Eye-sparing Treatment of Localized Orbital Medulloepithelioma With Neoadjuvant Chemoradiation.

Abstract:

:A 9-year-old girl presented with a 3-day history of progressive proptosis accompanied by transient discomfort and blurry vision in the OD. MRI revealed a heterogeneously enhancing intraconal lesion that partially encased and displaced the optic nerve. There was no intraocular or intracranial involvement, nor were there signs of distant metastasis. Histopathologic evaluation and immunohistochemistry were consistent with orbital medulloepithelioma. The patient received 4 cycles of chemoradiation per a retinoblastoma protocol. Repeat MRI scans showed significant tumor regression, and further surgical debulking was performed. There has been no evidence of recurrence for over 14 months. Herein, the authors describe an eye-sparing, multimodal treatment of a rare case of localized orbital medulloepithelioma.

authors

Gallo RA,Shoag J,Johnson TE,Solomon DA,Perry A,Podda A,Lee JY,Rong AJ

doi

10.1097/IOP.0000000000001703

subject

Has Abstract

pub_date

2021-01-01 00:00:00

pages

e13-e16

issue

1

eissn

0740-9303

issn

1537-2677

pii

00002341-202101000-00035

journal_volume

37

pub_type

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