Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management.

Abstract:

:We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically.

journal_name

Rev Soc Bras Med Trop

authors

Santana MF,Pivoto G,Alexandre MAA,Baía-da-Silva DC,Borba MGDS,Val FA,Brito-Sousa JD,Melo GC,Monteiro WM,Souza JVB,Pinheiro SB,Ferreira LCL,Naveca FG,Nascimento VA,Corado ALG,Hajjar LA,Silva Neto JR,Siva GAV,Pasqualott

doi

10.1590/0037-8682-0401-2020

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

e20200401

eissn

0037-8682

issn

1678-9849

pii

S0037-86822020000100719

journal_volume

53

pub_type

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