当前位置： SCI文献检索 > JOURNAL OF CRITICAL CARE期刊下所有文献 > Risk factors for fluconazole-resistant invasive candidiasis in intensive care unit patients: An analysis from the China Survey of Candidiasis study.

Risk factors for fluconazole-resistant invasive candidiasis in intensive care unit patients: An analysis from the China Survey of Candidiasis study.

Abstract：

PURPOSE:To assess the risk factors for invasive Candida infection (ICI) caused by fluconazole-resistant (Flu-R) Candida species in intensive care unit (ICU) patients. MATERIALS AND METHODS:Data from China Survey of Candidiasis study were analyzed. Patients with proven ICI were classified into fluconazole-sensitive (Flu-S) and Flu-R groups. Independent risk factors for Flu-R ICI were identified using a multivariate logistic regression. RESULTS:Forty-one percent of ICI patients were infected with Flu-R Candida. Significantly more patients had Candida colonization, intra-abdominal hypertension, and antifungal therapy at least 7 days before diagnosis; fewer patients had gastrointestinal perforation, systemic inflammatory response syndrome manifestation, and fluoroquinolone exposure in the Flu-R group. Furthermore, hospital or ICU stay before onset of infection was longer in the Flu-R group than in the Flu-S group (hospital or ICU stay: 19 vs 13 days or 10.5 vs 8 days, P < .05). Also, it was demonstrated as an independent risk factor for Flu-R Candida infection. CONCLUSION:As many as 41% of ICI patients were infected with Flu-R Candida, and the main risk factor was longer ICU stay before onset of ICI, implying that caution should be exercised when treating patients who have been long stayed in ICU with fluconazole as the first-line drug before testing isolates for drug sensitivity.

journal_name

J Crit Care

journal_title

Journal of critical care

authors

Liao X,Qiu H,Li R,Guo F,Liu W,Kang M,Kang Y,China-SCAN Team.

doi

10.1016/j.jcrc.2015.04.002

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

862.e1-5

issue

4

eissn

0883-9441

issn

1557-8615

pii

S0883-9441(15)00147-1

journal_volume

30

pub_type

杂志文章

相关文献

JOURNAL OF CRITICAL CARE文献大全
  • A study of once-daily amikacin with low peak target concentrations in intensive care unit patients: pharmacokinetics and associated outcomes.

    abstract：PURPOSE:The aim of this study was to assess the pharmacokinetics of individualized amikacin single-dosage regimens targeting low peak serum concentrations in a population of intensive care unit (ICU) patients, and to describe the outcomes associated with this dosing strategy. MATERIALS AND METHODS:In this prospective,...

    journal_title：Journal of critical care

    pub_type： 临床试验,杂志文章

    doi：10.1053/jcrc.2003.50003

    authors： Bacopoulou F,Markantonis SL,Pavlou E,Adamidou M

    更新日期：2003-06-01 00:00:00

  • Plasma syndecan-1 levels identify a cohort of patients with severe sepsis at high risk for intubation after large-volume intravenous fluid resuscitation.

    abstract：PURPOSE:Sepsis damages the endothelial glycocalyx, contributing to fluid extravasation, organ injury, and death. Our goal was to determine if syndecan-1 level is associated with the risk of intubation and modifying effect of intravenous fluids (IVFs) in these patients. METHODS:Syndecan-1 was measured at enrollment in ...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2016.06.027

    authors： Puskarich MA,Cornelius DC,Tharp J,Nandi U,Jones AE

    更新日期：2016-12-01 00:00:00

  • The safety of synthetic colloid in critically ill patients with severe traumatic brain injuries.

    abstract：PURPOSE:Although 4% albumin is associated with increased mortality in patients with traumatic brain injury (TBI), evidence concerning the safety of synthetic colloids is lacking. We aimed to determine if there is an association between synthetic colloids and mortality in patients with severe TBI. MATERIALS AND METHODS...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2010.12.001

    authors： Sekhon MS,Dhingra VK,Sekhon IS,Henderson WR,McLean N,Griesdale DE

    更新日期：2011-08-01 00:00:00

  • The role of human metapneumovirus in the critically ill adult patient.

    abstract：PURPOSE:The purpose of the study is to describe the role of human metapneumovirus (hMPV) infection in critical illness and acute respiratory distress syndrome (ARDS). MATERIALS AND METHODS:We collected clinical and demographic information from a retrospective chart review, comparing patients with and without an intens...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2015.09.035

    authors： Hasvold J,Sjoding M,Pohl K,Cooke C,Hyzy RC

    更新日期：2016-02-01 00:00:00

  • Contributors to frailty in critical illness: Multi-dimensional analysis of the Clinical Frailty Scale.

    abstract：PURPOSE:Frailty in critical illness is common and associated with poor outcomes, however little is known about contributing factors. We compared the Clinical Frailty Scale (CFS) with a multi-dimensional validated tool, the Edmonton Frail Scale (EFS), and investigated which health domains are affected by frailty in ICU....

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2019.04.032

    authors： Darvall JN,Greentree K,Braat MS,Story DA,Lim WK

    更新日期：2019-08-01 00:00:00

  • The oxygenation ratio during mechanical ventilation in children: the role of tidal volume and positive end-expiratory pressure.

    abstract：OBJECTIVE:The objective of this study is to analyze the role of tidal volume (Vt) and positive end-expiratory pressure on the oxygenation ratio (OR) (Pao(2)/Fio(2)) during mechanical ventilation (MV) in children with a normal pulmonary gas exchange on admission. METHODS:A retrospective cohort study of children with an...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2008.03.036

    authors： Halbertsma FJ,Vaneker M,Pickkers P,Hoeven JG

    更新日期：2009-06-01 00:00:00

  • COVID-19 and non-COVID ARDS patients demonstrate a distinct response to low dose steroids- A retrospective observational study.

    abstract：:Patients with COVID-19 ARDS have distinct physiological and immunological phenotypes compared to patients with non-COVID ARDS. Patients with COVID-19 ARDS (n = 32) had a significant improvement in PaO2: FiO2 ratio (p = 0.046) following low-dose steroid treatment, unlike patients with non-COVID ARDS (n = 16) (p = 0.529...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2020.11.012

    authors： Longobardo A,Snow TAC,Montanari C,Shulman R,Singer M,Arulkumaran N

    更新日期：2020-11-21 00:00:00

  • Efficacy of noninvasive mechanical ventilation in prevention of intubation and reintubation in the pediatric intensive care unit.

    abstract：PURPOSE:To determine the efficiency of noninvasive mechanical ventilation (NIV) both in protection from intubation and in preventing reintubation of postextubation in patients in the pediatric intensive care unit (PICU). METHODS:A prospective observational study was conducted in a multidisciplinary 10-bed tertiary PIC...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2015.12.013

    authors： Yaman A,Kendirli T,Ödek Ç,Ateş C,Taşyapar N,Güneş M,İnce E

    更新日期：2016-04-01 00:00:00

  • Liquid ventilation attenuates pulmonary oxidative damage.

    abstract：PURPOSE:Liquid perfluorochemicals reduce the production of reaction oxygen species by alveolar macrophages. We sought to determine whether the use of liquid perfluorochemicals in vivo during liquid ventilation would attenuate oxidative damage to the lung. MATERIALS AND METHODS:Healthy infant piglets (n = 16) were inst...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/s0883-9441(99)90004-7

    authors： Steinhorn DM,Papo MC,Rotta AT,Aljada A,Fuhrman BP,Dandona P

    更新日期：1999-03-01 00:00:00

  • Apnea testing using the oxygen insufflation method for diagnosis of brain death may compromise pulmonary function.

    abstract：INTRODUCTION:The aim of our study was to compare the reliability and safety of the classical I-AT with the continuous positive airway pressure apnea test (CPAP-AT). MATERIAL AND METHODS:In the group of 48 patients (group O), an I-AT was performed at the end of BD diagnostic procedures, and approximately 1-1.5h later C...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2017.10.038

    authors： Sołek-Pastuszka J,Sawicki M,Iwańczuk W,Kojder K,Saucha W,Czajkowski Z,Chełstowski K,Bohatyrewicz R

    更新日期：2018-04-01 00:00:00

  • Ultrasound-guided laryngeal air column width difference and the cuff leak volume in predicting the effectiveness of steroid therapy on postextubation stridor in adult. Are they useful?

    abstract：OBJECTIVE:To evaluate the effectiveness of steroids therapy on postextubation stridor (PES) depending on the clinical response, the ultrasound guided laryngeal air column width difference (LACWD) and the cuff leak volume (CLV). DESIGN:Prospective, observer-blinded study. SETTING:Carried out in intensive care unit in ...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2016.07.007

    authors： El-Baradey GF,El-Shmaa NS,Elsharawy F

    更新日期：2016-12-01 00:00:00

  • Identifying essential elements to include in Intensive Care Unit to hospital ward transfer summaries: A consensus methodology.

    abstract：PURPOSE:Transitions of care from the intensive care unit (ICU) to a hospital ward are high risk and contingent on effective communication. We sought to identify essential information elements to be included in an ICU to hospital ward transfer summary tool, and describe tool functionality and composition perceived to be...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2018.10.001

    authors： ICU Transfer Summary Consensus Panel,.,de Grood C,Job McIntosh C,Boyd JM,Zjadewicz K,Parsons Leigh J,Stelfox HT

    更新日期：2019-02-01 00:00:00

  • Implementing and sustaining an early rehabilitation program in a medical intensive care unit: A qualitative analysis.

    abstract：PURPOSE:Early rehabilitation programs in a medical intensive care unit can improve patient outcomes, but clinicians face barriers in implementing and sustaining such programs. We sought to describe a multidisciplinary team perspective regarding how to implement and sustain a successful early rehabilitation program. ME...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2015.03.019

    authors： Eakin MN,Ugbah L,Arnautovic T,Parker AM,Needham DM

    更新日期：2015-08-01 00:00:00

  • Surveillance cultures in intensive care units: a nationwide survey on current practice providing future perspectives.

    abstract：PURPOSE:To explore the extent of surveillance culture (SC) implementation underlying motives for obtaining SC and decision making based on the results. MATERIALS AND METHODS:A questionnaire was distributed to Heads of Department (HODs) and microbiologists within all intensive care departments in the Netherlands. RESU...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2014.05.018

    authors： Scholte JB,van Mook WN,Linssen CF,van Dessel HA,Bergmans DC,Savelkoul PH,Roekaerts PM

    更新日期：2014-10-01 00:00:00

  • Comparison of traditional microbiological culture and 16S polymerase chain reaction analyses for identification of preoperative airway colonization for patients undergoing lung resection.

    abstract：PURPOSE:Preoperative airway colonization is associated with increased risk of postoperative respiratory complications following lung resection. This study compares the rates of preoperative lower respiratory tract colonization identified by traditional culture and novel 16S polymerase chain reaction (PCR) tests. MATER...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2018.04.013

    authors： Howitt SH,Blackshaw D,Fontaine E,Hassan I,Malagon I

    更新日期：2018-08-01 00:00:00

  • Myocardial oxygen consumption during dobutamine infusion in endotoxemic pigs.

    abstract：PURPOSE:Dobutamine infusion is used to increase whole-body oxygen delivery in septic patients to satisfy unmet oxygen demand of hypoxic tissues. However, dobutamine infusion also increases myocardial work and myocardial oxygen consumption. Our goal was to determine the importance of this effect as a fraction of the inc...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/s0883-9441(99)90025-4

    authors： Herbertson MJ,Russell JA,Walley KR

    更新日期：1999-09-01 00:00:00

  • Full Outline of UnResponsiveness score and Glasgow Coma Scale in medical patients with altered sensorium: interrater reliability and relation to outcome.

    abstract：PURPOSE:Full Outline of UnResponsiveness, or FOUR score (FS), is a recently described scoring system for evaluation of altered sensorium. This study examined interrater reliability for FS and Glasgow Coma Scale (GCS) among medical patients with altered mental status and compared outcome predictability of GCS, FS, and S...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2012.06.009

    authors： Gujjar AR,Jacob PC,Nandhagopal R,Ganguly SS,Obaidy A,Al-Asmi AR

    更新日期：2013-06-01 00:00:00

  • Multipronged strategy to reduce routine-priority blood testing in intensive care unit patients.

    abstract：PURPOSE:The purpose of the study is to reduce unnecessary ordering of routine-priority blood tests. METHODS:In this before-after study, we studied all patients admitted to a 15-bed tertiary intensive care unit (ICU) from July 1, 2011, to June 27, 2013. Based on input from intensivists, acceptable indications for order...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2015.09.013

    authors： Merkeley HL,Hemmett J,Cessford TA,Amiri N,Geller GS,Baradaran N,Norena M,Wong H,Ayas N,Dodek PM

    更新日期：2016-02-01 00:00:00

  • Quick sequential organ failure assessment compared to systemic inflammatory response syndrome for predicting sepsis in emergency department.

    abstract：PURPOSE:It is unclear whether quick sequential (sepsis-related) organ failure assessment (qSOFA) also has prognostic value for organ failure in patients with a suspected infection. The aim of this study was to determine whether qSOFA has prognostic value when compared to systemic inflammatory response syndrome (SIRS) i...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2017.06.020

    authors： Park HK,Kim WY,Kim MC,Jung W,Ko BS

    更新日期：2017-12-01 00:00:00

  • Increased incidence of diuretic use in critically ill obese patients.

    abstract：OBJECTIVE:Sodium retention occurs commonly in cardiac and liver disease, requiring the administration of diuretics to restore fluid balance. Whether obesity is associated with sodium retention has not been fully evaluated. METHODS:In a large single-center cohort of critically ill patients, we evaluated whether admissi...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2015.01.023

    authors： de Louw EJ,Sun PO,Lee J,Feng M,Mark RG,Celi LA,Mukamal KJ,Danziger J

    更新日期：2015-06-01 00:00:00

  • The simulation theater: a theoretical discussion of concepts and constructs that enhance learning.

    abstract：:The increasing role of simulation in medical education has paralleled the advancement of this technology. Full environment simulation (FES) can be used to effectively replicate rare medical catastrophes with exacting realism. It has been suggested that emotion can significantly enhance learning by producing memories t...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2007.12.003

    authors： Bryson EO,Levine AI

    更新日期：2008-06-01 00:00:00

  • The diagnosis of myocardial infarction in critically ill patients: an agreement study.

    abstract：PURPOSE:The aim of the study was to assess agreement among 4 intensivists in diagnosing myocardial infarction (MI) in critically ill patients based on screening electrocardiograms (ECGs) and cardiac troponin (cTn) levels. METHODS:Consecutive patients admitted to a medical-surgical intensive care unit (ICU) underwent s...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2008.08.012

    authors： Lim W,Tkaczyk A,Holinski P,Qushmaq I,Jacka M,Khera V,Devereaux PJ,Terrenato I,Schunemann H,Heels-Ansdell D,Crowther M,Cook D

    更新日期：2009-09-01 00:00:00

  • Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients.

    abstract：OBJECTIVE:Serum concentrations of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, may contribute to endothelial dysfunction and organ failure in sepsis. We aimed at investigating ADMA levels as a potential diagnostic or prognostic biomarker in critically ill patients. METHODS:Two ...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2013.05.016

    authors： Koch A,Weiskirchen R,Kunze J,Dückers H,Bruensing J,Buendgens L,Matthes M,Luedde T,Trautwein C,Tacke F

    更新日期：2013-12-01 00:00:00

  • The influence of anesthesia on heart rate complexity during elective and urgent surgery in 128 patients.

    abstract：BACKGROUND:As an emerging "new vital sign," heart rate complexity (by sample entropy [SampEn]) has been shown to be a useful trauma triage tool by predicting occult physiologic compromise and need for life-saving interventions. Sample entropy may be confounded by anesthesia possibly limiting its value intraoperatively....

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2014.08.008

    authors： Naraghi L,Peev MP,Esteve R,Chang Y,Berger DL,Thayer SP,Rattner DW,Lillemoe KD,Kaafarani H,Yeh DD,de Moya MA,Fagenholz PJ,Velmahos GS,King DR

    更新日期：2015-02-01 00:00:00

  • Ciprofloxacin pharmacokinetics in critically ill patients: a prospective cohort study.

    abstract：PURPOSE:Optimal dosing of antibiotics is important for efficacy and avoidance of resistance. Fluoroquinolones are frequently used to treat severe infections in critically ill patients. We studied ciprofloxacin pharmacokinetics after administration of 400 mg twice a day (bid) intravenously (IV). MATERIAL AND METHODS:Se...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2007.11.011

    authors： van Zanten AR,Polderman KH,van Geijlswijk IM,van der Meer GY,Schouten MA,Girbes AR

    更新日期：2008-09-01 00:00:00

  • Extracorporeal membrane oxygenation (ECMO) as a treatment strategy for severe acute respiratory distress syndrome (ARDS) in the low tidal volume era: A systematic review.

    abstract：OBJECTIVE:To evaluate the hospital survival in patients with severe ARDS managed with ECMO and low tidal volume ventilation as compared to patients managed with low tidal volume ventilation alone. METHODS:Electronic databases were searched for studies of at least 10 adult patients with severe ARDS comparing the use of...

    journal_title：Journal of critical care

    pub_type： 杂志文章,评审

    doi：10.1016/j.jcrc.2017.04.041

    authors： Tillmann BW,Klingel ML,Iansavichene AE,Ball IM,Nagpal AD

    更新日期：2017-10-01 00:00:00

  • Furosemide and Albumin for Diuresis of Edema (FADE): A parallel-group, blinded, pilot randomized controlled trial.

    abstract：PURPOSE:To assess the feasibility of a trial evaluating whether hyperoncotic albumin, in addition to diuretics, improves diuresis and facilitates liberation from mechanical ventilation in critically ill adults. MATERIALS AND METHODS:We randomized 46 hemodynamically stable patients with hypoalbuminemia, prescribed diur...

    journal_title：Journal of critical care

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jcrc.2018.07.020

    authors： Oczkowski SJW,Klotz L,Mazzetti I,Alshamsi F,Chen ML,Foster G,Meade MO,Hamielec C

    更新日期：2018-12-01 00:00:00

  • Adipose tissue lipolysis and circulating lipids in acute and subacute critical illness: effects of shock and treatment.

    abstract：PURPOSE:The purpose of this study is to assess lipid metabolism at the tissue level in critically ill subjects. MATERIALS AND METHODS:We studied 182 patients with systemic inflammatory response syndrome/severe sepsis or shock during the acute (day 1) and subacute phase of critical illness (day 6). All subjects had a t...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2014.06.003

    authors： Ilias I,Vassiliadi DA,Theodorakopoulou M,Boutati E,Maratou E,Mitrou P,Nikitas N,Apollonatou S,Dimitriadis G,Armaganidis A,Dimopoulou I

    更新日期：2014-12-01 00:00:00

  • Allogeneic hematopoietic stem cell transplantation after reduced intensity conditioning regimen: Outcomes of patients admitted to intensive care unit.

    abstract：PURPOSE:The prognosis of allogeneic hematopoietic stem cell transplantation (HSCT) patients admitted to the intensive care unit (ICU) is still poor. Overall, when these patients receive reduced intensity conditioning (RIC) regimens, the survival is better. To date, no study has specifically evaluated the outcome of RIC...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2015.06.020

    authors： Mokart D,Granata A,Crocchiolo R,Sannini A,Chow-Chine L,Brun JP,Bisbal M,Faucher M,Faucher C,Blache JL,Castagna L,Fürst S,Blaise D

    更新日期：2015-10-01 00:00:00

  • Quality of life assessment following amputation for septic shock: a long-term descriptive survey after symmetric peripheral gangrene.

    abstract：PURPOSE:To assess health-related quality of life (HRQOL) following rehabilitation of amputees suffering symmetric peripheral gangrene (SPG) after septic shock. MATERIAL AND METHODS:A retrospective cohort study was conducted in nine French specialized rehabilitation centers. Thirty-two ICU adult patients hospitalized b...

    journal_title：Journal of critical care

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jcrc.2019.06.027

    authors： Labroca P,Chiesa G,Laroyenne I,Borrini L,Klotz R,Phan Sy Q,Cristina MC,Martinez AB,Bollaert PE,Paysant J,Lemarié J

    更新日期：2019-10-01 00:00:00