Abstract:
Background:Our aim was to assess the risk of gastrointestinal (GI) hemorrhage associated with diabetes among patients taking low-dose aspirin (≤325 mg/day). Methods:A systematic search was conducted for publication in English and Chinese using term equivalents for "GI hemorrhage", "aspirin", and "diabetes mellitus" up till April 2020. Electronic databases include PUBMED, EMBASE, Cochrane Library databases, Chinese National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Database. Two independent authors searched databases and reviewed abstracts for comprehensive studies keeping adequate study quality. Data of weighted odds ratios were statistically evaluated and potential bias was checked. Results:Among 446 publications, eight case-control researches, including 1601 patients, were deemed for this meta-analysis. Patients with diabetes were associated with a higher risk of GI hemorrhage than patients without diabetes: the summary ORs were 3.10 (95% CI, 2.35-4.09). The heterogeneity of the reports was not significant (Chi2 = 3.39, P = 0.85; I2 = 0%). Conclusion:The meta-analysis showed that aspirin users with diabetes were more likely to have GI hemorrhage. Hence, when treating diabetics with aspirin, the increased risk of GI bleeding should be taken in consideration.
journal_name
Gastroenterol Res Practjournal_title
Gastroenterology research and practiceauthors
Wang Y,Wang W,Wang B,Wang Ydoi
10.1155/2020/9824615subject
Has Abstractpub_date
2020-08-03 00:00:00pages
9824615eissn
1687-6121issn
1687-630Xjournal_volume
2020pub_type
杂志文章,评审abstract::Perioperative chemotherapy improves overall survival in patients with oesophagogastric adenocarcinoma (OAC) and locoregional disease. The mainstay of perioperative chemotherapy in these patients is a platinum/fluoropyrimidine combination. The phase III FLOT4 trial has shown that the FLOT triplet regimen (oxaliplatin, ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2017/5651903
更新日期:2017-01-01 00:00:00
abstract:Background:Tumor regression grade (TRG) is widely used in gastrointestinal carcinoma to evaluate pathological responses to neoadjuvant chemotherapy (NCT), but whether it is an independent prognostic factor is still controversial. The aim of this study is to investigate the value of TRG in locally advanced gastric adeno...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/3435673
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journal_title:Gastroenterology research and practice
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journal_title:Gastroenterology research and practice
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doi:10.1155/2016/9256209
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journal_title:Gastroenterology research and practice
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doi:10.1155/2019/3467316
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abstract::Introduction. Neoadjuvant chemoradiotherapy and total mesorectal excision are considered the standard treatment for locally advanced rectal cancer. Various studies have reported pathological downstaging and a complete pathological response rate of 15%-27% following neoadjuvant chemoradiotherapy which has translated in...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
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journal_title:Gastroenterology research and practice
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/4134053
更新日期:2016-01-01 00:00:00
abstract::Distemonanthus benthamianus (Caesalpiniaceae) is a plant from the Cameroon pharmacopoeia very widely used in the treatment of many pathologies among which are gastrointestinal disorders. The main purpose of this study was to assess the healing properties of gastric ulcer from the methanolic extract of Distemonanthus b...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/8180323
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
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更新日期:2018-05-09 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/5984273
更新日期:2016-01-01 00:00:00
abstract::Colon cancer is a serious health problem, and novel preventive and therapeutical avenues are urgently called for. Delivery of proteins with anticancer activity through genetically modified bacteria provides an interesting, potentially specific, economic and effective approach here. Interestingly, bone morphogenetic pr...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/895462
更新日期:2012-01-01 00:00:00
abstract::Objective. The aim of the present study was to investigate whether pentraxin 3 (PTX3) can be a new noninvasive marker for prediction of liver fibrosis in patients with NAFLD. We also aimed to evaluate the relationship between PTX3 and atherosclerosis in patients with NAFLD. Method. Fifty-four male patients with biopsy...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/1417962
更新日期:2016-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/819395
更新日期:2014-01-01 00:00:00
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journal_title:Gastroenterology research and practice
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doi:10.1155/2020/8610653
更新日期:2020-04-03 00:00:00
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journal_title:Gastroenterology research and practice
pub_type:
doi:10.1155/2009/713937
更新日期:2009-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/8352756
更新日期:2018-08-08 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/2174957
更新日期:2018-03-04 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
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journal_title:Gastroenterology research and practice
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journal_title:Gastroenterology research and practice
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journal_title:Gastroenterology research and practice
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/343849
更新日期:2014-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/457150
更新日期:2012-01-01 00:00:00
abstract::Aim. Chronic gastritis was assessed serologically, endoscopically and histologically to identify correlations between these methods. Methods. Subjects comprised 319 patients who had provided informed consent. Serological assessment of chronic gastritis was based on the pepsinogen test method. Endoscopic gastritis and ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2011/631461
更新日期:2011-01-01 00:00:00
abstract:BACKGROUNDS:Magnifying endoscopy with blue laser imaging (ME-BLI) for diagnosis of early gastric cancer (EGC) is as effective as magnifying endoscopy with narrow-band imaging (ME-NBI). However, there are different EGCs in microstructure visualization between ME-BLI and ME-NBI. This study aimed to clarify the pathologic...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/8303046
更新日期:2017-01-01 00:00:00
abstract::Pancreatic adenocarcinoma is an aggressive disease that has poor outcomes despite maximal traditional therapies. Thus, treatment of this cancer demands innovative strategies to be used in addition to standing therapies in order to provide new avenues of care. Here, we describe the technique of using endoscopic ultraso...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2013/207129
更新日期:2013-01-01 00:00:00
abstract::Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postcon...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/2604032
更新日期:2016-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2015/146819
更新日期:2015-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2015/489363
更新日期:2015-01-01 00:00:00