Abstract:
PURPOSE:To evaluate computed tomography (CT) findings of nonspecific interstitial pneumonia (NSIP) based on the current classification of idiopathic interstitial pneumonias (IIPs) and elucidate a characteristic of previously diagnosed NSIP excluded from the current classification. MATERIALS AND METHODS:The study included 74 patients with biopsy-proven NSIP (idiopathic NSIP [I-NSIP], 39 patients; NSIP associated with connective tissue disease [CTD-NSIP], 35 patients). Among patients who were compatible with the current classification of IIPs, 29 and 21 were categorized as having current I-NSIP and current CTD-NSIP, respectively. The remaining 24 patients were categorized as having previous I-NSIP or previous CTD-NSIP due to the primary pathologic diagnosis of cellular NSIP or associated findings of acute inflammatory changes. CT findings were evaluated and compared among the four groups. RESULTS:Current I-NSIP was indicated by ground-glass attenuation and reticulation with traction bronchiectasis/bronchiolectasis in predominantly peribronchovascular areas of the lower lung zone. The previous I-NSIP group tended to show broader airspace consolidation than the current I-NSIP group (p = 0.068). The previous CTD-NSIP group showed significantly broader airspace consolidation than the current I-NSIP group (p = 0.035). CONCLUSION:Broad airspace consolidation is a characteristic of previously diagnosed CTD-NSIP excluded from the current classification of IIPs.
journal_name
Jpn J Radioljournal_title
Japanese journal of radiologyauthors
Tominaga J,Iwasawa T,Murota M,Arakawa H,Johkoh T,Yamano Y,Zaizen Y,Ichikado K,Hashisako M,Kondoh Y,Kataoka K,Okamoto M,Fujimoto K,Fukuoka J,Study Group of Creation of Radiological Paper from Japan in Diffuse Lung Disease.doi
10.1007/s11604-020-01036-xsubject
Has Abstractpub_date
2021-01-01 00:00:00pages
47-55issue
1eissn
1867-1071issn
1867-108Xpii
10.1007/s11604-020-01036-xjournal_volume
39pub_type
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