Abstract:
BACKGROUND AND OBJECTIVES:Increased serum homocysteine levels are related to vascular disease and increased mortality. The decrease of homocysteine is also associated with a worse prognosis in patients on hemodialysis; however, this relationship has not been well studied in other patients. Our goal is to study the prognosis of increased and decreased serum homocysteine levels in elderly patients admitted to a general internal medicine unit. PATIENTS AND METHODS:We included 239 patients (121 women and 118 men; mean age, 78 years) in which we determined serum homocysteine levels and study its relationship with vascular risk factors, vascular disease: ischemic heart disease, ischemic stroke and peripheral arterial disease, nutritional status, creatinine, albumin, folate and B12 vitamin. RESULTS:Mortality during hospitalization of patients with homocysteine levels below 9 μmol/l was 33%, 9% for those with levels between 9 and 20 μmol/l and 17% for those with levels above 20 μmol/l. Low homocysteine values were related to increased comorbidity, higher degree of weight loss and decreased serum albumin levels. In a survival analysis using Kaplan-Meier curves, increased homocysteine was associated with increased mortality especially in patients with vascular disease. CONCLUSION:In elderly patients with multiple comorbidities, both decreased and increased serum homocysteine levels are associated with increased mortality. :Antecedentes y objetivos: el aumento de la homocisteína se relaciona con la enfermedad vascular y un incremento de la mortalidad. La disminución de la homocisteína se asocia también con un peor pronóstico en enfermos en hemodiálisis; sin embargo, esta relación no ha sido bien estudiada en otro tipo de pacientes. El objetivo del estudio fue analizar el valor pronóstico de los niveles de homocisteína en enfermos ancianos pluripatológicos ingresados en un servicio general de medicina interna Pacientes y métodos: estudiamos a 239 pacientes (121 mujeres y 118 varones; edad media: 78 años) en los que determinamos la homocisteína sérica y la relacionamos con los factores de riesgo vascular, enfermedad vascular: cardiopatía isquémica, ACV isquémico y arteriopatía periférica, estado de nutrición, creatinina, albúmina, ácido fólico y vitamina B12. Resultados: la mortalidad durante el ingreso de los enfermos con homocisteína menor de 9 mol/l fue del 33%, del 9% cuando estaba entre 9 y 20 mol/l y del 17% si era superior a 20 mol/l. La disminución de la homocisteína se relacionó con mayor comorbilidad, pérdida de peso y disminución de la albúmina. A largo plazo, el aumento de la homocisteína se relacionó con mayor mortalidad, especialmente en los pacientes con enfermedad vascular. Conclusión: en los pacientes ancianos pluripatológicos tanto la disminución como el aumento de la homocisteína se asocian con una mayor mortalidad.
journal_name
Nutr Hospjournal_title
Nutricion hospitalariaauthors
Hernández-Betancor I,Martín-Ponce E,Martínez-Riera A,Viña-Rodríguez JJ,González-Reimers E,de la Vega-Prieto MJ,Santolaria Fdoi
10.3305/nh.2015.31.6.9011subject
Has Abstractpub_date
2015-06-01 00:00:00pages
2590-7issue
6eissn
0212-1611issn
1699-5198journal_volume
31pub_type
杂志文章abstract:INTRODUCTION:We may define Modular Parenteral Nutrition (MPN) as parenteral nutrition (PN) mixtures obtained from adding different macronutrients to standard formulations (SPN) both binary (amino acids and glucose) and ternary (amino acids, lipids, and glucose). OBJECTIVES:The aim of this study is to demonstrate that ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2007-07-01 00:00:00
abstract::Several complications are associated with the use of central venous catheters for total parenteral nutrition; cardiac tamponade is one of the most severe. The recent use of flexible materials made of silastic polymeric silicone has great decreased the incidence of this complication, but has not eliminated wholly. We r...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::We examined the possible changes undergone in the form of feeding post liver-transplant patients admitted to our Intensive Care Unit (ICU), comparing 1989 and 1992. As biological nutritional parameters, we reviewed blood lymphocyte values and albumin prior to the transplant, immediately after, seven days following and...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract::We present a clinical case of chronic radiation enteritis, with follow-up over 34 months, the main features of which were as follows: A 60-year-old female patient with adenocarcinoma of the rectum who required a left hemicolectomy (Hartmann), receiving chemotherapy with fluorouracil and external radiation therapy (45 ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
abstract::The objective of this work was to highlight the importance of testing in a realistic way, metallic nanoparticles-based products, used in the food sector in order to provide representative data for a realistic and accurate risk assessment. To this end we give a brief overview of the current use and applications of meta...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.20960/nh.2143
更新日期:2018-06-12 00:00:00
abstract:BACKGROUND:Weight is one of the most important parameters in assessing nutritional status. However, weight can be difficult to measure in elderly people who are unable to stand. Chumlea et al. created two equations to estimate weight in non-ambulatory patients using readily available body measurements. OBJECTIVE:The a...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2013.28.2.6320
更新日期:2013-03-01 00:00:00
abstract:INTRODUCTION:enteral nutrition therapy maintains and/or regains the nutritional status of the common patient in hospital settings, where anemia and malnutrition are food related and are very common diseases. OBJECTIVE:to determine and associate the presence of anemia and malnutrition in hospitalized patients with excl...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1628
更新日期:2018-06-22 00:00:00
abstract:INTRODUCTION:Health inequality is the difference in incidence, prevalence, mortality, volume of diseases and other adverse sanitary conditions that exist between groups of specific populations. OBJECTIVES:To analyze the possible nutritional inequalities between two educational centers of Madrid to promote healthy habi...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.29.1.6778
更新日期:2014-01-01 00:00:00
abstract:UNLABELLED:Hyperglycemia without previous history of diabetes mellitus (DM) is observed in a high percentage of patients in intensive care units (ICU). OBJECTIVE:To determine the behavior of glycemia in nondiabetic patients with hyperglycemia by administering two micronutrients. METHODS:A clinical trial was conducted...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.5.8526
更新日期:2015-05-01 00:00:00
abstract:INTRODUCTION:"tight calorie control" concept arose to avoid over- and under-feeding of patients. OBJECTIVE:to describe and validate a simplified predictive equation of total energy expenditure (TEE) in mechanically ventilated critically ill patients. METHODS:this was a secondary analysis of measurements of TEE by ind...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.3.9359
更新日期:2015-09-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:the aim of this study was to assess the fatty acid profile of two cured meat products of similar manufacturing processes and characteristics, dry-cured ham (JA) and cecina (CE), a type of dry-cured beef. The obtained results were discussed in terms of the effects that each singular fatty aci...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.1.8911
更新日期:2015-07-01 00:00:00
abstract::Registering the ingestive activity of laboratory animals can be carried out by using electronic scales connected to personal computers, thus gathering data files that allow calculation of the daily ingestion standards. The ingestion parameters most often used in the standard analysis include the number, size, and dura...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract::Malnutrition plays an important role in the rate of postoperative complications that interfere with our surgical activity, impairing immune response mechanisms; synthesis and regeneration processes are damaged and the fight against infection is altered. Preoperative and postoperative administration of diets enriched w...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2001-05-01 00:00:00
abstract::Chagasic megaesophagus is a chronic disease that courses with progressive dysphagia, regurgitation and protein-calorie malnutrition. Advanced or recurrent megaesophagus can be treated with Serra Dória's operation (cardioplasty, partial gastrectomy and gastrojejunal Roux-en-Y anastomosis). A nutritional evaluation was ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:fat-soluble vitamin deficiency may be a health problem not recognized in children and adolescents. OBJECTIVE:to estimate the prevalence and factors associated with the deficiency of vitamins A, D and E among adolescent students from Northeastern Brazil. METHODS:transversal study with adolescents aged 12 to...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1785
更新日期:2018-10-05 00:00:00
abstract:Introduction:Background and aims: intervention studies that evaluate the effect of rs16147 on metabolic response and weight change after dietary intervention are scarce. We propose to evaluate the role of the rs16147 genetic variant in the metabolic effects produced by a hypocaloric Mediterranean-pattern diet with high...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.02941
更新日期:2020-08-27 00:00:00
abstract:OBJECTIVE:the purpose of this investigation was to investigate the associations between nutritional status by Mini Nutritional Assessment (MNA) test and dysphagia by EAT-10 in elderly individuals requiring nutritional oral care in an acute hospital. PATIENTS:this was a cross-sectional survey covering a sample of 560 e...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1698
更新日期:2018-06-28 00:00:00
abstract::Objetivos: oligoelementos como zinc (Zn), hierro (Fe) y cobre (Cu) tienen una influencia significativa en el mantenimiento de la función inmune y del metabolismo normales; modulan la función immune e influyen en la susceptibilidad del organismo ante infecciones. Pero la relación entre trazas de estos elementos y la br...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.97
更新日期:2016-03-25 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the association of overweight and obesity with insulin resistance, hypertension, and hyperlipidemic among 12 to 15 year olds from private and public schools in Chiapas. METHODS:This was a cross-sectional study with a random selection of 259, 12 to 15 year old teenagers fro...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To assess enteral nutrition complications in a prospective cohort of patients admitted to the ICU. MATERIAL AND METHODS:Prospective, multicenter study of patients admitted to the ICU and that received enteral nutrition (EN). Demographical data, main diagnosis, and nutritional and severity indexes were includ...
journal_title:Nutricion hospitalaria
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:2005-07-01 00:00:00
abstract:INTRODUCTION:Iron is an essential micronutrient in the growing fetus. OBJECTIVE:The purpose of this study is to find the possible correlations that may exist between maternal and fetal iron status and newborn weight. MATERIAL AND METHODS:The study included 97 mothers scheduled to give birth by elective caesarean sect...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.238
更新日期:2017-06-05 00:00:00
abstract:INTRODUCTION:Malnutrition in children with cancer is a significant risk factor for negative outcomes, but in the clinical practice setting, it is difficult to pinpoint which factors operate to cause substantial weight loss and malnutrition in a given patient. Appetite-related hormones like ghrelin and leptin are among ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.20960/nh.1221
更新日期:2018-01-19 00:00:00
abstract::Objective: The aim of the present study was to describe the intake of sugar-sweetened beverages and to examine of associated factors among schoolchildren from Bogotá, Colombia. Methods: From a total of 8,136 schoolchildren and adolescents (age 9-17.9 years) taking part in the FUPRECOL Study. Sugar-sweetened beverages...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.250
更新日期:2017-03-30 00:00:00
abstract:BACKGROUND:Although changes in eating patterns may occur during gestation, predictors of these changes have not been explored. This study aimed to identify predictors of adherence to the Mediterranean diet (MD) from the first to second trimester of pregnancy. METHODS:A prospective study was conducted with 102 pregnant...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.3.8158
更新日期:2014-10-04 00:00:00
abstract::The modification of dietary patterns has led to a change in fatty acid consumption, with an increase in the consumption of ω-6 fatty acids and a marked reduction in the consumption of ω-3 fatty acids. This in turn has given rise to an imbalance in the ω-6/ω-3 ratio, which is now very different from the original 1:1 ra...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.1590/S0212-16112011000200013
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION:It has been reported that excessive gestational weight gain (GWG) during pregnancy is associated with an increase in adiposity indicators and metabolic disorders of the offspring. OBJECTIVE:The objective of this review, using the Institute of Medicine (IOM) criteria, was to analyze the association of exce...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.3305/nh.2015.31.4.8297
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Cervical cancer and cervical intraepithelial neoplasia (CIN) require a careful selection of conventional and complementary therapies. The inclusion of dietary supplements within the aforementioned treatments set the tone within treatments. However, there are no reports of what kind of supplements could be ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nutr hosp.v28in06.6816
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION:obesity often leads to deregulation and disrupting of the function of adipokines, which leads to various altered conditions, including metabolic syndrome (MetS). Adiponectin is one of the main adipokines secreted by adipocytes. The ADIPQ gene polymorphism rs266729 (-11377 C>G) is significantly associated w...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03204
更新日期:2020-12-15 00:00:00
abstract:Introduction:Objective: to identify cytokines and to associate them with several indexes of total and central adiposity in young female undergraduate students. Methods: 58 young female sophomore students, aged 18 to 25 years, from a Brazilian public university were evaluated. Both anthropometric measures (weight, heigh...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.02860
更新日期:2020-04-16 00:00:00
abstract:BACKGROUND & AIMS:Home enteral nutrition is used increasingly in pediatric populations. Our objective was to describe the profile of pediatric patients requiring this treatment. MATERIAL AND METHODS:All patients under 18 years old requiring treatment with home enteral nutrition between January 1995 and December 2004 w...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2012.27.5.5898
更新日期:2012-09-01 00:00:00