An apple a day won't keep the doctor away: presentation, treatment, and outcome in pediatric apple aspirations.

Abstract:

INTRODUCTION:Foreign body (FB) aspiration is a frequent and preventable source of morbidity and mortality, especially in children under 4 years of age. Few comprehensive studies exist on presentation and outcome of apple aspirations in children. METHODS:In a retrospective analysis of bronchoscopy records of a tertiary medical care center from January 2007 to August 2019, we identified pediatric cases of suspected apple aspirations. RESULTS:A total of 11 suspected apple aspirations were identified (observation time 12.7 years, n = 5858 bronchoscopies, n = 226 interventions due to suspected FB aspirations in total). The mean age of patients was 24 months (standard error mean, 7 months; range, 8-83 months), and 6 out of 11 cases (55%) were male. Bronchoscopy confirmed apple aspiration in n = 6/11 cases (55%). In n = 2/11 cases (18%), a bite of the apple was located in the esophagus causing significant tracheal narrowing, and in n = 3/11 cases (27%), no FB was found. In all cases of airway FB identification, extraction was successful. Hypersalivation was associated with esophageal FB location, whereas persistent cough, stridor, or dyspnea were associated with airway FB location. Outcomes ranged from complete reconstitution 1 day after bronchoscopy in most cases to hypoxemia with severe brain damage in one patient. DISCUSSION:This analysis shows that apple aspirations are not entirely uncommon in children and may lead to disastrous complications. Typical signs of airway location are persistent cough, stridor or dyspnea, whereas hypersalivation may point toward an esophageal location. In each case of suspected apple aspiration, timely bronchoscopy with possible FB extraction should be performed by an experienced team.

journal_name

Pediatr Pulmonol

journal_title

Pediatric pulmonology

authors

Zychlinsky Scharff A,Schwerk N,Baumann U,Burmester H,Carlens J,Dopfer C,Grewendorf S,Mueller C,Schütz K,Voelker M,Hansen G,Happle C,Wetzke M

doi

10.1002/ppul.24768

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

1697-1704

issue

7

eissn

8755-6863

issn

1099-0496

journal_volume

55

pub_type

杂志文章
  • Blood L-arginine levels in early respiratory distress syndrome.

    abstract::L-arginine is the precursor of nitric oxide which plays an important role on pulmonary circulation and pulmonary vascular tone. Our aim was to compare the levels of L-arginine between infants with respiratory distress syndrome and infants without respiratory distress syndrome and to determine the relationship between ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20326

    authors: Canpolat FE,Yurdakök M,Yiğit S,Korkmaz A,Tekinalp G

    更新日期:2005-12-01 00:00:00

  • Dynamics of spontaneous breathing during patient-triggered partial liquid ventilation.

    abstract::This study evaluates different ventilator strategies during gas (GV) and partial liquid ventilation (PLV) in spontaneously breathing animals. We hypothesized that during PLV, spontaneously breathing animals would self-regulate respiratory parameters by increasing respiratory rate (RR) and minute ventilation (V'E) when...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/(sici)1099-0496(199811)26:5<319::aid-ppul3

    authors: Bendel-Stenzel EM,Mrozek JD,Bing DR,Meyers PA,Connett JE,Mammel MC

    更新日期:1998-11-01 00:00:00

  • Accurate lung volume measurements in vitro using a novel inert gas washout method suitable for infants.

    abstract:BACKGROUND:Multiple breath washout (MBW) in infants presents a number of technical challenges. Conventional MBW is based on simultaneous measurement of flow and gas concentrations. These two signals are aligned and combined to derive expired gas volumes from which lung volumes and measures of ventilation inhomogeneity ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23348

    authors: Shawcross A,Murray CS,Goddard N,Gupta R,Watson S,Horsley A

    更新日期:2016-05-01 00:00:00

  • Benzyl-benzoate foam: effects on mite allergens in mattress, serum and nasal secretory IgE to Dermatophagoides pteronyssinus, and bronchial hyperreactivity in children with allergic asthma.

    abstract::Home mattresses of 24 asthmatic children with house dust mite allergy were sprayed with either benzyl-benzoate foam or placebo in a double blind fashion, 10 days before the children left the residential house for asthmatic children Istituto Pio XII (located in the Italian Alps in an environment free of mites) and went...

    journal_title:Pediatric pulmonology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/ppul.1950180405

    authors: Sette L,Comis A,Marcucci F,Sensi L,Piacentini GL,Boner AL

    更新日期:1994-10-01 00:00:00

  • Congenital lung abnormality quantification by computed tomography: The CLAQ method.

    abstract:INTRODUCTION:To date, no consensus has been reached on the optimal management of congenital lung abnormalities, and factors predicting postnatal outcome have not been identified. We developed an objective quantitative computed tomography (CT) scoring method, and assessed its value for clinical decision-making. METHODS...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.25032

    authors: Hermelijn SM,Dragt OV,Bosch JJ,Hijkoop A,Riera L,Ciet P,Wijnen RMH,Schnater JM,Tiddens HAWM

    更新日期:2020-11-01 00:00:00

  • Ten-year follow up of hydroxychloroquine treatment for ABCA3 deficiency.

    abstract::We present a child with interstitial lung disease (ILD) who was diagnosed with desquamative interstitial pneumonitis following CT thorax and open lung biopsy aged 2 years. Subsequently, surfactant protein gene analysis revealed mutations in the ABCA3 gene. This case of ABCA3 deficient ILD describes a stable clinical c...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.22811

    authors: Williamson M,Wallis C

    更新日期:2014-03-01 00:00:00

  • Efficacy of mycophenolate on lung disease and autoimmunity in children with immunodeficiency.

    abstract::The autoimmune manifestations of primary immunodeficiencies, such as autoimmune lymphoproliferative syndrome (ALPS) and common variable immunodeficiency (CVID), often constitute a great therapeutic challenge and have a significant impact on patients' morbidity and mortality. The most common autoimmune presentations ar...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23757

    authors: Bucciol G,Petrone A,Putti MC

    更新日期:2017-10-01 00:00:00

  • Quality of life in children with CF: Psychometrics and relations with stress and mealtime behaviors.

    abstract:BACKGROUND:The purpose of this study was to evaluate the utility of the Cystic Fibrosis Questionnaire-Revised (CFQ-R) with toddlers and preschool-aged children. Clinically relevant relations between health-related quality of life (HRQOL), stress, and mealtime behaviors have not been examined. It was hypothesized that p...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23149

    authors: Driscoll KA,Modi AC,Filigno SS,Brannon EE,Chamberlin LA,Stark LJ,Powers SW

    更新日期:2015-06-01 00:00:00

  • DRESS syndrome in a patient with cystic fibrosis: A case report.

    abstract::Drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a rare and severe side-effect, mainly described after intake of anticonvulsants, allopurinol, or antibiotics. It usually begins within 2 months after drug introduction. Symptoms include cutaneous rash, hematologic abnormalities, and internal orga...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23567

    authors: Gohy S,Froidure A,Lebecque P

    更新日期:2017-04-01 00:00:00

  • Pulmonary complications after bone marrow transplantation in children: twenty-four years of experience in a single pediatric center.

    abstract::In children, pulmonary sequelae contribute to early and late morbidity after bone marrow transplantation (BMT). Between 1975-1999, we performed 152 BMTs in 138 pediatric patients with malignant and nonmalignant diseases. Allogenic bone marrow was used from 99 HLA identical siblings and from 23 other related or unrelat...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/1099-0496(200011)30:5<393::aid-ppul5>3.0.c

    authors: Griese M,Rampf U,Hofmann D,Führer M,Reinhardt D,Bender-Götze C

    更新日期:2000-11-01 00:00:00

  • Effect of low altitude at the Dead Sea on exercise capacity and cardiopulmonary response to exercise in cystic fibrosis patients with moderate to severe lung disease.

    abstract::Oxygen supplementation may improve exercise tolerance and the physiological response to exercise in cystic fibrosis (CF) patients. Elevated barometric pressure at low altitude is a simple means of increasing the quantity of inspired oxygen. Our objectives were to examine the effect of natural oxygen enrichment (at the...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/ppul.20342

    authors: Falk B,Nini A,Zigel L,Yahav Y,Aviram M,Rivlin J,Bentur L,Avital A,Dotan R,Blau H

    更新日期:2006-03-01 00:00:00

  • Early versus late identification of infants at high risk of developing moderate to severe bronchopulmonary dysplasia.

    abstract::We developed a simple method to identify neonates at high risk of bronchopulmonary dysplasia (BPD) and determined whether early (8 hours) and late (14 days) risk assessment is equally useful. A retrospective cohort design was utilized of subjects enrolled in multi-dose surfactant trials to develop each risk identifica...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1099-0496(199606)21:6<345::AID-PPUL1

    authors: Rozycki HJ,Narla L

    更新日期:1996-06-01 00:00:00

  • The etiology of tracheal mucosal injury in proximal esophageal atresia plus distal tracheoesophageal fistula: an animal study.

    abstract::Tracheal mucosal damage has been reported in autopsy specimens of cases with proximal esophageal atresia and distal tracheoesophageal fistula (EA-TEF) (Gross classification type C). Such changes have not been reported for isolated EA (Gross classification type A). Our hypothesis is that passage of amniotic fluid (AF) ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20490

    authors: Ateş O,Hakgüder G,Olguner M,Ozer E,Akgür FM

    更新日期:2006-11-01 00:00:00

  • Necrotizing sarcoid granulomatosis: a rarity in childhood.

    abstract::Necrotizing sarcoid granulomatosis (NSG) is characterized by pulmonary nodular infiltrates, a typical histology, and a benign clinical course. The etiology and pathogenesis of the disease are still unknown. In childhood, it is extremely rare, with only three reported cases so far. Here we report on an 8-year-old girl,...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.10242

    authors: Heinrich D,Gordjani N,Trusen A,Marx A,Hebestreit H

    更新日期:2003-05-01 00:00:00

  • Ambulatory blood pressure monitoring in Chinese children with obstructive sleep apnea/hypopnea syndrome.

    abstract:OBJECTIVE:Obstructive sleep apnea/hypopnea syndrome (OSAHS) is a common sleep problem. The aim of this study is to investigate the association between OSAHS and blood pressure (BP) in snoring children. METHODS:Snoring children were recruited from January 2009 to December 2010. Clinical history was taken accompanied by...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.22595

    authors: Xu Z,Li B,Shen K

    更新日期:2013-03-01 00:00:00

  • Evaluation and management of pulmonary disease in ataxia-telangiectasia.

    abstract:SUMMARY:Ataxia-telangiectasia (A-T) is a rare autosomal recessive disorder caused by mutations in the ATM gene, resulting in faulty repair of breakages in double-stranded DNA. The clinical phenotype is complex and is characterized by neurologic abnormalities, immunodeficiencies, susceptibility to malignancies, recurren...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21277

    authors: McGrath-Morrow SA,Gower WA,Rothblum-Oviatt C,Brody AS,Langston C,Fan LL,Lefton-Greif MA,Crawford TO,Troche M,Sandlund JT,Auwaerter PG,Easley B,Loughlin GM,Carroll JL,Lederman HM

    更新日期:2010-09-01 00:00:00

  • Hering-Breuer reflex in young asthmatic children.

    abstract::The aim of this study was to assess if the Hering-Breuer reflex could be provoked in young children. Thirty asthmatic children with a mean age of 5.3 years and 18 healthy children with a mean age of 7.0 years were studied. The presence of the reflex was indicated by prolongation of the spontaneous expiratory time foll...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950110412

    authors: Greenough A,Pool J

    更新日期:1991-01-01 00:00:00

  • Inadvertent removal of foreign body via a flexible fiberoptic bronchoscope in a 4-year-old boy.

    abstract::We report the case of a 4-year-old child with an atypical presentation of an aspirated unwitnessed foreign body in the airway. During an attempt to obtain a biopsy of what appeared to be a mucosal growth, the foreign body was removed. This may be the first report of foreign body removal in a child this young, using a ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950180113

    authors: Akhter J,Gaspar M,Bassuk A,Roberts J

    更新日期:1994-07-01 00:00:00

  • Management of empyema in children.

    abstract::The incidence of empyema complicating community-acquired pneumonia is increasing and causes significant childhood morbidity. Pneumococcal infection remains the most common isolated cause in developed countries, with Staphylococcus aureus the predominant pathogen in the developing world. Newer molecular techniques util...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,评审

    doi:10.1002/ppul.20251

    authors: Jaffé A,Balfour-Lynn IM

    更新日期:2005-08-01 00:00:00

  • TNF-alpha, IL-8, soluble ICAM-1, and neutrophils in sputum of cystic fibrosis patients.

    abstract::The cytokines tumor necrosis factor-alpha (TNF-alpha), interleukin-8 (IL-8), and intercellular adhesion molecule-1 (ICAM-1) have important roles in regulating neutrophil migration and the inflammatory response. To determine whether the concentration of these cytokines and soluble ICAM-1 (sICAM-1) in sputum was increas...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1099-0496(199601)21:1<11::AID-PPUL2>

    authors: Salva PS,Doyle NA,Graham L,Eigen H,Doerschuk CM

    更新日期:1996-01-01 00:00:00

  • Lung clearance index: normal values, repeatability, and reproducibility in healthy children and adolescents.

    abstract::There is increasing interest in using the Multiple Breath Washout technique and the lung clearance index (LCI) for detecting early pulmonary changes, for example, in cystic fibrosis lung disease. However, there are still limited data regarding equipment specific reference ranges, repeatability and reproducibility. The...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21093

    authors: Fuchs SI,Eder J,Ellemunter H,Gappa M

    更新日期:2009-12-01 00:00:00

  • Do New Zealand children with non-cystic fibrosis bronchiectasis show disease progression?

    abstract:BACKGROUND:There is minimal literature available on the long-term outcome of pediatric non-cystic fibrosis (CF) bronchiectasis. AIM:To document 5-year outcomes of children with chest computerized tomography (CT) scan diagnosed bronchiectasis from a tertiary New Zealand (NZ) respiratory clinic. METHODS:Review of a cli...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21331

    authors: Munro KA,Reed PW,Joyce H,Perry D,Twiss J,Byrnes CA,Edwards EA

    更新日期:2011-02-01 00:00:00

  • Use of exercise in the management of cystic fibrosis: short communication about a survey of cystic fibrosis referral centers.

    abstract::A survey of 47 cystic fibrosis referral centers was conducted to study the use of exercise in the management of patients with cystic fibrosis (CF). A questionnaire with 5 brief questions concerning the prescription and application of exercise therapy was sent to the first 47 centers (38.5%) listed in the 1988 CF Found...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950100313

    authors: Kaplan TA,ZeBranek JD,McKey RM Jr

    更新日期:1991-01-01 00:00:00

  • Nocturnal dry cough in the first 7 years of life is associated with asthma at school age.

    abstract:BACKGROUND:Childhood wheeze is an important, well-known risk factor for asthma, yet little is known about the contribution of nocturnal dry cough. We investigated the association of nocturnal dry cough at ages 1-7 years with doctor-diagnosed asthma at 8 years of age, both in the presence and absence of wheeze. METHODS...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23092

    authors: Boudewijn IM,Savenije OE,Koppelman GH,Wijga AH,Smit HA,de Jongste JC,Gehring U,Postma DS,Kerkhof M

    更新日期:2015-09-01 00:00:00

  • Caffeine potentiates airway responsiveness in the neonatal lamb.

    abstract::In contrast to its effect on airway smooth muscle in the adult, in vitro studies have shown that caffeine significantly increases active tension in airway smooth muscle in the neonatal lamb. To determine if caffeine has a physiological effect on airway function during early development, we studied the effect of caffei...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950120106

    authors: Keklikian EN,Wolfson MR,Shaffer TH

    更新日期:1992-01-01 00:00:00

  • CF: an X-ray database to assess effect of aerosolized tobramycin.

    abstract::This paper assesses the effectiveness of aerosolized tobramycin (TOBI) on cystic fibrosis (CF) lung disease, using a radiologic tool. The published tool, the age-based severity curve (ABS), is derived from Brasfield scoring of chest X-rays (CXR). This study evaluates both the usefulness of the ABS as an assessment too...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20032

    authors: Slattery DM,Zurakowski D,Colin AA,Cleveland RH

    更新日期:2004-07-01 00:00:00

  • Determinants of chronic lung disease severity in the first year of life; A population based study.

    abstract:OBJECTIVES:First, create a clinical severity score for patients with chronic lung disease of infancy (CLDi) following neonatal intensive care unit (NICU) stay. Second, using California wide population-based data, identify factors associated with clinical severity of CLDi at 4-9 months corrected gestational age (CGA). ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23148

    authors: Gage S,Kan P,Oehlert J,Gould JB,Stevenson DK,Shaw GM,O'Brodovich HM

    更新日期:2015-09-01 00:00:00

  • Detection of Pseudomonas aeruginosa type III antibodies in children with tracheostomies.

    abstract::Pseudomonas aeruginosa is often cultured from the airways of children with tracheostomies. P. aeruginosa produces exotoxin A (ETA) and type III cytotoxins. This study tested the hypothesis that children with tracheostomies are colonized by P. aeruginosa that express these virulence factors and will have antibodies dir...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20194

    authors: Rao AR,Splaingard MS,Gershan WM,Havens PL,Thill A,Barbieri JT

    更新日期:2005-05-01 00:00:00

  • Dexmedetomidine for infant pulmonary function testing.

    abstract::For the last thirty years, oral chloral hydrate has been used for sedation of infants for lung function testing. Recently, however, availability of chloral hydrate became severely limited in the United States after two manufacturers discontinued manufacturing in 2012. Due to these limitations and the recent and ongoin...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23100

    authors: Callahan P,Pinto SJ,Kurland G,Cain JG,Motoyama EK,Weiner DJ

    更新日期:2015-02-01 00:00:00

  • Specific airway resistance in children: panting or tidal breathing?

    abstract:BACKGROUND:The measurement of specific airway resistance during tidal breathing (sRaw(tb)) has gained popularity in children, but methodological concerns have been raised regarding the electronic compensation for the thermal artifact. The panting method (sRaw(p)) is efficient in minimizing the latter, but may be associ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.22829

    authors: Coutier L,Varechova S,Demoulin B,Bonabel C,Roman-Amat C,Tuan TL,Ioan I,Schweitzer C,Marchal F

    更新日期:2014-03-01 00:00:00