Anticonvulsant properties of Euterpe oleracea in mice.

abstract：:The system of GABA transporters in neural cells constitutes an efficient mechanism for terminating inhibitory GABAergic neurotransmission. As such these transporter are important therapeutical targets in epilepsy and potentially other neurological diseases related to the GABA system. In this study a number of analogs ...

journal_title：Neurochemistry international

authors： Sarup A,Larsson OM,Bolvig T,Frølund B,Krogsgaard-Larsen P,Schousboe A

更新日期：2003-09-01 00:00:00

abstract：:The possible influence of cholinergic and dopaminergic mechanisms on neurotensin-containing neurones was examined at two different levels; nucleus accumbens and striatum in the rat brain. The acute treatment with the anticholinergic drugs atropine and scopolamine increased neurotensin concentrations in the striatum an...

journal_title：Neurochemistry international

authors： Frey P,Lis M,Coward DM

更新日期：1988-01-01 00:00:00

abstract：:Rapid administration of large doses of ammonia leads to death of animals, which is largely prevented by pretreatment with N-methyl-D-aspartate (NMDA) receptor antagonists. The present study focuses on a subunit(s) of NMDA receptor involved in ammonia-induced death by use of NMDA receptor GluRepsilon subunit-deficient ...

journal_title：Neurochemistry international

authors： Kitano T,Matsumura S,Seki T,Hikida T,Sakimura K,Nagano T,Mishina M,Nakanishi S,Ito S

更新日期：2004-01-01 00:00:00

abstract：:Long-term potentiation (LTP), a model of activity-dependent synaptic plasticity and of certain forms of memory, comprises the persistent enhancement of excitatory neurotransmission that results from high-frequency activation. A presynaptic component of LTP is thought to be modulated by a retrograde messenger generated...

journal_title：Neurochemistry international

authors： Bazan NG,Packard MG,Teather L,Allan G

更新日期：1997-02-01 00:00:00

abstract：:One hour of ischemia significantly increased protein S100B release from rat brain slices without altering lactate dehydrogenase leakage. Reoxygenation of the ischemic slices, however, increased the levels of these biochemical markers in the medium. Although removal of extracellular Ca(+2) ions from the medium did not ...

journal_title：Neurochemistry international

authors： Büyükuysal RL

更新日期：2005-12-01 00:00:00

abstract：:Parkinson's disease (PD) is the second most common neurodegenerative disorder mostly affecting the aging population over sixty. Cardinal symptoms including, tremors, muscle rigidity, drooping posture, drooling, walking difficulty, and autonomic symptoms appear when a significant number of nigrostriatal dopaminergic ne...

journal_title：Neurochemistry international

authors： Sharma S,Moon CS,Khogali A,Haidous A,Chabenne A,Ojo C,Jelebinkov M,Kurdi Y,Ebadi M

更新日期：2013-09-01 00:00:00

abstract：:Human atrial natriuretic peptide (Ser 99-Tyr 126) was rapidly degraded by both choroid plexus and hypothalamic membranes with a complex pattern of cleavage. The use of protease inhibitors allowed a preliminary characterization of the enzymes involved in the hydrolysis of the Ser-Phe and Phe-Arg bonds of iodine-labelle...

journal_title：Neurochemistry international

authors： Deschodt-Lanckman M,Vanneste Y,Michaux F

更新日期：1988-01-01 00:00:00

abstract：:Stroke causes neuronal cell death and destruction of neuronal circuits in the brain and spinal cord. Injury to the brain tissue induces sterile inflammation triggered by the extracellular release of endogenous molecules, but cerebral inflammation after stroke is gradually resolved within several days. In this pro-reso...

journal_title：Neurochemistry international

authors： Sakai S,Shichita T

更新日期：2019-11-01 00:00:00

abstract：:Thyrotropin releasing hormone (TRH) present in several brain areas has been proposed as a neuromodulator. Its administration produces opposite effects to those observed with acute ethanol consumption. Opioid peptides, in contrast, have been proposed to mediate some of the effects of alcohol intoxication. We measured T...

journal_title：Neurochemistry international

authors： de Gortari P,Méndez M,Rodríguez-Keller I,Pérez-Martínez L,Joseph-Bravob P

更新日期：2000-11-01 00:00:00

abstract：:Development of tissue structure and three-dimensional microenvironment is crucial for regeneration of axons in the peripheral nerve repair. In this study we aimed to evaluate the efficacy of nerve regeneration by using an acellular nerve allograft (ANA) injected with allogenic skin-derived precursor differentiated Sch...

journal_title：Neurochemistry international

authors： Wang H,Wu J,Zhang X,Ding L,Zeng Q

更新日期：2016-07-01 00:00:00

abstract：:A protein, designated as protein 10 (MW = 29 kDa, pI = 5.3), was shown to be highly localized to the cochlear nuclei of guinea-pigs and rats by the use of two-dimensional gel electrophoresis. In gels from guinea-pig brain, this protein appeared greatest in amounts in the ventral cochlear nucleus and within the deep re...

journal_title：Neurochemistry international

authors： Winsky L,Nakata H,Jacobowitz DM

更新日期：1989-01-01 00:00:00

abstract：:Using specific antibodies to met-enkephalin, met-enkephalin-Arg(6)-Phe(7) and met-enkephalin-Arg(6)-Gly(7)-Leu(8), we have studied the distribution of these opioid peptides in the frog adrenal gland by means of the indirect immunofluorescence technique. Bright staining of all chromaffin cells was observed by applicati...

journal_title：Neurochemistry international

authors： Leboulenger F,Cupo A,Castanas E,Benyamina M,Pelletier G,Vaudry H

更新日期：1986-01-01 00:00:00

abstract：:Oxidatively damaged proteins and lipid peroxidation products have been shown to accumulate in the brain of neurodegenerative diseases, such as Alzheimer's disease and multiple sclerosis, and oxidized lipoprotein is considered to be toxic and neurodegenerative. However, the role of lipoprotein and its oxidized form in ...

journal_title：Neurochemistry international

authors： Sato K,Tobo M,Mogi C,Murata N,Kotake M,Kuwabara A,Im DS,Okajima F

更新日期：2014-03-01 00:00:00

abstract：:The phosphorylation of proteins on tyrosine residues, initially believed to be primarily involved in cell growth and differentiation, is now recognized as having a critical role in regulating the function of mature cells. The brain exhibits one of the highest levels of tyrosine kinase activity in the adult animal and ...

journal_title：Neurochemistry international

authors： Gurd JW

更新日期：1997-11-01 00:00:00

abstract：:Prenatal exposure to diazepam (DZ), a positive allosteric modulator of the gamma-aminobutyric acid(A) (GABA(A)) receptor complex, exerts profound effects that become more evident during puberty and in many cases are sex-specific, suggesting that such exposure interferes with the activity of steroid hormones. Apart fro...

journal_title：Neurochemistry international

authors： Cannizzaro C,D'Amico M,Altobelli D,Preziosi P,Martire M

更新日期：2003-07-01 00:00:00

abstract：:Age is the leading risk factor for many of the most prevalent and devastating diseases including neurodegenerative diseases. A number of herbal medicines have been used for centuries to ameliorate the deleterious effects of ageing-related diseases and increase longevity. Oxidative stress is believed to play a role in ...

journal_title：Neurochemistry international

authors： Steele ML,Truong J,Govindaraghavan S,Ooi L,Sucher NJ,Münch G

更新日期：2013-04-01 00:00:00

abstract：:The present study was designed to investigate the turnover rates of D1 dopamine receptors in the brain and retina of adult and aged rats. To this aim, we monitored the increase in the density of 3H-SCH 23390 binding sites after the administration of the irreversible antagonist N-ethoxycarbonyl-2-ethoxy-1,2 dihydroquin...

journal_title：Neurochemistry international

authors： Giorgi O,Pibiri MG,Dal Toso R,Toffano G,Biggio G

更新日期：1992-03-01 00:00:00

abstract：:The sensitivity of [(3)H]GABA and [(3)H]muscimol high-affinity binding sites to physiological (Krebs-Ringer's bicarbonate) and non-physiological (Tris-citrate) buffers was examined using synaptosomal membranes from bovine retinas. The maximum number of sites (B(max)) for [(3)H]GABA was present when the tissue was assa...

journal_title：Neurochemistry international

authors： Madtes P Jr,Bashir-Elahi R,Chader GJ

更新日期：1986-01-01 00:00:00

abstract：:It was previously reported that the K+-evoked release of somatostatin-like immunoreactivity (SRIF-LI) and of cholecystokinin-like immunoreactivity (CCK-LI) from superfused rat cerebrocortical synaptosomes can be enhanced by NMDA or D-serine alone. We here studied the effects of extraterminal pH changes on SRIF-LI and ...

journal_title：Neurochemistry international

authors： Gemignani A,Paudice P,Longordo F,Raiteri M

更新日期：2004-10-01 00:00:00

abstract：:A simple, rapid and sensitive method for the detection of acetylcholine and choline in tissue extracts is reported. Acetylcholine and choline are first separated by HPLC then react in a mini-column with acetylcholinesterase and choline oxidase immobilized on Sepharose. The resulting H(2)O(2) produced by choline oxidas...

journal_title：Neurochemistry international

authors： Stadler H,Nesselhut T

更新日期：1986-01-01 00:00:00

abstract：:Previously we reported that gene expression of astrocytic 5-HT2B receptors was decreased in brains of depressed animals exposed to chronic mild stress (CMS) (Li et al., 2012) and of Parkinson's disease (Song et al., 2018). Depression is also one of the psychiatric symptoms in hyperammonemia, and astrocyte is a primary...

journal_title：Neurochemistry international

authors： Yue T,Li B,Gu L,Huang J,Verkhratsky A,Peng L

更新日期：2019-10-01 00:00:00

abstract：:In order to elucidate the effects of MPTP on enkephalinergic neurons, dopamine (DA), norepinephrine (NE), proenkephalin (PE) mRNA and met-enkephalin (ME) were measured in striatum, olfactory tubercle, and prefrontal cortex of C57/B16 mice 1 day-2 weeks following treatment with 96 mg/kg MPTP HCl (24 mg/kg i.p., twice/d...

journal_title：Neurochemistry international

authors： Mitsuo K,Cosi C,Harvey-White JD,Schwartz JP

更新日期：1993-02-01 00:00:00

abstract：:Cholinergic neuroblastoma NS20Y cells were differentiated by the chicken gizzard extract. They were first inoculated into a glass culture bottle and the aggregated cells which grew in the suspension culture were collected. The aggregated cells (round and immature neuroblastoma cells) were seeded on a polyornithinecoat...

journal_title：Neurochemistry international

authors： Miki N,Higashida H,Hayashi Y,Akiyama M,Kuo CH

更新日期：1982-01-01 00:00:00

abstract：:Depression is highly comorbid with anxiety disorders and associated with profound cognitive impairment. Moreover, cognitive deficits associated with hippocampal dysfunction are central in depression and anxiety disorders. Furthermore, depression is accompanied by glutamatergic dysfunction which can further impair the ...

journal_title：Neurochemistry international

authors： Chakraborty S,Tripathi SJ,Srikumar BN,Raju TR,Shankaranarayana Rao BS

更新日期：2020-01-01 00:00:00

abstract：:D-aspartate is present in significant concentrations throughout the nervous tissue but its physiological role is still under discussion. Here, we report the process of d-aspartate release in retinal cells. [(3)H]-d-aspartate release occurs through a glutamate/aspartate exchange mechanism using excitatory amino acid tr...

journal_title：Neurochemistry international

authors： Stutz B,Yamasaki EN,de Mello MC,de Mello FG

更新日期：2011-06-01 00:00:00

abstract：:The aim of the present study was to investigate, whether dopamine D1 and/or D2 receptors are able to interfere with the ATP-induced increase of the intracellular Ca2+ concentration ([Ca2+]i) in cultured striatal neurons identified by their morphological characteristics and their [Ca2+]i transients in response to a hig...

journal_title：Neurochemistry international

authors： Rubini P,Engelhardt J,Wirkner K,Illes P

更新日期：2008-01-01 00:00:00

abstract：:Iron accumulation is considered to be involved in the pathogenesis of Parkinson's disease. To demonstrate the relationship between peripheral iron overload and dopaminergic neuron loss in rat substantia nigra (SN), in the present study we used fast cyclic voltammetry, tyrosine hydroxylase (TH) immunohistochemistry, Pe...

journal_title：Neurochemistry international

authors： Jiang H,Song N,Wang J,Ren LY,Xie JX

更新日期：2007-07-01 00:00:00

abstract：:P2Y purinergic receptors expressed in neurons and satellite glial cells (SGCs) of the trigeminal ganglion (TG) contribute to inflammatory and neuropathic pain. P2Y14 receptor expression is reported in the spinal cord, dorsal root ganglion (DRG), and TG. In present study, the role of P2Y14 receptor in the TG in inflamm...

journal_title：Neurochemistry international

authors： Lin J,Zhang YY,Liu F,Fang XY,Liu MK,Huang CL,Wang H,Liao DQ,Zhou C,Shen JF

更新日期：2019-12-01 00:00:00

abstract：:A number of principles have long guided research into serotonin neurochemistry and some of them are presently reconsidered with a slightly different outlook. An increasing amount of experimental data does not always support these older axioms and as more empirical observations are made, some of these may require modif...

journal_title：Neurochemistry international

authors： Kuhn DM,Wolf WA,Youdim MB

更新日期：1986-01-01 00:00:00

abstract：:The rat retinal ganglion cell (RGC) line RGC-5 constitutes a widely used model for studying physiological processes in retinal cells. In this paper we investigated the expression of clock and immediately early genes, and calcium mediated responses to physiological stimuli in differentiated and mitotically active RGC-5...

journal_title：Neurochemistry international

authors： Nieto PS,Acosta-Rodríguez VA,Valdez DJ,Guido ME

更新日期：2010-10-01 00:00:00