Abstract:
:We cared for 124 pediatric patients with a histologic diagnosis of Langerhans' cell histiocytosis (histiocytosis X) over a period of 14 years. Clinical, laboratory, and radiographic findings were analyzed. The most frequent manifestations were bone lesions, lymph node involvement, and skin infiltration. Liver disease was noted in 50% of patients and lung disease in 23%; hematologic changes were also frequent. Dysfunction and involvement of these three organ systems, plus age of onset, distinguished the group of patients with the highest mortality. All patients with generalized disease or organ dysfunction were treated with systemic chemotherapy. The actuarial survival curve at 10 years was 63%.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Rivera-Luna R,Martinez-Guerra G,Altamirano-Alvarez E,Martinez-Avalos A,Cardenas-Cardoz R,Ayon-Cardenas A,Ruiz-Maldonado R,Lopez-Corella Edoi
10.1111/j.1525-1470.1988.tb01160.xsubject
Has Abstractpub_date
1988-08-01 00:00:00pages
145-50issue
3eissn
0736-8046issn
1525-1470journal_volume
5pub_type
杂志文章abstract:BACKGROUND:Acrodermatitis acidemica is a recently proposed term for the rash that is similar to acrodermatitis enteropathica, which is encountered in organic acidemias. However, acrodermatitis enteropathica-like eruption may be seen in metabolic disorders other than organic acidemias. OBJECTIVE:The aim of this study w...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2008.00803.x
更新日期:2009-03-01 00:00:00
abstract::Chinese cloth diapers differ from disposable diapers in several respects that are central to our understanding of the etiology of diaper dermatitis (DD), yet there are no published reports on the dermatological correlates of this manner of infant care, which is prevalent among the world's second-largest pediatric popu...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2011.01494.x
更新日期:2011-07-01 00:00:00
abstract::Scar formation is a physiologic reaction to dermal injury. We describe a 11-year-old girl and her 15-year-old cousin, who both presented with stellate scarlike lesions primarily located on the hands. Histopathologic examination confirmed scar tissue formation. There was no history of initiating trauma or other possibl...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2008.00644.x
更新日期:2008-03-01 00:00:00
abstract::Allergic contact dermatitis reaction to topical "black henna" tattoo is usually described secondary to the organic dye para-phenylenediamine, a derivative of analine. Allergic contact dermatitis reactions to para-phenylenediamine are well recognized and most commonly involve an eczematous reaction that may become gene...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2008.00634.x
更新日期:2008-03-01 00:00:00
abstract::Henoch-Schönlein purpura is an acute leukocytoclastic vasculitis that primarily affects children. Henoch-Schönlein purpura is often associated with an infection, and a wide variety of infectious agents have been implicated in the pathogenesis. We report a child with Henoch-Schönlein purpura associated with Helicobacte...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2008.00786.x
更新日期:2008-11-01 00:00:00
abstract::Graft-versus-host disease (GVHD) is an underappreciated complication of autologous hematopoietic stem cell transplantation (AHSCT) that can affect the skin, gastrointestinal tract, and liver. The development of this rare condition is probably due to an impairment of immunologic tolerance that can occur spontaneously t...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/pde.12407
更新日期:2015-03-01 00:00:00
abstract::We evaluated two patients with hereditary bullous poikiloderma. Both had acral bullae, generalized poikiloderma with prominent atrophy, and acral keratoses. One patient, with sporadic disease, had, in addition, urethral and subglottic stenoses, webbing of digits, and poor dentition. The other patient, whose disease wa...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1525-1470.1989.tb01004.x
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Previous studies have demonstrated an increased prevalence of inflammatory bowel disease (IBD) in adults with hidradenitis suppurativa (HS). Whether the same association exists in pediatric patients is unknown. Fecal calprotectin (FC) is used to screen and monitor disease activity in IBD. There ar...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14417
更新日期:2020-10-25 00:00:00
abstract::Menkes's syndrome (trichopoliodystrophy) is an x-linked, recessive genodermatosis characterized by hair defects, severe retardation, convulsions, progressive neurologic deterioration, and early death. Recent studies in copper metabolism suggest that Menkes's syndrome may be a storage disease in which copper is irrever...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1984.tb01135.x
更新日期:1984-04-01 00:00:00
abstract::Stevens-Johnson syndrome is a potentially fatal condition that manifests mainly on the skin and mucosal surfaces but also affects other vital organs. There are no report of Stevens-Johnson syndrome caused by brucella infection in the literature. In this article, a previously healthy boy, diagnosed as Stevens-Johnson s...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2007.00472.x
更新日期:2007-07-01 00:00:00
abstract::Demand for pediatric dermatologic care far exceeds the supply of pediatric dermatologists. Teledermatology has been proposed as a solution to improve access to care, however, data regarding teledermatology use for pediatric patients are lacking. Surveys assessing use and experience with teledermatology were administer...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2008.00624.x
更新日期:2008-03-01 00:00:00
abstract::Erythema nodosum (EN) in association with kerion celsi is a rare condition in children, with only 11 cases having been reported in the English literature. We describe a new case in a 7-year-old boy in whom the disorder had begun 2 months before. He had many inflamed, boggy, suppurative nodules over the left occipitopa...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1525-1470.2011.01523.x
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Atypical and severe clinical manifestations of primary and recurrent herpes simplex virus (HSV) infections may present to a pediatric dermatologist for evaluation. The purpose of this study was to characterize the clinical features of the population diagnosed with HSV referred to a pediatric derma...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13190
更新日期:2017-07-01 00:00:00
abstract::Granular parakeratosis has only recently been described and typically occurs in adults. We report the first instance of this condition affecting a child. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1046/j.1525-1470.2002.00044.x
更新日期:2002-03-01 00:00:00
abstract::Granular cell tumors are uncommon in the vulva. We cared for a child who had a solitary vulvar tumor since infancy. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1993.tb00044.x
更新日期:1993-06-01 00:00:00
abstract::Acne mechanica is defined as being any acneiform eruption in areas of friction, pressure, stretching, rubbing, pinching, or occlusion of the skin in any individual, regardless of preexisting acne. Various causes have been reported, including prolonged back rest against a chair or bed, occlusive clothing, pressure from...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13817
更新日期:2019-07-01 00:00:00
abstract::We describe a bullous-hemorrhagic reaction of the ear lobes in a child with nephrosis after levamisole intake. This drug is used in children as an alternative treatment of corticosteroid-responsive nephrotic syndrome. Histologic evaluation of a lesion revealed necrotizing vasculitis involving mainly the large vessels ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1997.tb00695.x
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:Fibroblastic connective tissue nevi (FCTN) are benign skin conditions characterized by bland spindle cells infiltrating the reticular dermis and the upper subcutis with preservation of adnexal structures. A subset of FCTN expresses CD34, which may cause difficulties in the differential diagnosis, in particul...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13571
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Psoriasis is a chronic, immune-mediated dermatologic disorder with a prevalence among children estimated at 0.1%-0.45%, and a median age of onset at approximately 7-10 years. Pediatric psoriasis is known to have negative impacts on health-related quality of life. Among the most bothersome symptoms...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14403
更新日期:2020-12-18 00:00:00
abstract::Hemangiomas are classified as focal or segmental according to the morphology and distribution of lesions. Congestive cardiac failure is frequently encountered in diffuse hepatic hemangiomas due to high-volume shunting and rarely in hemangiomas confined to the skin. We report here the case of a large multifocal hemangi...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12476
更新日期:2015-01-01 00:00:00
abstract::Pyoderma gangrenosum (PG) is an inflammatory neutrophilic dermatosis that may present with limited to severe disease, posing a therapeutic challenge. A 7-year-old African female who presented with extensive PG showed a remarkable response to corticosteroid wrap monotherapy. ...
journal_title:Pediatric dermatology
pub_type:
doi:10.1111/pde.14348
更新日期:2020-09-06 00:00:00
abstract::Verrucous perforating collagenoma is an extremely rare variant of acquired perforating dermatosis that has been seldom described in literature. We present the case of an 18-month-old boy who presented with an erythematous plaque with a central keratotic plug on the leg. Histopathology revealed transepidermal eliminati...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13887
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Understanding the importance of the barrier function of the skin of preterm and term neonates is crucial in effective neonatal skin and diaper care. This literature search aimed to review the development of different practices in neonatal care to maintain skin barrier function, in turn preventing diaper derm...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/pde.13714
更新日期:2019-01-01 00:00:00
abstract::Halo dermatitis is a pruritic, eczematous eruption on pigmented nevi and halo nevi in young adults. It may be mistaken for nummular eczema, psoriasis, or fungal skin infection. Awareness of halo dermatitis will possibly reveal more cases in children, which have been reported only rarely. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1992.tb00347.x
更新日期:1992-09-01 00:00:00
abstract::Two hundred and sixty-eight children with pediculosis capitis took part in a comparative study to test the efficacy of five different pediculocides commonly used in Israel. The preparations used were pyrethrin shampoo, pyrethroid spray, malathion solution, carbaryl shampoo and carbaryl lotion. Carbaryl lotion and mala...
journal_title:Pediatric dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1525-1470.1988.tb00903.x
更新日期:1988-11-01 00:00:00
abstract::Four unrelated children with osteoma cutis and Albright hereditary osteodystrophy (pseudohypoparathyroidism and pseudopseudohypoparathyroidism) are described. All four patients were normocalcemic when they were first seen with cutaneous ossification. A diagnosis of Albright hereditary osteodystrophy was established on...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1992.tb00318.x
更新日期:1992-03-01 00:00:00
abstract::We report an unusual congenital vesiculopustular eruption arising in a neonate as the result of the transient myeloproliferative disorder (TMD) associated with trisomy 21. In this instance, the neonate was phenotypically normal, making the diagnosis more elusive. Initially the lesions were clinically suspicious for he...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.0736-8046.2004.21505.x
更新日期:2004-09-01 00:00:00
abstract::Papular epidermal nevus with "skyline" basal cell layer (PENS), a variant of epidermal nevus, was recently described in otherwise normal children. We describe herein a patient with multiple, typical PENS lesions associated with peculiar facies, bilateral Achilles tendon shortening, and mild psychomotor delay. The asso...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2012.01830.x
更新日期:2013-07-01 00:00:00
abstract::A research task force of the Society for Pediatric Dermatology (SPD) was established to investigate the barriers to expanding research in the field of pediatric dermatology. A survey was designed to address constraints limiting research activities among members of the SPD. A nine-question survey was distributed to SPD...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2010.01162.x
更新日期:2010-07-01 00:00:00
abstract::Triethanolamine is used as an emulsifier in many cosmetics and in topical medications, yet the occurrence of contact dermatitis to cosmetics containing triethanolamine is rare in childhood. Our case highlights how young age should not be a deterrent to investigation and demonstrates the importance of patch testing wit...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12537
更新日期:2015-05-01 00:00:00