Abstract:
:One hundred and eighty patients with incident fragility hip fracture admitted to a tertiary care center in Sri Lanka were followed up for 12 months. When compared with those survived, patients who died were older and had higher comorbidity and physical impairment, before fracture and at discharge from the hospital. INTRODUCTION:This study examined the factors that are associated with mortality within the first 12 months, of patients admitted with fragility hip fracture to a tertiary care center in Southern Sri Lanka. METHODS:One hundred and eighty consecutive patients admitted with new fragility hip fracture were followed up for 12 months post-fracture. Apart from age and gender, information related to physical dependency (prefracture and at discharge) and comorbidity were collected from all subjects. RESULTS:Of 180 patients (149women), 107 had surgery while the rest were managed conservatively. Mean (SD) age of study subjects was 76.5 (9.2 years). Thirty-three patients died within the first 12 months were older and had higher comorbidity and physical impairment before fracture and at discharge from the hospital, when compared with those survived. Relative risk (95% CI, p value) of death for being a male was 6.52 (3.18-11.5, < 0.001) and corresponding values for conservative management were 6.59 (2.86-15.2, < 0.001). In the ROC analysis, in which mortality/survival was taken as state variable, AUCs for age, Charlson index, age-adjusted Charlson index, and Barthel index before fracture and Barthel index at discharge were 0.77 (0.04), 0.79 (0.04), 0.70 (0.05), 0.67 (0.05), and 0.76 (0.04 ) (p < 0.01 for all). Age-adjusted odd ratios (95% CI) of ACCI, CCI, surgical management, and Barthel index before fracture and at discharge were 2.21 (1.37 to 3.57), 2.37 (1.46 to 3.83), 0.18 (0.06 to 0.53), 0.91 (0.85 to 0.97), and 0.93 (0.88 to 0.99), respectively (p < 0.05 for all). CONCLUSIONS:We conclude that advanced age, male gender, higher comorbidity, physical impairment before and after fracture, and conservative management lead to a higher risk of mortality in patients admitted with incident fragility hip fracture. This study can be used as a platform for future research in this area in Sri Lanka.
journal_name
Arch Osteoporosjournal_title
Archives of osteoporosisauthors
Abeygunasekara T,Lekamwasam S,Alwis G,Lenora Jdoi
10.1007/s11657-020-00769-6subject
Has Abstractpub_date
2020-06-25 00:00:00pages
95issue
1eissn
1862-3522issn
1862-3514pii
10.1007/s11657-020-00769-6journal_volume
15pub_type
杂志文章abstract::We surveyed 573 physicians in the Middle East regarding osteoporosis management. Sixty percent had access to, but were not in charge of, densitometry reporting. Screening for secondary causes was common; 62% were aware of FRAX®; less than half used it. Medications were accessible, and most participants had concerns re...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0609-y
更新日期:2019-06-07 00:00:00
abstract::In the past 10 years after implementation, the orthogeriatric treatment model led in general to consistent outcomes for 1555 older adults in terms of most of the complications and mortality. Surgery was more often delayed to 24-48 h after arrival at the hospital, while the length of hospital stay shortened. INTRODUCT...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0550-5
更新日期:2018-11-19 00:00:00
abstract::We have characterised 997 hip fracture patients from a representative 45 Spanish hospitals, and followed them up prospectively for up to 4 months. Despite suboptimal surgical delays (average 59.1 hours), in-hospital mortality was lower than in Northern European cohorts. The secondary fracture prevention gap is unaccep...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0515-8
更新日期:2018-09-14 00:00:00
abstract::In November 2008, the "2nd Summit on Osteoporosis-Central and Eastern Europe (CEE)" was held in Warsaw, Poland. Discussions at this meeting focused on the identification and discussion of diagnostic, preventive, and therapeutic measures used in CEE. Evaluated information was used to identify issues regarding diagnosis...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-009-0028-6
更新日期:2009-12-01 00:00:00
abstract::If all adults with osteoporosis in the European Union (EU) and United States (US) used calcium and vitamin D supplements, it could prevent more than 500,000 fractures/year in the EU and more than 300,000/year in the US and save approximately €5.7 billion and US $3.3 billion annually. PURPOSE:Evaluate the cost-effecti...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0589-y
更新日期:2019-04-30 00:00:00
abstract::The effects of gluteal implants on bone mass remain unclear. Transgender women with ILS presented higher BMD in the hip compared with transgender women without implants, while no difference was observed in other sites. These results may be artifactual and suggest using spine/forearm sites for DXA in individuals with I...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00824-2
更新日期:2020-09-22 00:00:00
abstract:UNLABELLED:Although depression has been associated to worst bone physical properties in adulthood, this study showed that depressive symptoms were not significantly associated to bone mineral density measured at the forearm during adolescence. PURPOSE:Depressive conditions have been related to the reduction of bone mi...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-014-0173-4
更新日期:2014-01-01 00:00:00
abstract::While adherence to osteoporosis treatment is low, patients' preference for osteoporosis treatment is unknown in Chinese patients. Chinese patients are willing to receive treatments with higher clinical efficacy and lower out-of-pocket cost. In addition, annual intravenous infusion and 6-month subcutaneous injection ar...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0624-z
更新日期:2019-07-31 00:00:00
abstract::Hip fracture becomes a major public health issue with the growing aging population. This study evaluated a multidisciplinary co-management program for older hip fracture patients and found it significantly improved the best practice indicators. It provided preliminary evidence to support the use of such intervention i...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0594-1
更新日期:2019-03-22 00:00:00
abstract::The original version of this article, published on 05 August 2020, unfortunately contained a mistake. ...
journal_title:Archives of osteoporosis
pub_type: 杂志文章,已发布勘误
doi:10.1007/s11657-020-00813-5
更新日期:2020-09-08 00:00:00
abstract:UNLABELLED:It is unknown whether osteoporosis is socially patterned. Using data from the Hertfordshire Cohort Study we found no consistent evidence for social inequalities in prevalent or incident fracture, bone mineral density or loss rates, or bone strength. Public health strategies for prevention of osteoporosis sho...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-012-0069-0
更新日期:2012-01-01 00:00:00
abstract:UNLABELLED:Minimal data on bone mineral density changes are available from populations in developing countries. Using calcaneal quantitative ultrasound (QUS) techniques, the current study contributes to remedying this gap in the literature by establishing a normative data set on the indigenous Shuar and non-Shuar Colon...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-011-0056-x
更新日期:2011-01-01 00:00:00
abstract:UNLABELLED:Bone mineral density (BMD), metabolic syndrome (MS), and vitamin D levels were evaluated in 73 indigenous from south of Brazil aged between 40 and 86 years. BMD loss in lumbar spine was detected in 63 %, MS was detected in 76.7 %, and vitamin D levels were altered in 67 % of subjects. PURPOSE:This study aim...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-013-0134-3
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:Medical treatment of osteoporosis should preferably be both effective and have minimal side effects. The aim of the present study was to examine long-term benefits and risks of parathyroid hormone (PTH) treatment in compliant patients. METHODS:This is a nationwide retrospective cohort study based on national r...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0444-6
更新日期:2018-05-02 00:00:00
abstract::This study estimated the direct medical costs of osteoporotic fractures from a large claim database in Japan. We further identified several comorbidities which drove the treatment costs. The results would contribute to health economic analysis as well as understanding of individual financial burden in Japan. INTRODUC...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0456-2
更新日期:2018-04-25 00:00:00
abstract:UNLABELLED:Serum concentrations of osteocalcin (OC) decrease and those of C-terminal telopeptide of type 1 collagen (CTX) increase during weight loss in adolescent girls with eating disorders (ED). The impact of weight loss on bone metabolism markers is greatest in premenarcheal girls. INTRODUCTION:Adolescents with ED...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-012-0090-3
更新日期:2012-01-01 00:00:00
abstract::A workflow tool for measurements of vertebral heights on lateral spine radiographs based on automated placements of 6 points per vertebra was evaluated. The tool helps to standardize point placement among operators. Its success rate is very good in normal vertebrae but lower in vertebrae with more severe fractures. Ma...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0577-2
更新日期:2019-02-11 00:00:00
abstract:OBJECTIVES:Many studies have explored the association between neuropathy and osteoporosis in patients with diabetes mellitus. However, the results still remain inconsistent and controversial. We aimed to estimate the association between diabetic neuropathy and osteoporosis. METHODS:Databases, including PubMed, Embase,...
journal_title:Archives of osteoporosis
pub_type: 杂志文章,meta分析
doi:10.1007/s11657-020-00804-6
更新日期:2020-08-10 00:00:00
abstract::This study aims to determine the awareness of osteoporosis and factors that determine awareness of osteoporosis. Results showed that osteoporosis awareness was associated with age (p = 0.006) and occupation (p < 0.001) but not gender, marital status, and level of education. There is therefore need for educational inte...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-017-0342-3
更新日期:2017-12-01 00:00:00
abstract:UNLABELLED:Population ageing presents significant challenges for many developed nations. Accurately forecasting the likely future burden of age-related medical conditions, such as hip fracture, is critical. In this study, we present estimates of the current and future burden of hip fracture in NSW, Australia, providing...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-014-0200-5
更新日期:2014-01-01 00:00:00
abstract::This study aimed to investigate the correlation between bone mineral density (BMD) with hemoglobin and ferritin levels in Palestinian patients suffering from various types of hemoglobinopathies. The study revealed the thresholds of hemoglobin and ferritin to protect against low BMD in these patients. PURPOSE:Iron ove...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00853-x
更新日期:2020-11-13 00:00:00
abstract::This study assesses the impact of risk factors for fracture in women aged 80+ and 60-79. The results suggest that risk assessment which fits younger women may not be suited for the 80+ strata as many common risk factors are less predictive in the older compared to the younger cohort. PURPOSE:This study assesses wheth...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0592-3
更新日期:2019-04-08 00:00:00
abstract::Our study describes the clinical characteristics of patients with fragility fractures. It also shows there is a low knowledge about osteoporosis and its relation to fractures, in addition to the very poor adherence to medical advice and treatment. INTRODUCTION:Osteoporosis is a systemic skeletal disease associated wi...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0646-6
更新日期:2019-09-05 00:00:00
abstract::In a large population-based study of Iran, the age-standardized prevalence of osteoporosis was 24.6% in men and 62.7% in women aged ≥ 60 years. Osteoporosis was negatively associated with body mass index in both sexes, and with diabetes in men and hypertriglyceridemia in women. PURPOSE:Population aging has made osteo...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00872-8
更新日期:2021-01-21 00:00:00
abstract::Giant cell tumor (GCT) of the bone, also called osteoclastoma, is a rare complication of Paget's bone disease. We report a patient from Southern Italy who developed a GCT infiltrating the neighboring tissues. The natural history and the therapeutic outcomes of this unique complication of Paget's bone disease are prese...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-009-0027-7
更新日期:2009-12-01 00:00:00
abstract::Osteoporosis has become an important health concern even in men. We aimed to analyze its prevalence and associated factors in Korean men. Low socioeconomic status, unhealthy lifestyle, and chronic kidney disease increased the risk. High-risk men even at young age need to evaluate bone mineral density, and proper inter...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0506-9
更新日期:2018-08-20 00:00:00
abstract::This study aims to evaluate factors affecting the quality of life (QOL) of hypoparathyroidism. While QOL is reduced in post-surgical and non-surgical groups, mental health seems to be less affected in non-surgical patients. Having an additional disease affects QOL negatively but having thyroid cancer may not change th...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00759-8
更新日期:2020-05-19 00:00:00
abstract:UNLABELLED:This survey describes the epidemiology of approximately 1800 low-energy humeral fractures seen in a large emergency department in Northern Italy over 7 years (2007-2013), highlighting the differences from previous Italian studies. PURPOSE:The purpose of this study was to determine the incidence of humeral f...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-015-0228-1
更新日期:2015-01-01 00:00:00
abstract::In pre-pubertal girls, nutrient intakes and non-aquatic organized activity were evaluated as factors in vertebral body bone mass, structure, and strength. Activity, vitamin B12, and dietary fiber predicted bone outcomes most consistently. Exercise and vitamin B12 appear beneficial, whereas high fiber intake appears to...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-017-0312-9
更新日期:2017-12-01 00:00:00
abstract::To ensure meaningful results in a clinical audit, as many hospitals as possible should participate. To optimise participation, the data collection process should either be performed by additional staff or be automated. Active participation may be promoted by offering relevant external parties insight into the actual q...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0652-8
更新日期:2019-11-21 00:00:00