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Monitoring PDT effects in basal cell carcinoma treatment using thermal imaging.

Abstract：

BACKGROUND:One of the most frequent type of malignant skin lesion (almost 95 percent of all skin tumours) is basal cell carcinoma (BCC). It is often treated by radiotherapy using ionizing radiation as well by photodynamic therapy (PDT) which is a selective method directed only on cancer cells and well tolerated by patients. MATERIALS AND METHODS:Eight male patients of the Department and Clinic of Internal Diseases, Angiology and Physical Medicine in Bytom, Medical University of Silesia, in Katowice, Poland suffering from basal cell carcinoma were monitored by thermovision during the photodynamic therapy. All lesions were diagnosed as superficial were confirmed by histopathological examination. RESULTS:The dynamics of changes observed in the isotherm area during the therapy can provide physicians with additional information. The significant increase of observed isotherm area in comparison to the lesion area diagnosed by a physician was confirmed, which may be connected with the increased metabolism processes occurring in the tissue surrounded the lesion. CONCLUSION:The obtained results based on the temperature gradient changes in the lesion vicinity area may bring some new information describing the range of biochemical and physiological processes occurring during photodynamic therapy.

journal_name

Photodiagnosis Photodyn Ther

journal_title

Photodiagnosis and photodynamic therapy

authors

Kapek Ł,Cholewka A,Szurko A,Sieroń K,Sieroń A,Kwiatek S,Stanek A

doi

10.1016/j.pdpdt.2020.101845

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

101845

eissn

1572-1000

issn

1873-1597

pii

S1572-1000(20)30199-X

journal_volume

31

pub_type

杂志文章

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