Abstract:
OBJECTIVE:To estimate the association between fine particulate (PM2.5) and nitrogen dioxide (NO2) pollution and systemic autoimmune rheumatic diseases (SARDs). METHODS:Associations between ambient air pollution (PM2.5 and NO2) and SARDs were assessed using land-use regression models for Calgary, Alberta and administrative health data (1993-2007). SARD case definitions were based on ≥2 physician claims, or ≥1 rheumatology billing code; or ≥1 hospitalization code (for systemic lupus, Sjogren's Syndrome, scleroderma, polymyositis, dermatomyositis, or undifferentiated connective tissue disease). Bayesian hierarchical latent class regression models estimated the probability that each resident was a SARD case, based on these case definitions. The sum of individual level probabilities provided the estimated number of cases in each area. The latent class model included terms for age, sex, and an interaction term between age and sex. Bayesian logistic regression models were used to generate adjusted odds ratios (OR) for NO2 and PM2.5. pollutant models, adjusting for neighbourhood income, age, sex, and an interaction between age and sex. We also examined models stratified for First-Nations (FN) and non-FN subgroups. RESULTS:Residents that were female and/or aged >45 had a greater probability of being a SARD case, with the highest OR estimates for older females. Independently, the odds of being a SARDs case increased with PM2.5 levels, but the results were inconclusive for NO2. The results stratified by FN and non-FN groups were not distinctly different. CONCLUSION:In this urban Canadian sample, adjusting for demographics, exposure to PM2.5 was associated with an increased risk of SARDs. The results for NO2 were inconclusive.
journal_name
Environ Resjournal_title
Environmental researchauthors
Bernatsky S,Smargiassi A,Johnson M,Kaplan GG,Barnabe C,Svenson L,Brand A,Bertazzon S,Hudson M,Clarke AE,Fortin PR,Edworthy S,Bélisle P,Joseph Ldoi
10.1016/j.envres.2015.05.007subject
Has Abstractpub_date
2015-07-01 00:00:00pages
474-8eissn
0013-9351issn
1096-0953pii
S0013-9351(15)00153-Xjournal_volume
140pub_type
杂志文章abstract::Chlorine is a reactive gas used by humanity for over two centuries. Exposure to chlorine has occurred in a number of situations, including as a chemical warfare agent, in industrial and domestic exposures, and as a result of accidents and spills. The toxicology of chlorine is related almost entirely to effects in the ...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1006/enrs.2000.4110
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:Compared with a maximum collective lead (Pb) estimate of ∼1811 metric tons (MT) in exterior paint on 86,000 New Orleans houses, Pb additives in gasoline were estimated at ∼12,000 MT in New Orleans, yielding ∼9100 MT Pb exhausted as aerosols from vehicles; ∼4850 MT were particles>10 μm and ∼4200 MT were parti...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2011.06.010
更新日期:2011-11-01 00:00:00
abstract::The importance of secondary raw materials for phosphorus (P) fertilizer production is expected to increase in the future due to resource depletion, supply risks, and heavy metal contamination of fossil phosphate resources. Municipal wastewater is a promising source for P recovery. In Germany for instance, it contains ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.02.034
更新日期:2017-05-01 00:00:00
abstract::Patterns of mortality in 11 air-conditioned and 9 un-air-conditioned nursing homes in New York City have been investigated to determine the impacts of heat waves on nursing home occupants and the efficacy of air conditioning in reducing these impacts. During each of four heat waves in 1972 and 1973, the number of deat...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(78)90065-8
更新日期:1978-08-01 00:00:00
abstract::Spain is a country of southern Europe that is prone to drought, and it is likely that this type of hydrological extreme will become substantially more frequent and intense in the 21st century, which could lead to greater health risks if adequate adaptive measures are not taken. For the first time, we calculated the re...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109200
更新日期:2020-04-01 00:00:00
abstract::The effect of acute exposure to nitrogen dioxide (NO2) on anti-SRBC antibody response in two lines of Japanese quails, high and low responder, was investigated. Mean survival time of 11- to 13-week-old quails after exposure to 20 ppm NO2 was 12.0 hr. The high responder line lived longer than the low responder line. Ch...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(84)90146-4
更新日期:1984-12-01 00:00:00
abstract::Firefighter uniforms protect firefighters from exposure to potentially harmful chemicals including a range of semi-volatile organic compounds (SVOCs). Contaminated uniforms can become a secondary source of firefighters' exposure to these chemicals. There is inconsistency on the removal efficiency of SVOCs during the c...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110616
更新日期:2020-12-13 00:00:00
abstract:INTRODUCTION:Accumulating evidence indicates that arsenic (As), a potent environmental toxicant, may increase cardiovascular disease risk and adversely affect endothelial function at high levels of exposure. Pregnancy is a vulnerable time for both mother and child; however, studies examining the association between pre...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.03.056
更新日期:2017-07-01 00:00:00
abstract::The frequency and severity of flooding events will increase over the coming decades due to global climate change. While close attention has typically been paid to infrastructural and environmental outcomes of flood events, the potential adverse human health consequences associated with post-event consumption from priv...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2021.110707
更新日期:2021-01-08 00:00:00
abstract::Previous studies have evaluated the relationship between prenatal air pollution exposure and low birth weight, but the results are inconsistent. The purpose of this meta-analysis is to quantitatively analyze the relationship between maternal air pollutant exposure and low birth weight (LBW). PubMed and Web of Science ...
journal_title:Environmental research
pub_type: 杂志文章,meta分析
doi:10.1016/j.envres.2020.109970
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:Phthalates are non-persistent pollutants related to impaired metabolism and high cardiovascular risk. Their toxic metabolites are eliminated through urine and feces. Prevention policies are considered by the governments, although no therapeutic strategy to facilitate their elimination from the human body has ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110316
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Bisphenol A (BPA) is a component of polycarbonate plastics to which humans are regularly exposed at low levels, and an endocrine disruptor with effects on several hormonal systems. Bone is a sensitive hormone target tissue, and we have recently shown that in utero and lactational exposure to 25µg BPA/kg BW/d...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.07.020
更新日期:2017-11-01 00:00:00
abstract::Despite the behaviors of ZnO nanoparticles (ZnO NPs) in wastewater treatment processes have been widely explored, the impacts of ZnO NPs on the activated sludge's flocculation and sedimentation performances for solid-liquid separation have rarely been involved yet. In this study, ZnO NPs were observed to exert a dose-...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110256
更新日期:2021-01-01 00:00:00
abstract::The aim of this study was to evaluate the associations of environmental exposure to dioxins with diabetes among general inhabitants in Japan. A cross-sectional study was performed on 1374 participants, who were not occupationally exposed to dioxins, aged 15-73 years, living widely in 75 different residential areas of ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2008.06.002
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:There is growing evidence that persistent organic pollutants (POPs) may play an important role in increasing the risk of gestational diabetes mellitus (GDM). OBJECTIVES:The aim of this study was to examine the association between polychlorinated biphenyls (PCBs, 10 congeners) and polybrominated diphenyl eth...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.09.002
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Genetic and environmental factors have been recognized to play an important role in autism. The possibility that exposure to outdoor air pollution increases the risk of autism spectrum disorder (ASD) has been an emerging area of research. Herein, we present a systematic review, and meta-analysi...
journal_title:Environmental research
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.envres.2016.07.030
更新日期:2016-11-01 00:00:00
abstract::Industrially produced chemicals have been a major environmental concern across our entire Globe since the onset of rapid industrial development around the early 1900. Many of the substances being used are known to be endocrine disrupting chemicals (EDCs) and are also known to be long-range dispersed and to biomagnify ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.12.026
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Hexavalent chromium (Cr(6+)) has long been recognized as an inhalation carcinogen. Useful data on its carcinogenicity by ingestion have been slower to develop. The 2008 NTP chronic bioassay of sodium dichromate dihydrate in drinking water found clear evidence of carcinogenicity in rodents and allows a genera...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2010.08.002
更新日期:2010-11-01 00:00:00
abstract::Methylmercury (MeHg) is the most bioavailable and toxic form of the globally distributed pollutant Hg. Organisms of higher trophic levels living in aquatic ecosystems have potentially higher concentrations of MeHg. In this work, we analysed both MeHg and inorganic Mercury (Hg(II)) concentrations from dorsal feathers o...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109526
更新日期:2020-07-01 00:00:00
abstract::The unusual presentation of a factory worker with severe hemolytic anemia which remitted following splenectomy prompted a search for an environmental cause for red cell injury. The investigation showed the presence of an immunoglobulin in the patient's serum and on the red cells and small amounts of complement on red ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(78)90018-x
更新日期:1978-10-01 00:00:00
abstract::The major predictors of health risk from pesticide exposure are quantity and toxicity of pesticides reaching end-users, field workers, and persons (including children) with casual and indirect exposures to field and food residues, drift, and contaminated groundwater. Past work in Israel and the Palestinian National Au...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1997.3717
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Dichlorodiphenyl dichloroethylene (DDE) and polychlorinated biphenyls (PCBs) can be passed from mother to offspring through placental transfer or breastfeeding. Unknown is whether maternal levels can predict concentrations in adult offspring. OBJECTIVES:To test the association between maternal blood levels ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.03.009
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Experimental studies show developmental toxicity of boron and we recently found impaired weight and length in newborns of mothers exposed to boron through drinking water during pregnancy. OBJECTIVES:To evaluate potential impact of pre- and postnatal boron exposure on infant anthropometry. METHODS:In our mo...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.01.012
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:The number of studies on air pollution with birth defects as the primary outcome has increased dramatically over the past two decades, but the potential role of specific air pollutants in congenital limb anomalies remains unclear. OBJECTIVES:To evaluate associations between preconception and first-trimester...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109643
更新日期:2020-08-01 00:00:00
abstract::Chemical and natural factors have been demonstrated to interact and potentially change the toxicity of the individual stressors. Yet, while there exists a multitude of papers studying the temperature-dependent toxicity of single chemicals, little research exists on the impact of temperature on chemical mixtures. This ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.10.025
更新日期:2019-02-01 00:00:00
abstract::Trifluralin, 2,6-dinitro-N,N-dipropyl-4-trifluoromethylaniline, is a 2,6-dinitro herbicide widely used to control annual grasses and broadleaf weeds in agricultural settings. The association between trifluralin use and common cancer incidence was evaluated among 50,127 private and commercial pesticide applicators in t...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2008.01.010
更新日期:2008-06-01 00:00:00
abstract::High concentrations of uranium (mean=620 microg/L) were detected in water samples collected from private wells in a residential community. Based on isotopic analyses, the source of the uranium contamination appeared to be from naturally occurring geological deposits. In homes where well water concentrations of uranium...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/S0013-9351(03)00115-4
更新日期:2004-03-01 00:00:00
abstract::Concentration, composition and sources of polycyclic aromatic hydrocarbons (PAHs) in kitchen depositions from different sampling categories such as restaurants, university mess and houses were investigated, and associated human exposure risk through dietary intake, inhalation and dermal contact was determined. The PAH...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109648
更新日期:2020-08-01 00:00:00
abstract::In response to criticisms raised regarding a case-control study of canine malignant lymphoma, the results of several ancillary analyses are reported. The case-control study demonstrated a significant association between risk for canine malignant lymphoma and the opportunity for exposure to 2,4-dichlorophenoxyacetic ac...
journal_title:Environmental research
pub_type: 杂志文章,多中心研究
doi:10.1006/enrs.1995.1056
更新日期:1995-08-01 00:00:00
abstract:OBJECTIVE:Gut microorganisms contribute to the metabolism of environmental toxicants, including methylmercury (MeHg). Our main objective was to investigate whether associations between biomarkers for prenatal MeHg exposure and maternal gut microbiota differed between early and late gestation. METHODS:Maternal blood an...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.01.014
更新日期:2019-05-01 00:00:00