Abstract:
:Esophageal adenocarcinoma (EAC) has increased dramatically in the past 3 decades, making its precursor lesion Barrett's esophagus (BE) an important clinical problem. Effective interventions are available, but overall outcomes remain unchanged. Most of the BE population remains undiagnosed; most EACs are diagnosed late, and most BE patients will never progress to cancer. These epidemiologic factors make upper endoscopy an inefficient and ineffective strategy for BE diagnosis and risk stratification. In the current review, biomarkers for diagnosis, risk stratification, and predictors of response to therapy in BE are discussed.
journal_name
Gastroenterol Clin North Amjournal_title
Gastroenterology clinics of North Americaauthors
Bansal A,Fitzgerald RCdoi
10.1016/j.gtc.2015.02.008subject
Has Abstractpub_date
2015-06-01 00:00:00pages
373-90issue
2eissn
0889-8553issn
1558-1942pii
S0889-8553(15)00025-4journal_volume
44pub_type
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