Abstract：
:Functionalized neurotube are a third-generation of conduits with chemical or architectural bioactivity developed for axonal proliferation. The goal of this review is to provide a synopsis of the functionalized nerve conduits described in the literature according to their chemical and architectural properties and answer two questions: what are their mechanisms of action? Has their efficacy been proven compared to the autologous nerve graft? Our literature review relates all kind of conduits corresponding to functionalized neurotubes in peripheral nerve regeneration found in Medline and PubMed Central. Studies developing nerve gaps, chemotactic or structural features promoting each conduit, results, efficiency were selected. Fifty-five studies were selected and classified in: (a) intraluminal neurotrophic factors; (b) cell-based therapy (combined-in-vein muscles, amniotic membrane, Schwann cells, stem cells); (c) extracellular matrix proteins; (d) tissue engineering; (e) bioimplants. Functionalized neurotubes showed significantly better functional results than after end-to-end nerve suture. No studies can be able to show that neurotube results were better than autologous nerve graft results. We included all studies regardless of effectives to evaluate quality of reinnervation with modern tubulization. Functionalized neurotubes promote basic conduits for peripheral nerve regeneration. Thanks to bioengineering and microsurgery improvement, further neurotubes could promote best level of regeneration and functional recovery to successfully bridge a critical nerve gap.
journal_name
Hand Surg Rehabiljournal_title
Hand surgery & rehabilitationauthors
Regas I,Loisel F,Haight H,Menu G,Obert L,Pluvy Idoi
10.1016/j.hansur.2020.05.007subject
Has Abstractpub_date
2020-10-01 00:00:00pages
343-351issue
5eissn
2468-1229issn
2468-1210pii
S2468-1229(20)30113-4journal_volume
39pub_type
杂志文章abstract：:The use of a "bank finger" by its very nature is almost exclusively reserved for the management of traumatic hand injuries. Here, we described one case of thumb reconstruction using the patient's index finger as a "bank finger" after the excision of a grade II malignant fibrous histiocytoma. ...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2015.12.006
更新日期：2016-04-01 00:00:00
abstract：:Most extra-articular fractures of the proximal phalanges (P1) of the triphalangeal fingers can be treated conservatively with good results. Prerequisites for successful fracture treatment are intact soft tissue without any lesions of the extensor hood and stable initial fracture reduction. The key to functional conser...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2018.01.003
更新日期：2018-04-01 00:00:00
abstract：:Distal radioulnar joint (DRUJ) instabilities are common and often combined with other injuries of the interosseous membrane and/or the proximal radioulnar joint. Once they are diagnosed and the treatment is chosen, physiotherapists have limited choices due to the lack of validated protocols. The benefits of propriocep...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章,评审
doi：10.1016/j.hansur.2017.02.005
更新日期：2017-10-01 00:00:00
abstract：:The purpose of the study was to evaluate the reliability of the dorsal tangential view (DTV) of the wrist using direct visualization of the extensor compartments in vivo. Twelve patients with extensor tendon complications [nine patients with extensor synovitis, two patients with isolated extensor pollicis longus (EPL)...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2017.11.002
更新日期：2018-02-01 00:00:00
abstract：:This case series determines the clinical outcomes of relative motion extensor splints (RMES) in extensor mechanism repairs. Nine patients who underwent extensor tendon repair, juncturae tendinum or sagittal band repair were included. A forearm-based volar blocking wrist splint was applied after surgery. The RMES was c...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.10.009
更新日期：2021-02-01 00:00:00
abstract：:Osteoarthritis of the first carpometacarpal joint (CMCJ1) is a common, painful condition with positive radiological findings in up to 32% of people over 50 years of age and up to 91% of people over 80 years of age. Currently, there is insufficient evidence to recommend one surgical treatment option over the others. We...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2017.10.235
更新日期：2018-02-01 00:00:00
abstract：:Intramuscular hemangiomas are benign vascular tumors. They develop in striated muscles. Various sites have been reported in the literature but only rarely in the hand. We report on a case of an intramuscular hemangioma located within the hypothenar eminence, diagnosed by a biopsy. Treatment options are limited in the ...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2017.09.001
更新日期：2017-12-01 00:00:00
abstract：:Dorsal fracture-dislocations of the proximal interphalangeal (PIP) joint of the long fingers are in most cases unstable. They require surgery, whose primary aim is to restore and maintain articular congruency. While numerous techniques exist to treat these injuries, none have been shown to be superior to any of the ot...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2018.01.005
更新日期：2018-06-01 00:00:00
abstract：:Every doctor can be confronted, during his career, with patients presenting symptoms they created themselves. Because it is easily accessible, the hand is a favored target organ for these self-inflicted injuries. The diagnosis of factitious disorder of the hand is very difficult, rarely suggested and widely under-esti...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2017.10.237
更新日期：2018-04-01 00:00:00
abstract：:Hand preference for perineal hygiene is not a commonly recorded data unlike hand dominance. Ability to reach the perineum is essential for a good functional outcome. There is no evidence in orthopaedic literature regarding its variability. The aim of this study was to examine hand preference for perineal hygiene in a ...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章,多中心研究
doi：10.1016/j.hansur.2018.08.001
更新日期：2018-12-01 00:00:00
abstract：:The aim of the study was to assess the natural history of untreated flexor pollicis longus (FPL) tendon rupture in patients with rheumatoid arthritis (RA). We reviewed a cohort of patients to assess the long-term effect of conservative management. We reviewed nine of 11 consecutive patients. We assessed objective outc...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.08.002
更新日期：2020-12-01 00:00:00
abstract：:The aim of this study was to characterize the change in health-related quality of life following carpal tunnel decompression. Pre- and postoperative Euroqol 5 Dimensions scores were collected prospectively over three years. Outcomes were available for 435 of 563 patients (77%); mean age was 62 years. Comorbid status w...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.12.003
更新日期：2020-12-16 00:00:00
abstract：:We sought to investigate the reliability, validity, responsiveness, and interpretability of the German version of the Unité Rhumatologique des Affections de la Main (URAM) scale in patients with Dupuytren's disease. Patients with Dupuytren's disease were evaluated before receiving an injection of collagenase Clostridi...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.05.008
更新日期：2020-12-01 00:00:00
abstract：:We examined the anatomical and clinical results of a new wrist subphyseal arthrodesis method called chondrodesis, which relies on resorbable suture-bone fixation for children with severe paralytic hand deformities and does not require fixation devices or bone grafting. Four children's wrists underwent the procedure, r...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.02.007
更新日期：2020-09-01 00:00:00
abstract：:The Allieu classification takes into consideration the distal and proximal joints of the trapezium. Trapeziometacarpal (TMC) joint arthritis, TMC joint instability (TMI) and scapho-trapezio-trapezoid (STT) joint arthritis are considered independently, which better corresponds to the anatomical examinations. The aim of...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2017.06.008
更新日期：2017-10-01 00:00:00
abstract：:Some very poor results after carpal tunnel syndrome (CTS) surgery are difficult to explain. The main hypothesis of this study was that a relationship exists between self-efficiency toward pain and the difference between pre-operative and post-operative pain. The secondary hypothesis was that a relationship exists betw...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2016.08.008
更新日期：2016-12-01 00:00:00
abstract：:Surgical denervation of the thumb carpometacarpal (CMC) joint is a theoretical surgical option for thumb CMC arthritis. Some authors have described the nerve branches of thumb CMC joint. We present the innervation of the thumb CMC joint (thenar - recurrent - branch of median nerve, palmar branch of median nerve, super...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.09.011
更新日期：2021-01-16 00:00:00
abstract：:The goal of wrist denervation is to decrease pain at the wrist, whether caused by an intra- or extra-articular problem or even when the reason for the pain is unknown. It is an alternative to partial or total arthrodesis and proximal row carpectomy. Our hypothesis was that wrist denervation with a two-incision techniq...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2017.04.003
更新日期：2017-09-01 00:00:00
abstract：:This article aims to provide hand surgeons with current knowledge on the developmental biology of the upper limb. It will review positioning, limb bud emergence and formation of the apical ectodermal ridge. The development of the limb bud is analyzed in its three axes: proximal-distal, anteroposterior and dorsoventral...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章,评审
doi：10.1016/j.hansur.2018.03.007
更新日期：2018-10-01 00:00:00
abstract：:This is a review of the various approaches that can be used for open reduction and internal fixation (ORIF) of distal radius fractures. The main dissection steps are exposed and the specific indications for each approach are described. The anterior approach is discussed extensively as it is now the gold standard for O...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章,评审
doi：10.1016/j.hansur.2016.03.007
更新日期：2016-12-01 00:00:00
abstract：:Damage to the hand in patients suffering from gout is rare and is often detected at an advanced stage. The main clinical manifestations are the appearance of subcutaneous tophi at the finger joints. Other clinical manifestations of osteoarticular, tendinous or neurological lesions have been described in the hand and a...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2018.02.005
更新日期：2018-05-17 00:00:00
abstract：:The authors describe their experience using silicone infusion tubing in place of Hunter rods for two-stage zone 2 flexor tendon reconstruction in a resource-limited surgical environment. This case report features a 47-year-old, right-handed man who had no active PIP and DIP joint flexion in four fingers of the right h...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2017.06.004
更新日期：2017-10-01 00:00:00
abstract：:Exertional compartment syndrome of the forearm is a rare pathology, occurring almost exclusively in motorcycle racers. The results of endoscopic techniques are similar to those of open fasciotomies, but they are less invasive and leave smaller scars. The aim of our study was to present a new endoscopic technique for s...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.01.011
更新日期：2020-05-01 00:00:00
abstract：:Gunshot wounds to the hand often produce complex injuries and large segmental bone defects. Bone reconstruction remains a challenge in this context. The induced membrane technique is a simple and effective procedure for reconstruction of segmental bone defects. The technique is straightforward but must be performed ri...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2019.01.002
更新日期：2019-04-01 00:00:00
abstract：:The aim of this study was to assess the value of using a Canaletto® implant in combination with a gel composed of carboxymethylcellulose and polyethylene oxide in the surgical treatment of recurrent carpal tunnel syndrome (CTS). The case series included 31 patients with 32 hands operated for the second time for recurr...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.10.005
更新日期：2021-02-01 00:00:00
abstract：:Total trapeziometacarpal (TMC) joint replacement is increasingly being performed for the treatment of basal joint arthritis. However, complications such as instability or loosening are also frequent with TMC ball-and-socket joint replacement. Management of these complications lacks consensus. The purpose of this study...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2015.09.002
更新日期：2016-02-01 00:00:00
abstract：:The aim of this retrospective study was to analyze the medium-term results of patients treated with a pyrocarbon interposition implant (Pyrocardan®, Wright Medical™) after failed trapeziectomy. Eight female patients with an average age of 63 years were included in this single-center study. The average follow-up was 54...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.09.005
更新日期：2021-02-01 00:00:00
abstract：:Wrapping microsurgical sutures with a vein conduit is a well-described procedure for microsurgical nerve repair. While this has rarely been described in the context of vascular repair, this technique could increase the permeability of the sutured vessels. As part of a University Diploma in Microsurgery, 9 junior surge...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2020.04.009
更新日期：2020-10-01 00:00:00
abstract：:A case of an isolated volar dislocation of the second and third carpometacarpal (CMC) joints in an 18-year-old man is described. He presented following a game of rugby unable to move his hand or wrist. He was managed by manipulation and K-Wire fixation. Hand function was excellent following wire removal and mobilizati...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2018.06.004
更新日期：2018-10-01 00:00:00
abstract：:Several techniques have been described for fusion of the distal interphalangeal joint. The intramedullary Lync® implant (Novastep™) may be superior to other options as it is available in straight or bent configurations, does not need to be removed and does not require fingertip incisions. The objective of our prospect...
journal_title：Hand surgery & rehabilitation
pub_type： 杂志文章
doi：10.1016/j.hansur.2019.01.004
更新日期：2019-04-01 00:00:00
