROUND: Decompression sickness is a condition that results from an abrupt change from a higher to a lower pressure. It is described most commonly in divers; however, it can occur in aviation incidents, which this case report will discuss.CASE REPORT: Following an acute cabin depressurization incident, 36 patients ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5142.2018
更新日期:2018-12-01 00:00:00
abstract::INTRODUCTION: In-flight medical events (IMEs), although rare, are challenging due to the limited onboard resources and the time needed to reach an airport. Cabin crewmembers (CCMs) are trained to provide first aid, but their effectiveness has not been appropriately studied.METHODS: IMEs occurring in the biggest airlin...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5715.2021
更新日期:2021-01-01 00:00:00
abstract:INTRODUCTION:The Ishihara plates are commonly used as an initial occupational screening test for color vision. While effective at detecting red-green deficiencies, the color deficient subject can learn the test using different techniques. Some medical standards such as the European Aviation Safety Agency (EASA) require...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4257.2015
更新日期:2015-08-01 00:00:00
abstract::INTRODUCTION: Hypertension, also known as high blood pressure, is the "silent killer" and may lead to more severe conditions if left unmanaged. Hypertension in service members of the U.S. military has the potential to negatively impact readiness. The aim of this study was to assess the potential impact to readiness of...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5229.2019
更新日期:2019-04-01 00:00:00