Abstract:
BACKGROUND:Food allergy is common in children with prevalence up to 10%. We assessed the clinico-laboratory characteristics and frequency of food sensitization to the commonly consumed food among upper Egyptian preschool children with recurrent wheezy chest. METHODS:This cross-sectional descriptive study was conducted on 100 preschool children with recurrent wheezy chest recruited from Emergency, Allergy, and Pulmonology units, Assiut University Children's Hospital, Egypt. All enrolled patients were subjected to history taking, through examination, chest X-ray, skin prick testing (SPT), and lab investigations. RESULTS:Family history of allergy was found in 66 patients, while history of other allergies was reported in 47 patients. History of food allergy was positive in 47% of the studied patients, and 28 patients had positive reaction by SPT. Sensitization to fish, milk, egg, and wheat was found in 15, 8, 5, and 4 patients, respectively. Eighteen out of the 28 patients who were sensitized by SPT gave positive history of food allergy, while ten patients had no suggestive history; also, history suggestive of food allergy was negative in 35.7% of sensitized patients versus 61.1% of non-sensitized patients. CONCLUSIONS:Food sensitization is common in preschool Egyptian children with recurrent wheezing. IMPACT:Food sensitization is common in children with prevalence up to 10%, and in atopic children up to 30%. Sensitization to fish was the most common type of sensitization observed among preschool children with recurrent wheezing, followed by milk, eggs, and wheat, respectively. SPT aided by history is a good screening tool to determine whether patients need to avoid some foods that can cause allergy in order to help in controlling their symptoms.
journal_name
Pediatr Resjournal_title
Pediatric researchauthors
Abdallah AM,Osman NS,Mohammad HA,Metwalley KA,Embaby M,ElMelegy TTdoi
10.1038/s41390-020-0960-0subject
Has Abstractpub_date
2020-10-01 00:00:00pages
580-586issue
4eissn
0031-3998issn
1530-0447pii
10.1038/s41390-020-0960-0journal_volume
88pub_type
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journal_title:Pediatric research
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abstract::Microangiopathy, one of the most important complications of diabetes mellitus in humans, is associated with increased angiogenic response and proliferative lesions in various organs. Angiogenin, a polypeptide with a molecular size of 14 kD, is a potent inducer of vascular growth. This study aimed at investigating whet...
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journal_title:Pediatric research
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journal_title:Pediatric research
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journal_title:Pediatric research
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pub_type: 评论,杂志文章
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journal_title:Pediatric research
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Pediatric research
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更新日期:1991-08-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-200102000-00008
更新日期:2001-02-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00