Abstract：
:Since the FDA approval of Spritam, there has been a growing interest in the application of 3D printing in pharmaceutical science. 3D printing is a method of manufacturing involving the layer-by-layer deposition of materials to create a final product according to a digital model. There are various techniques used to achieve this method of printing including the SLS, SLA, FDM, SSE and PB-inkjet printing. In biomanufacturing, bone and tissue engineering involving 3D printing to create scaffolds, while in pharmaceutics, 3D printing was applied in drug development, and the fabrication of drug delivery devices. This paper aims to review the use of some 3D printing techniques in the fabrication of oral solid dosage forms. FDM, SLA SLS, and PB-Inkjet printing processes were found suitable for the fabrication of oral solid dosage forms, though a great deal of the available research was focused on fused deposition modelling due to its availability and flexibility. Process parameters as well as strategies to control the characteristics of printed dosage forms are analysed and discussed. The review also presents the advantages and possible limitations of 3D printing of medicines.
journal_name
J Pharm Scijournal_title
Journal of pharmaceutical sciencesauthors
Okafor-Muo OL,Hassanin H,Kayyali R,ElShaer Adoi
10.1016/j.xphs.2020.08.029subject
Has Abstractpub_date
2020-12-01 00:00:00pages
3535-3550issue
12eissn
0022-3549issn
1520-6017pii
S0022-3549(20)30555-4journal_volume
109pub_type
杂志文章,评审abstract：:An assay is described for the determination of the H2-receptor antagonist, cimetidine, in human plasma and urine. Alkalinized plasma or urine was extracted with methylene chloride, the organic phase was evaporated, and the reconstituted residue was analysed by high-pressure liquid chromatography (HPLC) using a reverse...
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doi：10.1002/jps.2600660620
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更新日期：2018-05-01 00:00:00
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