Abstract：
OBJECTIVES:The diagnosis and management of osteoporosis and osteoporotic fractures are challenging in rural and underdeveloped areas of China because medical resources are inaccessible; thus, a simple and accurate method is essential for the detection of vertebral fractures. We aimed to examine the relationship between historical height loss (HHL) and vertebral fractures in postmenopausal Chinese women. MATERIAL AND METHODS:A cross-sectional study of 255 postmenopausal women aged 50 years or older was conducted in September 2017. Demographic data, including self-reported tallest historical height and current height were analyzed. Vertebral fractures were assessed using X-ray radiography and HHL thresholds were examined using specificity and sensitivity testing. RESULTS:The average age of the 255 participants was 66.3 ± 9.0 years and their mean HHL was 3.5 ± 2.8 cm. The 24 women who were found to have vertebral fractures were older, had more years since menopause (YSM), and a larger HHL compared to those without vertebral fractures. Logistic regression analysis showed that age was a better predictor of vertebral fractures than HHL was, and the cutoff age for detecting vertebral fractures was 71 years, with an area under the receiver operating characteristic curve of 0.750. CONCLUSIONS:Although the women in this study with vertebral fractures had a greater height loss than those without fractures, it was apparent that age, rather than HHL, is the best way to determine who is most likely to develop vertebral fractures.
journal_name
Endocr Resjournal_title
Endocrine researchauthors
Chen R,Liu S,Huang M,Ou Y,Liu W,Cui R,Yuan L,Xie Z,Sheng Z,Liu Hdoi
10.1080/07435800.2020.1827263subject
Has Abstractpub_date
2021-02-01 00:00:00pages
14-19issue
1eissn
0743-5800issn
1532-4206journal_volume
46pub_type
杂志文章abstract：:The stimulation of the zona glomerulosa phenotype by a low sodium diet is characterised by increased expression of aldosterone synthase accompanied by increases in (pro)renin, bFGF, c-fos and c-jun gene transcription. In contrast ACTH diminishes the specific glomerulosa phenotype. The EGF related transmembrane protein...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435809809032720
更新日期：1998-08-01 00:00:00
abstract：:Plasminogen activator inhibitor-1 (PAI-1) levels were found to be associated with obesity, indicating that adipocytes might influence PAI-1 plasma levels. In addition, the 4G/5G promoter polymorphism of the PAI-1 gene possibly modulates PAI-1 gene transcription and, as a consequence, PAI-1 plasma levels. Metabolic par...
journal_title：Endocrine research
pub_type： 临床试验,杂志文章
doi：10.1081/erc-200035728
更新日期：2004-08-01 00:00:00
abstract：:Pretreatment of confluent human fibroblast cultures for two days in dexamethasone, serum free medium increased 10-20 fold the sensitivity of the cells to insulin-like growth factor I (IGF I) stimulation of amino acid uptake using the amino acid analog alpha-aminoisobutyric acid (AIB). This increased sensitivity result...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435808909042743
更新日期：1989-01-01 00:00:00
abstract：:Biochemical mechanisms by which analogs of thyrotropin-releasing hormone (TRH) produce their potent neuropharmacological actions on the brain remain ill-defined. We tested effects of YM14673, a novel analog of TRH, on TRH receptors in rat brains in vitro. No significant binding of [3H]YM14673 to brain plasma membranes...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435809509030493
更新日期：1995-11-01 00:00:00
abstract：:There are striking similarities between Cushing's syndrome and the 'metabolic syndrome X' since both are characterised by hypertension, insulin resistance, glucose intolerance, hyperlipidaemia, and central obesity. The possibility that cortisol contributes to the associations between multiple risk factors for cardiova...
journal_title：Endocrine research
pub_type： 杂志文章,评审
doi：10.1080/07435809609043765
更新日期：1996-11-01 00:00:00
abstract：:An analysis of the glucocorticoid receptor population of skeletal muscle and liver from dystrophic and control mice was performed. These data demonstrate that the cytosol of muscles from dystrophic animals contain a significantly higher concentration of glucocorticoid receptors (approximately 100%) relative to the cyt...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435808409046761
更新日期：1984-01-01 00:00:00
abstract：UNLABELLED:It remains difficult to pre-operatively differentiate follicular carcinoma and adenoma even under intraoperative investigations including histopathologic diagnosis of frozen sections. METHODS:We retrospectively compared dual phase thallium (Tl-201) thyroid scan and fine-needle aspiration (FNA) cytology to d...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1081/erc-120025036
更新日期：2003-08-01 00:00:00
abstract：:Islets derived from patients with persistent hyperinsulinemic hypoglycemia of infancy, PHHI, show a significant capacity to proliferate in vitro without the addition of growth factors. However, as with other differentiated cells, PHHI-derived islet cells show a loss of differentiated function with repeated subculture....
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435800500229235
更新日期：2005-01-01 00:00:00
abstract：:The present work was to study if the alpha-melanocyte-stimulating hormone (alpha-MSH) was involved in activation of the pituitary-adrenal axis (PAA) in rats. The hormone increased plasma corticosterone (CORT) level, and induced an anxiogenic response as indicated by results from the elevated plus-maze test. Intracereb...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435800009066172
更新日期：2000-08-01 00:00:00
abstract：:The purpose of this study was to examine the effects of exercise on anterior pituitary hormones (adrenocorticotropic hormone (ACTH), leutinizing hormone (LH) and growth hormone) as well as on cortisol at low altitude (350 meters below the sea level) and to compare these effects with those at a moderate level altitude ...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435809609030513
更新日期：1996-08-01 00:00:00
abstract：:The enzyme 3beta-hydroxysteroid dehydrogenase plays a crucial role in the steroidogenic process in the adrenal gland. In the present study we tried to characterize its localization and developmental changes in the rat adrenal cortex during the postnatal period, using immunohistochemical methods. The development of the...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435809909066126
更新日期：1999-02-01 00:00:00
abstract：UNLABELLED:Absract Purpose: Mutations in the TPO gene have been reported to cause congenital hypothyroidism (CH), and our aim in this study was to determine the genetic basis of congenital hypothyroidism in two affected children coming from a consanguineous family. METHODS:Since CH is usually inherited in autosomal re...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435800.2014.967354
更新日期：2015-01-01 00:00:00
abstract：:Purpose: Transthyretin (TTR) is a protein with a growing number of biological functions in addition to its well-established binding and circulatory transport of thyroxine, and indirect retinoid transport through interaction with retinol-binding protein. Misfolded and aggregated wild-type and mutant TTRs are involved i...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435800.2019.1694538
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:Some similar factors, such as genetic susceptibility and subinflammation/autoimmunity, contribute to development of both polycystic ovary syndrome (PCOS) and Hashimoto's thyroiditis (HT), suggesting a potential pathogenic link between the two common disorders. In this study, we investigated the relationship b...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435800.2015.1015730
更新日期：2015-01-01 00:00:00
abstract：:Hashimoto's thyroiditis (HT) is one of the most common organ-specific autoimmune diseases. Increasing evidence indicates that HT may be characterized by an imbalance in the helper T cell subsets Th1 and Th2. Traditional Chinese Medicine (TCM) considers HT as a chronic exhaustion disease, leading to deficiency of qi. I...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435800.2015.1066800
更新日期：2016-01-01 00:00:00
abstract：:Several lines of evidence have suggested that the nuclear receptor Steroidogenic Factor-1 (SF-1 or Ad4BP) may be directly involved in the cAMP-dependent regulation of steroid hydroxylase genes in adrenocortical cells. In the bovine CYP17 gene, which encodes the cytochrome P450 17alpha-hydroxylase, an SF-1 site is pres...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435809809032638
更新日期：1998-08-01 00:00:00
abstract：:In order to clarify the roles of cholinergic and serotonergic neurotransmission in the mediation of exercise-induced growth hormone (GH) release, normal young volunteers of both sexes were studied. Exercise was for 20 minutes at 800 kpm for the men and 500 kpm for the women. Pretreatment with 0.4 mg atropine 1 hour pr...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435808609035433
更新日期：1986-01-01 00:00:00
abstract：:Purpose: Limited and contradictory data on the circulating levels of glucagon-like peptide (GLP-1) and resistin in hepatitis C virus genotype-4 (HCV-4) cirrhotic patients are present. Thus, this study aimed to evaluate their concentrations and to investigate the association between total GLP-1, resistin, and insulin r...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435800.2019.1627551
更新日期：2020-02-01 00:00:00
abstract：:Leptin, the product of the ob gene, is an adipose-tissue secreted hormone, which regulates satiety, metabolic rate and thermogenesis. Many lines of evidence suggest the existence of mutual relationships between leptin and adrenal-cortex secretion, but in vivo studies gave rather conflicting results. Therefore, we have...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435809809135531
更新日期：1998-05-01 00:00:00
abstract：:The prostate gland of humans and other animals has the unique function of accumulating and secreting extraordinarily high levels of citrate. The prostate secretory epithelial cells synthesize citrate which, due to a limiting mitochondrial (m-) aconitase, accumulates rather than being oxidized. Thus citrate is essentia...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435800009040143
更新日期：2000-02-01 00:00:00
abstract：:The adrenal cortex is a dynamic organ in which the cells of the outer cortex continually divide. It is well known that this cellular proliferation is dependent on constant stimulation from peptides derived from the ACTH precursor proopiomelanocortin (POMC) since disruption of pituitary corticotroph function results in...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1081/erc-120016801
更新日期：2002-11-01 00:00:00
abstract：:Addition of cAMP (as the dibutyryl compound) to a primary culture of mouse Leydig cells caused the accumulation of a protein, i(b), with the same dependence on cAMP concentration as the increase in testosterone synthesis. Stimulation of both protein i(b) and testosterone production were inhibited by cycloheximide. Add...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435808609035449
更新日期：1986-01-01 00:00:00
abstract：:11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) catalyzes the interconversion of cortisol (F) to inactive cortisone (E) in man (corticosterone (B) to 11-dehydrocorticosterone (A) in rodents) and plays a crucial role in regulating corticosteroid hormone action. Two isoforms of this enzyme have been characterized; a ...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435809609043775
更新日期：1996-11-01 00:00:00
abstract：:Immunohistochemistry using a StAR peptide antiserum had previously revealed strong staining in rat and bovine adrenal medulla, suggesting the presence of a protein immunogenically related to StAR. Western blots of bovine medulla tissue homogenates showed the principal adrenal medullary immuno-reactive species to have ...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.3109/07435800009048594
更新日期：2000-11-01 00:00:00
abstract：:The sexual dimorphism of life span and caloric restriction effects in numerous species suggest that estradiol (E2) is protective against oxidative damage. The only direct test of E2's protective effect in mice against in vivo oxidative stress to date may have been confounded by E2's direct chemical action as an antiox...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435800902913600
更新日期：2009-01-01 00:00:00
abstract：:Diabetes mellitus impairs ventricular function, which itself may be disparately influenced by gender. This study compared the impact of gender on cardiac contractile response in ventricular myocytes from wild-type FVB and calmodulin-induced diabetic transgenic (OVE26) mice at young (2 month) and older (11 month) age. ...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1081/erc-120022318
更新日期：2003-05-01 00:00:00
abstract：:It is now well documented that obesity is associated with a chronic low-grade inflammatory state. Levels of high-sensitivity C-reactive protein, a marker of systemic inflammation and a mediator of atherothrombotic disease, have been shown to correlate with cardiovascular disease risk. Our objective was to evaluate the...
journal_title：Endocrine research
pub_type： 临床试验,杂志文章
doi：10.1081/erc-200033541
更新日期：2004-08-01 00:00:00
abstract：INTRODUCTION:Adenosine deaminase (ADA), purine nucleoside phosphorylase (PNPase), S-adenosylhomocysteine hydrolase (SAHH), 5'-nucleotidase (5N), and deoxycytidine kinase (dCK) are involved in purine salvage metabolism. Changes of the activities of the above enzymes have been observed in blood cells in patients with imm...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1081/erc-120015059
更新日期：2002-08-01 00:00:00
abstract：:Comparison of binding of 125I-porcine FSH to porcine granulosa cells from small and large ovarian follicles indicated that binding is dependent on both time and temperature. At 37 C, binding of ligand is more than four times higher in cells from small follicles than in cells from large follicles within 30 minutes of t...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1080/07435809409035857
更新日期：1994-02-01 00:00:00
abstract：:There is controversy concerning the effects of progestins on bone. Norethindrone acetate (NETA) is synthetic progesterone that also has estrogenic and androgenic effects. We tested its effects on hormone levels, lipids and biochemical markers of bone turnover in postmenopausal women who were on estrogen replacement th...
journal_title：Endocrine research
pub_type： 杂志文章
doi：10.1081/erc-100107870
更新日期：2001-11-01 00:00:00
