DNA methylation analysis of the temporal artery microenvironment in giant cell arteritis.

abstract：OBJECTIVE:To examine the effects of smoking on cartilage loss and pain at the knee in individuals with knee osteoarthritis. METHODS:159 men with symptomatic knee osteoarthritis who participated in a 30-month, prospective, natural history study of knee osteoarthritis were examined. The more symptomatic knee was imaged ...

journal_title：Annals of the rheumatic diseases

authors： Amin S,Niu J,Guermazi A,Grigoryan M,Hunter DJ,Clancy M,LaValley MP,Genant HK,Felson DT

更新日期：2007-01-01 00:00:00

abstract：:Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease, but many rheumatologists are not well acquainted with its management. The objective of this report is to produce evidence-based recommendations to guide rheumatologists and other health professionals in the treatment and follow-u...

journal_title：Annals of the rheumatic diseases

authors： Ozen S,Demirkaya E,Erer B,Livneh A,Ben-Chetrit E,Giancane G,Ozdogan H,Abu I,Gattorno M,Hawkins PN,Yuce S,Kallinich T,Bilginer Y,Kastner D,Carmona L

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:To investigate the significance of complement activation in patients with primary antiphospholipid syndrome (APS). METHODS:Thirty-six patients with primary APS, 42 control patients with non-systemic lupus erythematosus (SLE) connective tissue diseases, and 36 healthy volunteers were analysed retrospectively....

journal_title：Annals of the rheumatic diseases

authors： Oku K,Atsumi T,Bohgaki M,Amengual O,Kataoka H,Horita T,Yasuda S,Koike T

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To determine whether the number of patients required in a therapeutic trial that uses progression of radiological abnormalities as the outcome measure would be similar for multiple centres. METHODS:The progression of radiological damage to the fingers and wrists of patients with rheumatoid arthritis in five ...

journal_title：Annals of the rheumatic diseases

authors： Sharp JT,Wolfe F,Corbett M,Isomaki H,Mitchell DM,Furst DE,Sibley J,Shipley M

更新日期：1993-05-01 00:00:00

abstract：:Selenium is a trace element and an essential part of the enzyme glutathione peroxidase, which protects cells from oxidative damage. Selenium has been shown to have antiproliferative, anti-inflammatory, antiviral, and immune altering effects. Serum selenium concentrations in 101 patients with seropositive rheumatoid ar...

journal_title：Annals of the rheumatic diseases

authors： O'Dell JR,Lemley-Gillespie S,Palmer WR,Weaver AL,Moore GF,Klassen LW

更新日期：1991-06-01 00:00:00

abstract：OBJECTIVE:To further explore deiodinase iodothyronine type 2 (DIO2) as a therapeutic target in osteoarthritis (OA) by studying the effects of forced mechanical loading on in vivo joint cartilage tissue homeostasis and the modulating effect herein of Dio2 deficiency. METHODS:Wild-type and C57BL/6-Dio2(-/-) -mice were s...

journal_title：Annals of the rheumatic diseases

authors： Bomer N,Cornelis FM,Ramos YF,den Hollander W,Storms L,van der Breggen R,Lakenberg N,Slagboom PE,Meulenbelt I,Lories RJ

更新日期：2016-03-01 00:00:00

abstract：:A three phase study was designed to define further the sensitivity and specificity of symptomatic salicylate ototoxicity (primarily tinnitus) for serum salicylate concentrations. In phase one 260 patients with osteoarthritis and 112 with rheumatoid arthritis, none taking salicylates, were interviewed about their ear s...

journal_title：Annals of the rheumatic diseases

authors： Halla JT,Atchison SL,Hardin JG

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To examine the influence of intravenous pulsed methylprednisolone (MP) on bone mass. METHODS:38 patients (30 women) with various rheumatic disorders requiring intravenous MP pulse treatment were examined at baseline and after 6 months with dual energy x ray absorptiometry (DXA), measuring hip and lumbar spin...

journal_title：Annals of the rheumatic diseases

authors： Haugeberg G,Griffiths B,Sokoll KB,Emery P

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:The technique and results of a special oblique radiograph of the hip called the "faux profil" (FP) of the hip are described. The FP was evaluated for the detection of joint space narrowing in incipient osteoarthritis of the hip (OAH) as compared with the anteroposterior (AP) radiograph. METHODS:58 hips with ...

journal_title：Annals of the rheumatic diseases

authors： Lequesne MG,Laredo JD

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVES:In systemic sclerosis (SSc), vascular involvement is characterised by vascular endothelial growth factor (VEGF)-A/VEGF receptor (VEGFR) system disturbances. Neuropilin-1 (NRP1), a receptor for both class-3 semaphorins (Sema3s) and VEGF-A, is required for optimal VEGF-A/VEGFR-2 signalling. Here, we investigat...

journal_title：Annals of the rheumatic diseases

authors： Romano E,Chora I,Manetti M,Mazzotta C,Rosa I,Bellando-Randone S,Blagojevic J,Soares R,Avouac J,Allanore Y,Ibba-Manneschi L,Matucci-Cerinic M,Guiducci S

更新日期：2016-08-01 00:00:00

abstract：:The current management of autoimmunity involves the administration of immunosuppressive drugs coupled to symptomatic and functional interventions such as anti-inflammatory therapies and hormone replacement. Given the chronic nature of autoimmunity, however, the ideal therapeutic strategy would be to reinduce self-tole...

journal_title：Annals of the rheumatic diseases

authors： Mosanya CH,Isaacs JD

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:To investigate the prevalence of calcium phosphate mineral salt accumulation in degenerative supraspinatus 'tendinitis' compared with a normal sample of human tendons, and to determine whether there is an association of calcium salt deposition with pathological changes in the tendon extracellular matrix. ME...

journal_title：Annals of the rheumatic diseases

authors： Riley GP,Harrall RL,Constant CR,Cawston TE,Hazleman BL

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVES:To examine the expression of the natural killer (NK) antigen CD56, and T cell receptor delta chain antigen (TCR delta), expressed on the gamma delta T cell subset, in patients with scleroderma, and to correlate levels of expression with clinical characteristics. METHODS:Peripheral blood mononuclear cells (P...

journal_title：Annals of the rheumatic diseases

authors： Holcombe RF,Baethge BA,Wolf RE,Betzing KW,Stewart RM

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVES:Rheumatoid factor (RF) and anti-cyclic citrullinated protein/peptide antibodies (ACPA) are integrated in the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for rheumatoid arthritis (RA). The objectives of this study were to evaluate the technical ...

journal_title：Annals of the rheumatic diseases

authors： Van Hoovels L,Jacobs J,Vander Cruyssen B,Van den Bremt S,Verschueren P,Bossuyt X

更新日期：2018-05-01 00:00:00

abstract：:In osteoarthritis (OA), adult articular chondrocytes undergo phenotypic modulation in response to alterations in the environment owing to mechanical injury and inflammation. These processes not only stimulate the production of enzymes that degrade the cartilage matrix but also inhibit repair. With the use of in vitro ...

journal_title：Annals of the rheumatic diseases

authors： Goldring MB,Otero M,Tsuchimochi K,Ijiri K,Li Y

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To develop widely accepted international severity score for children and adult patients with familial Mediterranean fever (FMF) that can be easily applied, in research and clinical practice. METHODS:Candidate severity criteria were suggested by several FMF expert physicians. After three rounds of Delphi surv...

journal_title：Annals of the rheumatic diseases

authors： Demirkaya E,Acikel C,Hashkes P,Gattorno M,Gul A,Ozdogan H,Turker T,Karadag O,Livneh A,Ben-Chetrit E,Ozen S,FMF Arthritis Vasculitis and Orphan disease Research in pediatric rheumatology (FAVOR).

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVES:To present and analyse the literature sources regarding the management of Behçet disease (BD) identified during the systematic literature research, which formed the basis for the European League Against Rheumatism (EULAR) evidence-based recommendations for the management of BD. METHODS:Problem areas and rel...

journal_title：Annals of the rheumatic diseases

authors： Hatemi G,Silman A,Bang D,Bodaghi B,Chamberlain AM,Gul A,Houman MH,Kötter I,Olivieri I,Salvarani C,Sfikakis PP,Siva A,Stanford MR,Stübiger N,Yurdakul S,Yazici H

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:To measure hyaluronic acid (HA) levels, which are raised in active rheumatoid arthritis (RA), in patients with early RA, and to assess the correlation with clinical and laboratory indices of disease activity and with subsequent radiographic erosive status. PATIENTS AND METHODS:Patients fulfilling ACR criter...

journal_title：Annals of the rheumatic diseases

authors： Majeed M,McQueen F,Yeoman S,McLean L

更新日期：2004-09-01 00:00:00

abstract：:Feverfew, reputed by folklore to be effective in arthritis, has in vitro properties that could be beneficial in the control of inflammatory disease. Forty one female patients with symptomatic rheumatoid arthritis received either dried chopped feverfew (70-86 mg) or placebo capsules once daily for six weeks. Allocation...

journal_title：Annals of the rheumatic diseases

authors： Pattrick M,Heptinstall S,Doherty M

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To investigate the sympathetic and parasympathetic cardiovascular function in primary Sjögren's syndrome (SS) and to investigate the possible relation with ocular dryness. METHODS:41 (40 women) patients with primary SS, mean age 50 years (range 20-80) with a mean disease duration of eight years (range 1-30),...

journal_title：Annals of the rheumatic diseases

authors： Barendregt PJ,van Den Meiracker AH,Markusse HM,Tulen JH,Boomsma F,van Der Heijde GL,Veld AJ

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to test the hypothesis that the reason for non-response (caused by immunogenicity or not) to a first tumour necrosis factor (TNF) inhibitor defines whether a second TNF inhibitor will be effective. METHODS:This cohort study consisted of 292 consecutive patients with rheumatoid arthr...

journal_title：Annals of the rheumatic diseases

authors： Jamnitski A,Bartelds GM,Nurmohamed MT,van Schouwenburg PA,van Schaardenburg D,Stapel SO,Dijkmans BA,Aarden L,Wolbink GJ

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:Although shared decision making (SDM) is advocated in rheumatoid arthritis (RA) treatment, it is largely unclear when, how and to what extent SDM is applied in routine clinical care of patients with RA. This study aimed to investigate the level of SDM in RA treatment from an observer perspective and to asses...

journal_title：Annals of the rheumatic diseases

authors： Mathijssen EGE,Vriezekolk JE,Popa CD,van den Bemt BJF

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:Previous evidence suggests the role of psychological stress in triggering the onset of autoimmunity. We aimed to investigate whether stress following major and minor life events could precede the onset of primary Sjögren's syndrome (pSS). The role of coping strategies and social support, as compensating buff...

journal_title：Annals of the rheumatic diseases

authors： Karaiskos D,Mavragani CP,Makaroni S,Zinzaras E,Voulgarelis M,Rabavilas A,Moutsopoulos HM

更新日期：2009-01-01 00:00:00

abstract：:We have compared the distribution of histocompatibility antigens of 22 Turkish and 14 British patients with Behçet's disease with those of their respective controls. There was a strong association of B5, specifically its Bw51 split, with the disease. A modest increase in the incidence of HLA B27 was noted in British p...

journal_title：Annals of the rheumatic diseases

authors： Yazici H,Chamberlain MA,Schreuder I,D'Amaro J,Muftuoglu M

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:Treatment with tumour necrosis factor inhibitors (TNF-i) plus methotrexate (MTX), but not MTX monotherapy alone, inhibits joint damage progression even at higher levels of disease activity. Such disassociation of disease activity and structural damage has not been shown for biological agents other than TNF-i...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Avila JC,Aletaha D

更新日期：2012-05-01 00:00:00

abstract：:HLA A, B, and C antigens were studied in 25 patients with ankylosing hyperostosis. There was no evidence of an increased frequency of any antigen in association with the condition itself. However, a high frequency of several antigens was found, reflecting the predominance of Jewish patients in the series. ...

journal_title：Annals of the rheumatic diseases

authors： Perry JD,Wolf H,Festenstein H,Storey GO

更新日期：1979-02-01 00:00:00

abstract：OBJECTIVES:To assess the association of body mass index (BMI) with modifiable cardiovascular disease (CVD) risk factors in patients with rheumatoid arthritis (RA). METHODS:BMI, disease activity, selected CVD risk factors and CVD medication were assessed in 378 (276 women) patients with RA. Patients exceeding accepted ...

journal_title：Annals of the rheumatic diseases

authors： Stavropoulos-Kalinoglou A,Metsios GS,Panoulas VF,Douglas KM,Nevill AM,Jamurtas AZ,Kita M,Koutedakis Y,Kitas GD

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:The Psoriatic Arthritis Impact of Disease (PsAID) Questionnaire is a recently developed patient-reported outcome measure (PROM) of disease impact in psoriatic arthritis (PsA). We set out to assess the validity in an independent cohort of patients, estimate the minimally important difference for improvement a...

journal_title：Annals of the rheumatic diseases

authors： Holland R,Tillett W,Korendowych E,Cavill C,Waldron N,Brooke M,McHugh NJ

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Several inflammatory conditions are associated with an increased risk of lymphoma. The specific features of inflammation that mediate this risk are unknown. There are few studies on whether ankylosing spondylitis increases the risk of lymphoma. Besides inflammation-lymphoma aetiology, information on risk of ...

journal_title：Annals of the rheumatic diseases

authors： Askling J,Klareskog L,Blomqvist P,Fored M,Feltelius N

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To determine if serum urate concentration is associated with development of hypertension in young adults. METHODS:Retrospective cohort analysis from 4752 participants with available serum urate and without hypertension at baseline from the Coronary Artery Risk Development in Young Adults (CARDIA) study; a mi...

journal_title：Annals of the rheumatic diseases

authors： Gaffo AL,Jacobs DR Jr,Sijtsma F,Lewis CE,Mikuls TR,Saag KG

更新日期：2013-08-01 00:00:00