Reaching women where they are: eliminating the initial in-person medical abortion visit.

Abstract:

:The requirement that every woman desiring medical abortion must come in person to a clinical facility to obtain the drugs is a substantial barrier for many women. To eliminate this requirement in the United States, two key components of the standard initial visit would need to be restructured. First, alternatives to ultrasound and pelvic exam would need to be identified for ensuring that gestational age is within the limit for safe and effective treatment. This is probably feasible: for example, data from a large study suggest that in selected patients menstrual history is highly sensitive for this purpose. Second, the Food and Drug Administration would need to remove the medically unwarranted restriction on distribution of mifepristone. These two changes could allow provision of the service by a broader range of providers in nontraditional venues or even by telemedicine. Such options could have profound benefits in reducing cost and expanding access to abortion.

journal_name

Contraception

journal_title

Contraception

authors

Raymond EG,Grossman D,Wiebe E,Winikoff B

doi

10.1016/j.contraception.2015.06.020

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

190-3

issue

3

eissn

0010-7824

issn

1879-0518

pii

S0010-7824(15)00258-9

journal_volume

92

pub_type

杂志文章
  • Ultrasonographic and endocrine evaluation of ovarian function among Norplant implants users with regular menses.

    abstract::With the objective of evaluating the ovulatory function among long-term Norplant implants users with regular menstrual cycles, we undertook this prospective study including 11 Norplant implants users and 11 control women who were not using hormonal methods of fertility control. Exposed and unexposed women had had at l...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0010-7824(96)00179-5

    authors: Alvarez F,Brache V,Faundes A,Tejada AS,Thevenin F

    更新日期:1996-11-01 00:00:00

  • The zoapatle V--the effect of kauradienoic acid upon uterine contractility.

    abstract::Kauradienoic acid was obtained from the hexanic extract of M. tomentosa (Cerv) leaves by chromatographic separation. This substance influenced the in vitro contractility of the rat, dog and guinea pig uterine strips. It also induced strong contractions of the guinea pig uterus in vivo when administered intravenously, ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(83)90005-7

    authors: Lozoya X,Enríquez RG,Bejar E,Estrada AV,Girón H,Ponce-Monter H,Gallegos AJ

    更新日期:1983-03-01 00:00:00

  • Contraceptive use and risk of unintended pregnancy in California.

    abstract::California is home to more than one out of eight American women of reproductive age. Because California has a large, diverse and growing population, national statistics do not necessarily describe the reproductive health of California women. This article presents risk for pregnancy and sexually transmitted infections ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2004.01.012

    authors: Foster DG,Bley J,Mikanda J,Induni M,Arons A,Baumrind N,Darney PD,Stewart F

    更新日期:2004-07-01 00:00:00

  • Progestin-only pill use over 6 months postpartum.

    abstract:OBJECTIVES:To determine progestin-only pill (POP) use at 3 and 6 months postpartum among women who chose POPs at the postpartum visit. STUDY DESIGN:Secondary data analysis of a prospective observational study with telephone interviews at 3 and 6 months postpartum to assess contraceptive use. RESULTS:Of 440 women who ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2020.06.004

    authors: Uhm S,Garcia-Ruiz N,Creinin MD,Blanton A,Chen MJ

    更新日期:2020-10-01 00:00:00

  • Levonorgestrel plasma concentrations and hormone profiles after insertion and after one year of treatment with a levonorgestrel-IUD.

    abstract::Plasma concentrations of levonorgestrel, progesterone, estradiol, FSH and LH were measured in seven volunteers who had a levonorgestrel-releasing IUD inserted postmenstrually. Blood samples were collected twice weekly during a mean of 93 days immediately postmenstrually and during a mean of 41 days over the twelfth to...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(80)90003-7

    authors: Nilsson CG,Lähteenmäki P,Luukkainen T

    更新日期:1980-03-01 00:00:00

  • Rebound of medication abortion in Texas following updated mifepristone label.

    abstract:BACKGROUND:In 2013, Texas House Bill 2 (HB 2) placed restrictions on the use of medication abortion, which later were nullified with the 2016 FDA-approved mifepristone label. METHODS:Using data collected directly from Texas abortion facilities, we evaluated changes in the provision and use of medication abortion durin...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2019.01.001

    authors: Baum SE,White K,Hopkins K,Potter JE,Grossman D

    更新日期:2019-05-01 00:00:00

  • Effect of BMI and body weight on pregnancy rates with LNG as emergency contraception: analysis of four WHO HRP studies.

    abstract:OBJECTIVE:To estimate the effect of increased body weight and body mass index (BMI) on pregnancy rates with levonorgestrel (LNG) 1.5mg used as emergency contraception (EC). METHODS:The study reviewed data from 6873 women in four WHO-HRP randomized trials on EC conducted between 1993 and 2010. Participants took either ...

    journal_title:Contraception

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.contraception.2016.08.001

    authors: Festin MPR,Peregoudov A,Seuc A,Kiarie J,Temmerman M

    更新日期:2017-01-01 00:00:00

  • The effect of orally and vaginally administered misoprostol on inflammatory mediators and cervical ripening during early pregnancy.

    abstract:OBJECTIVES:The objective of the present study was to investigate the effect of vaginally and orally administered misoprostol on the local cervical inflammatory response. METHODS:Healthy women with a normal intrauterine pregnancy between 8 and 12 weeks of gestation presenting for an elective termination of pregnancy by...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.contraception.2005.02.012

    authors: Aronsson A,Ulfgren AK,Ståbi B,Stavreus-Evers A,Gemzell-Danielsson K

    更新日期:2005-07-01 00:00:00

  • A comparison of three daily coital diary designs and a phone-in regimen.

    abstract::Barrier contraceptive trials and disease intervention studies often utilize coital diaries to measure sexual exposures: dates and frequency of intercourse, product use, additional or alternative contraceptive use, and menstrual bleeding. The validity of these self-reported data is a matter of debate, but if used, bett...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0010-7824(01)00183-4

    authors: Hays MA,Irsula B,McMullen SL,Feldblum PJ

    更新日期:2001-03-01 00:00:00

  • Therapeutic abortion in early pregnancy with antiprogestogen RU486 alone or in combination with prostaglandin analogue (gemeprost).

    abstract::Abortion was attempted in 39 women in early pregnancy (less than 56 days amenorrhea) with the progesterone antagonist RU486 alone (150 mg per day for 4 days) or in combination with a PG analogue, 16,16-dimethyl-trans-delta 2-PGE1 (Gemeprost) in the form of a 1 mg vaginal pessary. Complete abortion was also attempted i...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0010-7824(86)90055-7

    authors: Cameron IT,Michie AF,Baird DT

    更新日期:1986-11-01 00:00:00

  • Mode of long-term antifertility effect of intrauterine neem treatment (IUNT).

    abstract::The mode of antifertility action of intrauterine neem treatment (IUNT) was studied. The effect of IUNT on ovarian functions and uterine responsiveness to ovarian hormones was examined in adult Wistar rats. The treated animals had normal reproductive cycles as indicated by the vaginal smears; serum progesterone levels ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(95)00018-6

    authors: Kaushic C,Upadhyay S

    更新日期:1995-03-01 00:00:00

  • Endometrial morphometry in users of intrauterine contraceptive devices and women with ovulatory dysfunctional uterine bleeding: a comparison with normal endometrium.

    abstract::Copper-bearing intrauterine contraceptive devices (IUCD) are commonly associated with menorrhagia. They cause certain morphological changes in the endometrium. These have been extensively reported and the mechanisms of menorrhagia have been investigated in a number of studies. By contrast, ovulatory dysfunctional uter...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章

    doi:10.1016/0010-7824(95)00040-h

    authors: Wang IY,Russell P,Fraser IS

    更新日期:1995-04-01 00:00:00

  • Effects of ethinyl estradiol and ibuprofen compared to placebo on endometrial bleeding, cervical mucus and the postcoital test in levonorgestrel subcutaneous implant users.

    abstract:BACKGROUND:The study was conducted to evaluate ethinyl estradiol (EE) or ibuprofen (IBU) compared to placebo (PL) on spotting and bleeding (S/B) and a postcoital test (PCT) in women using the levonorgestrel subcutaneous implant. Women experiencing excessive S/B were enrolled in a multicenter prospective randomized stud...

    journal_title:Contraception

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.contraception.2008.04.003

    authors: Archer DF,Philput CB,Levine AS,Cullins V,Stovall TG,Bacon J,Weber ME

    更新日期:2008-08-01 00:00:00

  • Postcoital use of anordrin and RU 486 for prevention of implantation in the rat.

    abstract::Because RU 486 synergizes with anordrin and its dihydroxylated metabolite to terminate established pregnancy in the rat and rabbit, the interactions of these agents were studied at two days postcoitally in the rat. RU 486 at a dose of 4 mg/kg did not prevent pregnancy when the animals were killed 12 days post insemina...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(93)90038-9

    authors: Chang CC,Wang WC,Bardin CW

    更新日期:1993-04-01 00:00:00

  • Medical abortion in the late first trimester: a systematic review.

    abstract:OBJECTIVE:To describe the efficacy, safety, and acceptability of medical abortion in the late first trimester. STUDY DESIGN:We searched PubMed and Cochrane databases for articles in any language that examined the success of medical abortion at gestational ages (>63 to≤84 days gestation). We sought articles that compar...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2018.11.002

    authors: Kapp N,Eckersberger E,Lavelanet A,Rodriguez MI

    更新日期:2019-02-01 00:00:00

  • Effect of obesity on the effectiveness of hormonal contraceptives: an individual participant data meta-analysis.

    abstract:OBJECTIVE:The objective of this investigation was to assess the potential effect of obesity on the effectiveness of hormonal contraceptives (HCs). STUDY DESIGN:A meta-analysis was conducted using individual participant data directly from the Phase 3 clinical trials of combination oral contraceptives (COCs) rather than...

    journal_title:Contraception

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.contraception.2015.07.016

    authors: Yamazaki M,Dwyer K,Sobhan M,Davis D,Kim MJ,Soule L,Willett G,Yu C

    更新日期:2015-11-01 00:00:00

  • Adherence to dual-method contraceptive use.

    abstract:BACKGROUND:Patient characteristics associated with adherence to dual-method contraceptive use are not known. STUDY DESIGN:Project PROTECT was a 24-month-long randomized trial designed to promote the use of dual methods of contraception using an individualized computer-based intervention or enhanced standard care couns...

    journal_title:Contraception

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.contraception.2011.01.023

    authors: Peipert JF,Zhao Q,Meints L,Peipert BJ,Redding CA,Allsworth JE

    更新日期:2011-09-01 00:00:00

  • How women anticipate coping after an abortion.

    abstract:BACKGROUND:There has been some study of women's emotional and psychological well-being after an abortion but no research into women's expectations, at the time of seeking an abortion, of how they will cope after the abortion. STUDY DESIGN:We abstracted counseling needs assessment forms of 5109 women who sought an abor...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2011.11.002

    authors: Foster DG,Gould H,Kimport K

    更新日期:2012-07-01 00:00:00

  • The effect of levonorgestrel-releasing intrauterine device on menorrhagia in women taking anticoagulant medication after cardiac valve replacement.

    abstract:BACKGROUND:This study was conducted to evaluate the effect of levonorgestrel-releasing intrauterine devices (LNG-IUDs) on menorrhagia in patients receiving anticoagulant therapy after cardiac valve replacement. STUDY DESIGN:Forty women with menorrhagia who underwent cardiac valve replacement and were taking anticoagul...

    journal_title:Contraception

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.contraception.2009.02.007

    authors: Kilic S,Yuksel B,Doganay M,Bardakci H,Akinsu F,Uzunlar O,Mollamahutoglu L

    更新日期:2009-08-01 00:00:00

  • Availability of pharmacist prescription of contraception in rural areas of Oregon and New Mexico.

    abstract:OBJECTIVE:To determine the availability of pharmacist prescribing of hormonal contraception in rural areas of two states. STUDY DESIGN:Cross-sectional survey. RESULTS:Overall, 42% of pharmacies prescribed contraception (Oregon: 46% and New Mexico 19%). A similar proportion of rural pharmacies reported offering pharma...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2019.11.005

    authors: Rodriguez MI,Garg B,Williams SM,Souphanavong J,Schrote K,Darney BG

    更新日期:2020-03-01 00:00:00

  • Do retroverted uteri adversely affect insertions and performance of IUDs?

    abstract::A large international multi-center IUD data set (N = 5520) coordinated by Family Health International was analysed to determine if the uterine position of a woman (anteverted, mid-positioned or retroverted) affects the ease of IUD insertion and if knowledge of uterine position would diminish insertion-related problems...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/0010-7824(90)90059-5

    authors: Chi IC,Farr G,Dominik R,Robinson N

    更新日期:1990-05-01 00:00:00

  • Subcutaneous DMPA vs. intramuscular DMPA: a 2-year randomized study of contraceptive efficacy and bone mineral density.

    abstract:BACKGROUND:A formulation of depot medroxyprogesterone acetate (DMPA) has been developed that allows subcutaneous injection (104 mg/0.65 mL; DMPA-SC) and achieves highly effective contraception with a similar tolerability profile to intramuscular DMPA (150 mg/mL; DMPA-IM). STUDY DESIGN:This randomized, evaluator-blinde...

    journal_title:Contraception

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.contraception.2009.02.005

    authors: Kaunitz AM,Darney PD,Ross D,Wolter KD,Speroff L

    更新日期:2009-07-01 00:00:00

  • A non-inferiority study of outpatient mifepristone-misoprostol medical abortion at 64-70 days and 71-77 days of gestation.

    abstract:OBJECTIVES:This open-label non-inferiority study assessed efficacy of a common outpatient medical abortion regimen among people with pregnancies 64-70 days and 71-77 days of gestation. STUDY DESIGN:We defined non-inferiority by a 6% margin of method success. People with intrauterine pregnancies 64-77 days' gestational...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2020.01.009

    authors: Dzuba IG,Chong E,Hannum C,Lichtenberg ES,Lugo Hernández EM,Ngoc NTN,Patel A,Rzayeva G,Sanhueza Smith P,Tsertsvadze G,Winikoff B

    更新日期:2020-05-01 00:00:00

  • A study of the efficacy of cervical ripening with nitric oxide donor versus placebo for cervical priming before second-trimester termination of pregnancy.

    abstract::This was a double-blind randomized control study to evaluate the efficacy of cervical priming by nitric oxide donor before second-trimester induced abortion. One-hundred healthy women with a singleton pregnancy between 14 and 20 weeks of gestation were randomized into either 40 mg isosorbide mononitrate or placebo, gi...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0010-7824(03)00170-7

    authors: Li CF,Chan CW,Ho PC

    更新日期:2003-10-01 00:00:00

  • Effect of polyphloretin phosphate on the contraceptive action of a polyethylene intrauterine device in rats.

    abstract::A polyethylene intrauterine device (IUD) inserted in one horn of the rat uterus on Day 2 of pregnancy prevented implantation in 9 out of 12 rats in the horn with the device. When polyphloretin phosphate (PPP), a substance known to inhibit alkaline phosphatase, was administered to such rats from Day 1 till Day 5 of pre...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(83)90016-1

    authors: Chaudhury MR

    更新日期:1983-08-01 00:00:00

  • Advancing non-directive pregnancy options counseling skills: A pilot Study on the use of blended learning with an online module and simulation.

    abstract:OBJECTIVE:Limitations on didactic time pose barriers to teaching non-directive pregnancy options counseling. This study set out to explore the use of an online module to support trainee performance in a pregnancy options counseling standardized-patient exercise implemented among third-year medical students, and to exam...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2016.03.005

    authors: Lupi C,Ward-Peterson M,Chang W

    更新日期:2016-10-01 00:00:00

  • Prospective randomized, controlled study of postoperative pain after titanium silicone rubber clip or Silastic ring tubal occlusion.

    abstract:OBJECTIVE:To determine if laparoscopic sterilization using the Filshie clip causes less postoperative pain as compared to the Falope ring during the first 24 h after surgery. STUDY DESIGN:Forty subjects were enrolled. Five milliliters of 0.5% bupivicaine was injected at each of the two incision sites and 5 mL was drip...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.contraception.2003.09.014

    authors: Pymar HC,Creinin MD,Vallejo MC

    更新日期:2004-02-01 00:00:00

  • Interest in and experience with IUD self-removal.

    abstract:OBJECTIVES:In the United States, the popularity of intrauterine devices (IUDs) is low despite many positive attributes such as high effectiveness and ease of use. The requirement that a clinician remove the IUD may limit US women's interest in the method. Our objective was to describe women's experience with self-remov...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2014.01.025

    authors: Foster DG,Grossman D,Turok DK,Peipert JF,Prine L,Schreiber CA,Jackson AV,Barar RE,Schwarz EB

    更新日期:2014-07-01 00:00:00

  • Fertility regulation in male rats and hamsters with alkylating agents.

    abstract::A single intratesticular injection of TEPA or Thio-TEPA induced a period of infertility lasting 1-2 months. Restoration of fertility was characterized by a reduction of the litter size resulting from the first inpregnation post-treatment. There was no evidence of tissue pathogenesis 6-12 months after treatment. ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(80)90061-x

    authors: Howe GR,Steward R

    更新日期:1980-08-01 00:00:00

  • Mid-trimester abortion by vaginal administration of 9-deoxo-16, 16-dimethyl-9-methylene-PGE2.

    abstract::9-Deoxo-16, 16-dimethyl-9-methylene-PGE2 is a new prostaglandin analogue which is stable in suppository form. Estimates of potential for gastrointestinal side effects in monkey in vivo indicated that the frequency of diarrhea was low with retention of uterine stimulating potency. In the present study the effect of the...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(80)90059-1

    authors: Bygdeman M,Christensen N,Gréen K,Lundström V

    更新日期:1980-08-01 00:00:00