Abstract:
:Four cases of hypomelanosis of Ito with typical skin depigmentation and various noncutaneous findings were described. This neurocutaneous syndrome has been well documented by clinical investigations, especially computerized tomography and magnetic resonance imaging of the brain. The literature is surveyed giving special consideration to related neurologic manifestation. The most frequent neurologic abnormality was psychomotor retardation. Hearing loss in two patients and varicosis in one patient was striking. In one more patient, the symptoms resembled neurodegenerative disease.
journal_name
Neuropediatricsjournal_title
Neuropediatricsauthors
Griebel V,Krägeloh-Mann I,Michaelis Rdoi
10.1055/s-2008-1071300subject
Has Abstractpub_date
1989-11-01 00:00:00pages
234-7issue
4eissn
0174-304Xissn
1439-1899journal_volume
20pub_type
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