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Comparison of Proximal Junctional Failure and Functional Outcomes Across Varying Definitions of Proximal Junctional Kyphosis.

Abstract：

BACKGROUND:Proximal junctional kyphosis (PJK) is a well-recognized complication following surgery for adult spinal deformity (ASD); however, definitions for PJK and its clinical implications can significantly vary by study. This study compares multiple definitions of PJK and describes incidence and clinical significance by definition. METHODS:From 2014 to 2019, patients with ASD who underwent spinal fusion were identified. Nine definitions of PJK were created based on previously established definitions using the following upper instrumented vertebra +2 (UIV+2) sagittal Cobb measurements: A= ≥10 postoperative AND preoperative, B = ≥10 postoperative, C = ≥10 preoperative, D = ≥15 postoperative AND preoperative, E = ≥15 postoperative, F = ≥15 preoperative, G = ≥20 postoperative AND preoperative, H = ≥20 postoperative, I = >20 preoperative. Incidence of PJK was calculated by definition. Area under the curve (AUC) was calculated based on a receiver operating characteristic to assess ability to predict proximal junctional failure (PJF). Univariate analysis was performed to assess association with postoperative Oswestry Disability Index (ODI) scores. RESULTS:Across 82 patients, the incidence of PJK and AUC by definition was as follows: A = 47%, 0.47; B = 72%, 0.65; C = 49%, 0.45; D = 27%, 0.46; E = 57%, 0.62; F = 27%, 0.46; G = 10%, 0.55; H = 40%, 0.71; I = 10%, 0.55. No definition was associated with postoperative ODI scores (P < 0.05). CONCLUSIONS:The incidence of PJK significantly decreased with stricter definitions. Definitions utilizing only postoperative UIV+2 values had higher incidences but were more likely to capture patients who developed PJF. No definition was associated with postoperative ODI scores. UIV+2 ≥20 was best in distinguishing patients who developed PJF.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Ton A,Alluri RK,Kang HP,Kim A,Hah RJ

doi

10.1016/j.wneu.2020.10.034

subject

Has Abstract

pub_date

2020-10-20 00:00:00

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(20)32226-9

pub_type

杂志文章

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Comparison of Proximal Junctional Failure and Functional Outcomes Across Varying Definitions of Proximal Junctional Kyphosis.