Biomarkers in Barrett's Esophagus: Role in Diagnosis, Risk Stratification, and Prediction of Response to Therapy.

Abstract:

:Esophageal adenocarcinoma (EAC) has increased dramatically in the past 3 decades, making its precursor lesion Barrett's esophagus (BE) an important clinical problem. Effective interventions are available, but overall outcomes remain unchanged. Most of the BE population remains undiagnosed; most EACs are diagnosed late, and most BE patients will never progress to cancer. These epidemiologic factors make upper endoscopy an inefficient and ineffective strategy for BE diagnosis and risk stratification. In the current review, biomarkers for diagnosis, risk stratification, and predictors of response to therapy in BE are discussed.

authors

Bansal A,Fitzgerald RC

doi

10.1016/j.gtc.2015.02.008

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

373-90

issue

2

eissn

0889-8553

issn

1558-1942

pii

S0889-8553(15)00025-4

journal_volume

44

pub_type

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