Abstract:
OBJECTIVES:Families are a transmission route for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) because of the close contact. Monitoring of the viral load will be a valuable method to reduce the optimal number of quarantine days, especially in presymptomatic and symptomatic carriers of their households. The traditional three-generation families living together are seen frequently in East Asia, including in Taiwan. STUDY DESIGN:We report on a family cluster with six individuals infected with coronavirus disease in Taiwan. METHODS:The current public policy in Taiwan is quarantine for at least 14 days, based on the incubation period, or until the patient has tested negative three days in a row using the SARS-CoV-2 reverse transcription polymerase chain reaction. Details on the onset date of clinical symptoms, throat swab conversion, and course of disease were collected from medical records retrospectively. RESULTS:In the household of this three-generation Taiwanese family, the infection rate was 60%. The ratio of males to females was 4:2, and the age range was 11-85 years. The prevalence of asymptomatic disease was 33.3% (2/6). The longest throat swab conversion time was 37 days, and the estimated course of disease from symptoms to first conversion of throat swab was 59 days. CONCLUSIONS:Large families, including three-generation families in a single dwelling, should be monitored when the index case is found. Presymptomatic and symptomatic family members could be quarantined for an appropriate duration which, in our experience, is 2 months.
journal_name
Public Healthjournal_title
Public healthauthors
Yang MC,Hung PP,Wu YK,Peng MY,Chao YC,Su WLdoi
10.1016/j.puhe.2020.05.043subject
Has Abstractpub_date
2020-08-01 00:00:00pages
31-33eissn
0033-3506issn
1476-5616pii
S0033-3506(20)30205-5journal_volume
185pub_type
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