Abstract:
:Fluid overload and prolonged mechanical ventilation lead to worse outcomes in critically ill children. However, the association between these variables in children following congenital heart surgery is unknown. The objectives of this study were to describe the association between fluid overload and duration of mechanical ventilation, oxygen requirement and radiologic findings of pulmonary and chest wall edema. This study is a retrospective chart review of patients who underwent congenital heart surgery between June 2010 and December 2013. Univariate and multivariate associations between maximum cumulative fluid balance and length of mechanical ventilation and OI were tested using the Spearman correlation test and multiple linear regression models, respectively. There were 85 eligible patients. Maximum cumulative fluid balance was associated with duration of mechanical ventilation (adjusted analysis beta coefficient = 0.53, CI 0.38-0.66, P < 0.001), length of stay in the pediatric intensive care unit (Spearman's correlation = 0.45, P < 0.001), and presence of chest wall edema and pleural effusions on chest radiograph (Mann-Whitney test, P = 0.003). Amount of red blood cells transfused and use of nitric oxide were independently associated with increased duration of mechanical ventilation (P = 0.012 and 0.014, respectively). Fluid overload is associated with prolonged duration of mechanical ventilation and PICU length of stay after congenital heart surgery. Fluid overload was also associated with physiological markers of respiratory restriction. A randomized controlled trial of a restrictive versus liberal fluid replacement strategy is necessary in this patient population, but in the meantime, accumulating observational evidence suggests that cautious use of fluid in the postoperative care may be warranted.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Sampaio TZ,O'Hearn K,Reddy D,Menon Kdoi
10.1007/s00246-015-1219-0subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1692-9issue
8eissn
0172-0643issn
1432-1971pii
10.1007/s00246-015-1219-0journal_volume
36pub_type
杂志文章abstract:OBJECTIVE:Heterotaxy syndrome is associated with complex cardiac malformations and cardiac conduction system abnormalities. Those with right atrial isomerism (RAI) have dual sinus nodes and dual atrioventricular nodes predisposing them to supraventricular tachycardia (SVT). Those with left atrial isomerism (LAI) lack a...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02087-2
更新日期:2019-06-01 00:00:00
abstract::We report a case of a 12-year-old boy with severe congenital aortic stenosis in whom magnetic resonance imaging (MRI) with delayed contrast enhancement demonstrated extensive subendocardial hyperenhancement within the left ventricle. The hyperenhancement was confirmed to be subendocardial infarct and fibrosis by histo...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-005-5891-3
更新日期:2006-05-01 00:00:00
abstract::Anomalous origin of left coronary artery (LCA) from the right coronary cusp with an intramural course is usually managed with unroofing of the intramural segment. Available literature demonstrates an uneventful course following surgery in most patients. Coronary stenosis following the unroofing procedure treated with ...
journal_title:Pediatric cardiology
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doi:10.1007/s00246-018-2005-6
更新日期:2019-01-01 00:00:00
abstract::Little data are published about right ventricular (RV) growth and function in infants and neonates after balloon pulmonary valvuloplasty (BPV) for critical valvular pulmonary stenosis (PS). We aimed to assess the RV growth and function during 1 year after BPV for critical valvular PS in neonates and infants. A total o...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02314-1
更新日期:2020-04-01 00:00:00
abstract::With improvements in technology and surgical technique, pediatric cardiologists are challenging surgeons to close symptomatic ventricular septal defects (VSDs) in ever smaller patients. Although delaying surgery may facilitate operative repair, early intervention decreases the period of time these patients require the...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-007-9016-z
更新日期:2008-01-01 00:00:00
abstract::Although liver fibrosis causes significant morbidity in the late postoperative period of the Fontan procedure, the diagnostic value of hyaluronic acid (HA), a serum marker of liver fibrosis, has not been established in Fontan patients. The purpose of this study was to determine whether increased serum HA concentration...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0827-9
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900180
更新日期:1997-07-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-017-1797-0
更新日期:2018-03-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-012-0466-6
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abstract::Double outlet right ventricle (DORV) was produced experimentally in the chick embryo by preventing the incorporation of the posteromedial conus into the left ventricle. This was accomplished by placing a ligature around the caudal end of the conus at a stage in which it is exclusively continuous with the right ventric...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02240456
更新日期:1982-01-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00794187
更新日期:1995-07-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-010-9802-x
更新日期:2011-01-01 00:00:00
abstract::This paper reviews the initial experience of radical correction of truncus arteriosus in the Soviet Union. The anatomy, hemodynamics, diagnosis and surgical technique are described in detail. Five patients were operated on; three survived. The two deaths in this series were due to mistakes in evaluating the indication...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02424960
更新日期:1984-04-01 00:00:00
abstract::Presented is a retrospective outcome study of a 15-year single institutional experience with a contemporary cohort of patients with hypoplastic left heart syndrome and complex that underwent a "Giessen Hybrid" stage I as initial palliation. Hybrid approach consisting of surgical bilateral pulmonary artery banding and ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-014-1015-2
更新日期:2015-02-01 00:00:00
abstract::Accessory atrioventricular pathways (AP) are the most common substrate for paroxysmal supraventricular tachycardia in infants and small children. Up-to-date data on AP ablation in infants and small children are limited. The aim of the present study was to gain additional insight into radiofrequency (RF) catheter ablat...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-016-1365-z
更新日期:2016-06-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0587-y
更新日期:2013-04-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s002460010169
更新日期:2001-03-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-020-02295-1
更新日期:2020-03-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00793955
更新日期:1992-07-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0698-0
更新日期:2013-10-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-012-0248-1
更新日期:2012-08-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-005-1274-z
更新日期:2006-05-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
abstract::From 1981 through June 1989, 59 children had surgery for a complete atrioventricular (AV) canal defect at Oregon Health Sciences University. We compared the morbidity, mortality, and hemodynamic status of 47 children with and 12 without Down's syndrome through review of operative, clinical, and cardiac catheterization...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00798209
更新日期:1992-04-01 00:00:00
abstract::The aim of this study is to evaluate the relationship between maternal single nucleotide polymorphisms (SNPs) of methylenetetrahydrofolate reductase (MTHFR) gene with plasma homocysteine (HCY) level and offspring congenital heart diseases (CHDs). 338 mothers with offspring CHDs as case group and 306 mothers of normal ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02449-1
更新日期:2020-11-21 00:00:00
abstract::We report on a 4-kg infant with Alagille syndrome and congenital heart disease consisting of atrial septal defect (ASD), patent ductus arteriosus (PDA), and severe peripheral pulmonic stenosis. He underwent successful orthotopic liver transplant along with catheter closure of the ASD and PDA using the Amplatzer device...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract::Pulmonary arterial hypertension (PAH) is a major cause of morbidity and mortality among patients with congenital heart disease (CHD). This study was designed to determine biomarker levels in patients with PAH associated with CHD (PAH-CHD) and CHD patients without PAH and to investigate the relationship of these potent...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0321-9
更新日期:2012-12-01 00:00:00
abstract::Children requiring reimplantation of a branch pulmonary artery (PA) are at risk for postoperative stenosis and impaired growth of the reimplanted PA. Outcomes and risk factors for reintervention and impaired growth are incompletely described. We reviewed data on patients who underwent reimplantation of a branch PA bet...
journal_title:Pediatric cardiology
pub_type: 杂志文章
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更新日期:2018-02-01 00:00:00
abstract::The HOXA1 gene plays a fundamental role in embryonic morphogenesis. Recent studies in humans and mice have indicated that HOXA1 plays a previously unrecognized role in cardiovascular system development. Congenital heart disease (CHD), particularly ventricular septal defect (VSD), might be a clinically isolated manifes...
journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2013-02-01 00:00:00
abstract::Non-invasive evaluation of right ventricular (RV) systolic function in neonates with pulmonary hypertension (PH) with traditional metrics including RV fractional area change (FAC) and tricuspid annular systolic plane excursion (TAPSE) has improved outcomes. Apical three-chamber (3C) RV-FAC, a novel tripartite assessme...
journal_title:Pediatric cardiology
pub_type: 杂志文章
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